ATP-Sensitive Potassium Channel-Mediated Lactate Effect on Orexin Neurons: Implications for Brain Energetics during Arousal [PDF]
, 2010 Active neurons have a high demand for energy substrate, which is thought to be mainly supplied as lactate by astrocytes. Heavy lactate dependence of neuronal activity suggests that there may be a mechanism that detects and controls lactate levels and/or ...
Hirasawa, Michiru, Parsons, Matthew P.
core +1 more source
Quantile regression for longitudinal functional data with application to feed intake of lactating sows [PDF]
, 2023 This article focuses on the study of lactating sows, where the main interest is the influence of temperature, measured throughout the day, on the lower quantiles of the daily feed intake. We outline a model framework and estimation methodology for quantile regression in scenarios with longitudinal data and functional covariates. The quantile regression
arxiv +1 more source
Is Lactate an Oncometabolite? Evidence Supporting a Role for Lactate in the Regulation of Transcriptional Activity of Cancer-Related Genes in MCF7 Breast Cancer Cells. [PDF]
, 2019 Lactate is a ubiquitous molecule in cancer. In this exploratory study, our aim was to test the hypothesis that lactate could function as an oncometabolite by evaluating whether lactate exposure modifies the expression of oncogenes, or genes encoding ...
Brooks, George A +4 more
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A Metabolite Specific 3D Stack-of-Spiral bSSFP Sequence for Improved Lactate Imaging in Hyperpolarized [1-$^{13}$C]Pyruvate Studies on a 3T Clinical Scanner [PDF]
Magn Reson Med. 2020; 84: 1113-1125, 2020 Purpose: The balanced steady-state free precession sequence has been previously explored to improve the efficient use of non-recoverable hyperpolarized $^{13}$C magnetization, but suffers from poor spectral selectivity and long acquisition time. The purpose of this study was to develop a novel metabolite-specific 3D bSSFP ("MS-3DSSFP") sequence with ...
arxiv +1 more source
Molecules, 2014 Angelica sinensis (AS) is a well-known medicinal herb and food material with antioxidative and multifunctional pharmacological activities. However, we lack evidence of the effect of AS on exercise performance and physical fatigue.
Tzu-Shao Yeh +3 more
doaj +1 more source
Endogenous Nutritive Support after Traumatic Brain Injury: Peripheral Lactate Production for Glucose Supply via Gluconeogenesis. [PDF]
, 2015 We evaluated the hypothesis that nutritive needs of injured brains are supported by large and coordinated increases in lactate shuttling throughout the body.
Brooks, George A +7 more
core +1 more source
On the Handwriting Tasks' Analysis to Detect Fatigue [PDF]
Applied Sciences 10, no. 21: 7630 (2020), 2022 Practical determination of physical recovery after intense exercise is a challenging topic that must include mechanical aspects as well as cognitive ones because most of physical sport activities, as well as professional activities (including brain computer interface-operated systems), require good shape in both of them.
arxiv +1 more source
Adipocyte, 2019 White adipose tissue (WAT) nucleated stromal cells (NSC) play important roles in regulation, defense, regeneration and metabolic control. In WAT sites, the proportions and functions of NSC change under diverse physiological or pathologic conditions.
Floriana Rotondo +5 more
doaj +1 more source
Comment on "A compilation and bioenergetic evaluation of syntrophic microbial growth yields in anaerobic digestion" by Patón, M. and Rodríguez, J. [Water Research 162 (2019), 516-517] [PDF]
Water Research 173 (2020) 115347, 2021 Recent efforts have focused on providing a systematic analysis of syntrophic microbial growth yields. These biokinetic parameters are key to developing an accurate mathematical description of the anaerobic digestion process. The agreement between experimentally determined growth yields and those obtained from bioenergetic estimations is therefore of ...
arxiv +1 more source
Indian Journal of Anaesthesia, 2015 Background and Aims: Advanced monitoring targeting haemodynamic and oxygenation variables can improve outcomes of surgery in high-risk patients. We aimed to assess the impact of goal directed therapy (GDT) targeting cardiac index (CI) and oxygen ...
Lakshmi Kumar +2 more
doaj +1 more source