Results 21 to 30 of about 37,366 (242)

Regulatory region of the divergent Klebsiella pneumoniae lac operon [PDF]

open access: bronzeJournal of Bacteriology, 1985
The chromosomal DNA that lies between the lacI and lacZ genes of Klebsiella pneumoniae constitutes a 196-base pair intercistronic region that contains regulatory sequences for both genes. The probable locations of specific regulatory elements for both lacI and lacZ genes were determined by analogy with the corresponding Escherichia coli sequences.
W E Buvinger, Margaret A. Riley
openalex   +3 more sources

The lac operon in the wild

open access: green, 2017
The lac operon is a classic model system for bacterial gene regulation, and has been studied extensively in E. coli, a classic model organism. However, not much is known about E. coli’s ecology and life outside the laboratory, in particular in soil and water environments.
Fabienne Jesse
openalex   +2 more sources

Genomic characterization of Klebsiella spp. from bovine mastitis: dissemination of a conserved, highly transmissible lacacq+ fec+ plasmid drives burden of disease [PDF]

open access: yesApplied and Environmental Microbiology
Bovine mastitis poses a significant health concern for dairy cattle and a major economic burden on the dairy industry. Klebsiella spp. are important mastitis pathogens, with previous studies identifying lactose-utilization (lacacq) and iron-acquisition ...
Michael Biggel   +5 more
doaj   +2 more sources

Modeling network dynamics: the lac operon, a case study [PDF]

open access: greenThe Journal of cell biology, 2004
We use the lac operon in Escherichia coli as a prototype system to illustrate the current state, applicability, and limitations of modeling the dynamics of cellular networks. We integrate three different levels of description -molecular, cellular, and that of cell population- into a single model, which seems to capture many experimental aspects of the ...
José M. G. Vilar   +2 more
openalex   +4 more sources

Identification of an intestine-specific promoter and inducible expression of bacterial α-galactosidase in mammalian cells by a lac operon system [PDF]

open access: yesJournal of Animal Science and Biotechnology, 2012
Background α-galactosidase has been widely used in animal husbandry to reduce anti-nutritional factors (such as α-galactoside) in feed. Intestine-specific and substrate inducible expression of α-galactosidase would be highly beneficial for transgenic ...
Ya-Feng Zhai   +8 more
doaj   +2 more sources

Divergent Evolution and Local Establishment of Multidrug-Resistant <i>Shigella sonnei</i> in China. [PDF]

open access: yesMedComm (2020)
• Evolutionary history and local establishment of Chinese Shigella sonnei are unclear. • Chinese S. sonnei developed into four clades and ONPG‐negative variants. • The antimicrobial resistance phenotype of Clade I was due to an IncB/O/K/Z plasmid. • Antimicrobial resistance of Clade II was due to IncFII and IncB/O/K/Z plasmids.
Liu K   +26 more
europepmc   +2 more sources

The secondary messenger ppGpp interferes with cAMP-CRP regulon by promoting CRP acetylation in Escherichia coli.

open access: yesPLoS ONE, 2021
The cAMP-CRP regulon coordinates transcription regulation of several energy-related genes, the lac operon among them. Lactose, or IPTG, induces the lac operon expression by binding to the LacI repressor, and releasing it from the promoter sequence.
Chunghwan Ro   +2 more
doaj   +2 more sources

The plasmid-encoded lactose operon plays a vital role in the acid production rate of Lacticaseibacillus casei during milk beverage fermentation

open access: yesFrontiers in Microbiology, 2022
Lacticaseibacillus casei is used extensively in the fermented milk-beverage industry as a starter culture. Acid production capacity during fermentation is the main criterion for evaluating starters although it is strain-dependent. In this study, the acid
Xiaoxia Li   +11 more
doaj   +1 more source

Finite state machine and Markovian equivalents of the lac Operon in E. coli bacterium

open access: yesAIMS Bioengineering, 2022
The lac operon in E. coli has been extensively studied by computational biologists. The bacterium uses it to survive in the absence of glucose, utilizing lactose for growth.
Urooj Ainuddin, Maria Waqas
doaj   +1 more source

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