Catabolite repression of the lac operon. Effect of mutations in the lac promoter [PDF]
Biochemical Journal, 1970 1. Several lac diploid strains of Escherichia coli were constructed and tested to discover whether mutations in the lac promoter alleviate catabolite repression. 2. In each of these diploids the chromosome carries one of the promoter mutations, L8, L29 or L1; so that the rate of synthesis of the enzymes of the lac operon is only 2–6% of the fully ...
Michael D. Yudkin
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Determinants of bistability in induction of the Escherichia coli lac operon [PDF]
IET Systems Biology, 2008 19 pages, 10 figures, First q-bio Conference on Cellular Information ...
David W. Dreisigmeyer +4 more
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, 2017 The lac operon is a classic model system for bacterial gene regulation, and has been studied extensively in E. coli, a classic model organism. However, not much is known about E.
Jesse, Fabienne
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A galactose-based auto-expression system improves T7-inducible protein production in Escherichia coli [PDF]
Scientific ReportsProtein production using Escherichia coli is a cornerstone of modern biotechnology. In this study, we developed a novel auto-expression medium to maximize protein production. Each E.
James Bosco +23 more
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Bistable Behavior in a Model of the lac Operon in Escherichia coli with Variable Growth Rate [PDF]
Biophysical Journal, 2007 This work is a continuation from another study previously published in this journal. Both the former and the present works are dedicated to investigating the bistable behavior of the lac operon in Escherichia coli from a mathematical modeling point of ...
Moisés Santillán
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Corrigendum: The selective advantage of the lac operon for Escherichia coli is conditional on diet and microbiota composition [PDF]
Frontiers in Microbiology, 2023 Catarina Pinto +3 more
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Protein distributions from a stochastic model of the lac operon of E. coli with DNA looping: analytical solution and comparison with experiments. [PDF]
PLoS One, 2014 Choudhary K, Oehler S, Narang A.
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cAMP does not have an important role in carbon catabolite repression of the Escherichia coli lac operon [PDF]
Nature Reviews Microbiology, 2009 Atul Narang
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PLoS ONE, 2021 The cAMP-CRP regulon coordinates transcription regulation of several energy-related genes, the lac operon among them. Lactose, or IPTG, induces the lac operon expression by binding to the LacI repressor, and releasing it from the promoter sequence.
Chunghwan Ro +2 more
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Frontiers in Microbiology, 2022 Lacticaseibacillus casei is used extensively in the fermented milk-beverage industry as a starter culture. Acid production capacity during fermentation is the main criterion for evaluating starters although it is strain-dependent. In this study, the acid
Xiaoxia Li +11 more
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