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Chicken Intestinal L Cells and Glucagon-like Peptide-1 Secretion [PDF]

open access: yesThe Journal of Poultry Science, 2020
Many types of endocrine cells have been identified in the gastroenteropancreatic system of vertebrates, which have subsequently been named with alphabet (s).
Kohzy Hiramatsu
doaj   +2 more sources

Labeling and Characterization of Human GLP-1-Secreting L-cells in Primary Ileal Organoid Culture

open access: yesCell Reports, 2020
Summary: Glucagon-like peptide-1 (GLP-1) from intestinal L-cells stimulates insulin secretion and reduces appetite after food ingestion, and it is the basis for drugs against type-2 diabetes and obesity. Drugs targeting L- and other enteroendocrine cells
Deborah A. Goldspink   +8 more
doaj   +2 more sources

Addressing Teacher Retention within the First Three to Five Years of Employment [PDF]

open access: yesAthens Journal of Education, 2023
Teachers’ perceptions of long-term career success are largely related to the levels of support they receive early on in their careers. This study on teacher retention and the factors that influence teacher choice to remain in the field after the first ...
Paticia Cells   +4 more
doaj   +1 more source

Alloreactivity of Allogeneic Mesenchymal Stem/Stromal Cells and Other Cellular Therapies: A Concise Review

open access: yesStem Cells International, 2022
Cellular therapies, deemed live medicine, have brought a wave of new generation biological therapies to treat previously untreatable diseases such as cancers and degenerative diseases like osteoarthritis.
Kiran Shah   +6 more
doaj   +1 more source

INTERACTION OF AN INTERFERON WITH L CELLS [PDF]

open access: yesJournal of Bacteriology, 1963
Lockart, Royce Z., Jr . (The University of Texas, Austin) and Barbara Horn . Interaction of an interferon with L cells. J. Bacteriol. 85: 996–1002. 1963.—Data were presented on the effect of time of exposure and concentration of an interferon in provoking viral inhibition in L ...
R Z, LOCKART, B, HORN
openaire   +2 more sources

Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1

open access: yesNature Communications, 2021
Haematopoietic stem cells (HSCs) are characterized by their self-renewal potential and associated dormancy. Here the authors show that niche produced netrin-1 preserves HSC quiescence and self-renewal via neogenin-1, and that decline of netrin-1 ...
Simon Renders   +31 more
doaj   +1 more source

Administration of L-citrulline prevents Plasmodium growth by inhibiting/ modulating T-regulatory cells during malaria pathogenesis

open access: yesJournal of Vector Borne Diseases, 2022
Background & objectives: Malaria affects around 228 million people all over the globe. Malaria causing parasite Plasmodium infection leads to activation of immune responses. The growth of parasite and immune activation requires semi essential amino acids
Vikky Awasthi, Rubika Chauhan, Jyoti Das
doaj   +1 more source

Microbial regulation of the L cell transcriptome [PDF]

open access: yesScientific Reports, 2018
AbstractL cells are an important class of enteroendocrine cells secreting hormones such as glucagon like peptide-1 and peptide YY that have several metabolic and physiological effects. The gut is home to trillions of bacteria affecting host physiology, but there has been limited understanding about how the microbiota affects gene expression in L cells.
Arora, Tulika   +8 more
openaire   +3 more sources

THE SOURCE OF LIPID ACCUMULATION IN L CELLS [PDF]

open access: yesThe Journal of Cell Biology, 1961
Strain L cells accumulate lipid, concurrent with cessation of protein synthesis, in the stationary phase of growth from the extracellular medium and as a result of de novo synthesis. Cells which have been more severely damaged with an amino acid analogue also accumulate lipid from the extracellular medium, but synthesize very little lipid from labeled ...
K G, Bensch, D W, King, E L, Socolow
openaire   +2 more sources

L-Canavanine potentiates the cytotoxicity of doxorubicin and cisplatin in arginine deprived human cancer cells [PDF]

open access: yesPeerJ, 2016
The non-protein amino acid L-canavanine (L-CAV), an antimetabolite of L-arginine (L-ARG), can alter the 3D conformation of proteins when incorporated into a protein instead of L-ARG. L-CAV inhibits the proliferation of some tumour cells.
Agustina DR Nurcahyanti, Michael Wink
doaj   +2 more sources

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