Results 41 to 50 of about 37,366 (242)
MicrobiologyOpen, 2019 Bacteria can utilize diverse sugars as carbon and energy source, but the regulatory mechanisms directing the choice of the preferred substrate are often poorly understood.
Tamara Aleksandrzak‐Piekarczyk +2 more
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Development of a Positive-readout Mouse Model of siRNA Pharmacodynamics
Molecular Therapy: Nucleic Acids, 2013 Development of RNAi-based therapeutics has the potential to revolutionize treatment options for a range of human diseases. However, as with gene therapy, a major barrier to progress is the lack of methods to achieve and measure efficient delivery for ...
Mark Stevenson +9 more
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A modified consumer inkjet for spatiotemporal control of gene expression.
PLoS ONE, 2009 This paper presents a low-cost inkjet dosing system capable of continuous, two-dimensional spatiotemporal regulation of gene expression via delivery of diffusible regulators to a custom-mounted gel culture of E. coli. A consumer-grade, inkjet printer was
Daniel J Cohen +2 more
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Biomedical and Biotechnology Research Journal, 2022 Background: The repeating elements in the genes or genomes of living organisms are associated with a variety of functions at the molecular level. Mirror repeats (MRs) are unique type of repeat sequences among them, which are found to be linked with H-DNA
Sandeep Yadav +2 more
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A Type System for a Stochastic CLS [PDF]
, 2009 The Stochastic Calculus of Looping Sequences is suitable to describe the evolution of microbiological systems, taking into account the speed of the described activities.
Angelo Troina +3 more
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Quantitative Characterization of Combinatorial Transcriptional Control of the Lactose Operon of E. coli [PDF]
, 2007 It is the goal of systems biology to understand the behavior of the whole in terms of the knowledge of the parts. This is hard to achieve in many cases due to the difficulty of characterizing the many constituents and their complex web of interactions ...
Hwa, T. +3 more
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The Role of the [2Fe-2S] Cluster of Escherichia coli IscR in Responding to Redox-Cycling Agents. [PDF]
Mol MicrobiolRedox cycling agents like phenazine methosulfate (PMS) are known for upsetting cellular redox balance. Here we describe how PMS leads to upregulation of the ISC and SUF Fe‐S cluster biogenesis pathways in Escherichia coli when PMS oxidizes the [2Fe‐2S]1+ cluster of the transcription factor IscR, thereby derepressing the operon encoding ISC and, when a ...
Banerjee R +3 more
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Use of a Role-Playing Activity To Increase Student Understanding of Bacterial Gene Regulation
Journal of Microbiology & Biology Education, 2023 Undergraduate students often struggle to understand the basics of bacterial gene regulation, a key concept in microbiology. They find it hard to visualize the architecture of a bacterial operon or how the gene, RNA, and protein components interact with ...
Vinaya Sampath
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CadC-mediated activation of the cadBA promoter in Escherichia coli [PDF]
, 2005 The transcriptional activator CadC in Escherichia coli, a member of the ToxR-like proteins, activates transcription of the cadBA operon encoding the lysine decarboxylase CadA and the lysine-cadaverine antiporter CadB. cadBA is induced under conditions of
Jung, K., Kuper, C.
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The Role of Integration Host Factor in Escherichia coli Persister Formation
mBio, 2022 Persisters represent a small subpopulation of cells that are tolerant of killing by antibiotics and are implicated in the recalcitrance of chronic infections to antibiotic therapy.
Samantha E. Nicolau, Kim Lewis
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