Results 91 to 100 of about 1,561,247 (279)

A simple and optimal ancestry labeling scheme for trees

open access: yes, 2015
We present a $\lg n + 2 \lg \lg n+3$ ancestry labeling scheme for trees. The problem was first presented by Kannan et al. [STOC 88'] along with a simple $2 \lg n$ solution. Motivated by applications to XML files, the label size was improved incrementally
A Deutsch   +6 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Trajectory-Based Dynamic Map Labeling

open access: yes, 2013
In this paper we introduce trajectory-based labeling, a new variant of dynamic map labeling, where a movement trajectory for the map viewport is given. We define a general labeling model and study the active range maximization problem in this model.
A. Gemsa   +9 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

A Study on Integer Additive Set-Graceful Graphs [PDF]

open access: yes, 2015
A set-labeling of a graph $G$ is an injective function $f:V(G)\to \mathcal{P}(X)$, where $X$ is a finite set and a set-indexer of $G$ is a set-labeling such that the induced function $f^{\oplus}:E(G)\rightarrow \mathcal{P}(X)-\{\emptyset\}$ defined by $f^
Germina, K. A., Sudev, N. K.
core  

Weak Set-Labeling Number of Certain IASL-Graphs

open access: yes, 2015
Let $\mathbb{N}_0$ be the set of all non-negative integers, let $X\subset \mathbb{N}_0$ and $\mathcal{P}(X)$ be the the power set of $X$. An integer additive set-labeling (IASL) of a graph $G$ is an injective function $f:V(G)\to \mathcal{P}(\mathbb{N}_0)$
Chithra, K. P.   +2 more
core   +1 more source

Molecular architecture of human polycomb repressive complex 2

open access: yeseLife, 2012
Polycomb Repressive Complex 2 (PRC2) is essential for gene silencing, establishing transcriptional repression of specific genes by tri-methylating Lysine 27 of histone H3, a process mediated by cofactors such as AEBP2.
Claudio Ciferri   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Topological Integer Additive Set-Sequential Graphs

open access: yes, 2015
Let $\mathbb{N}_0$ denote the set of all non-negative integers and $X$ be any non-empty subset of $\mathbb{N}_0$. Denote the power set of $X$ by $\mathcal{P}(X)$. An integer additive set-labeling (IASL) of a graph $G$ is an injective set-valued function $
Augustine, Germina   +2 more
core   +2 more sources

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