Results 1 to 10 of about 288,915 (310)
Risk of lactic acidosis in type 2 diabetes patients using metformin: A case control study. [PDF]
PLoS ONE, 2018 Metformin constitutes first-line treatment of type 2 diabetes mellitus. It is presumed to have lactic acidosis as a dangerous, but rare, side effect.To estimate the incidence rate of lactic acidosis in patients with type 2 diabetes mellitus as well as to
Abdellatif Aharaz +5 more
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Metformin-Associated Lactic Acidosis [PDF]
Endocrinology and Metabolism, 2015 Introduction Metformin is a first line oral medication for diabetes mellitus shown to decrease cardiovascular morbidity and mortality. Though the prevalence of metformin-associated lactic acidosis (MALA) is low, mortality is high, ranging from 25-50 ...
Sunghwan Suh
doaj +4 more sources
Reversible Severe Acute Lactic Acidosis Caused by Thiamine Deficiency in Intensive Care Unit [PDF]
Case Reports in Critical CareLactic acidosis is a common cause of metabolic acidosis in hospitalized patients. It is typically caused by hypoperfusion and anaerobic metabolism and is often associated with sepsis.
Jisu Hong +4 more
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Afebrile Recurrent Cellulitis Complicated by Linezolid-Induced Lactic Acidosis in an Elderly Patient. [PDF]
Am J Case RepYambó-Chévere Y, Bermúdez-Rivera R.
europepmc +3 more sources
Dancing with death at pH 6.8 and lactate of 29 mmol/L: extreme survival in severe metformin-associated lactic acidosis - a case report. [PDF]
Front Med (Lausanne)Kortli S, Amathieu R, Ghalayini M.
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Saudi Pharmaceutical Journal, 2022 Linezolid is an oxazolidinone antibiotic. Linezolid-associated lactic acidosis has been reported in 6.8% of linezolid-treated patients. Lactic acidosis is associated with poor clinical outcomes, with high blood lactate levels resulting in organ ...
Naiju Zhang +5 more
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The genomic analysis of lactic acidosis and acidosis response in human cancers. [PDF]
PLoS Genetics, 2008 The tumor microenvironment has a significant impact on tumor development. Two important determinants in this environment are hypoxia and lactic acidosis.
Julia Ling-Yu Chen +8 more
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Kidney International, 1986 Lactic acidosis is a metabolic disturbance characterized by an increase of the production/clearance ratio of lactate. Lactate is a catabolite of glycolysis when this takes place under anaerobic conditions. Clinically LA is characterized by: signs of acidosis, venous blood lactate greater than 5 mMol/l, arterial pH less than 7.25.
MOLINATTI GM +3 more
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Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA. [PDF]
PLoS Genetics, 2010 Although lactic acidosis is a prominent feature of solid tumors, we still have limited understanding of the mechanisms by which lactic acidosis influences metabolic phenotypes of cancer cells. We compared global transcriptional responses of breast cancer
Julia Ling-Yu Chen +9 more
doaj +1 more source
Type B Lactic Acidosis in A Child with Relapsed non-Hodgkin Lymphoma
Journal of Pediatric Emergency and Intensive Care Medicine, 2023 Lactic acidosis is a major cause of metabolic acidosis in critically ill patients. Herein we report a child with relapsed non-Hodgkin’s lymphoma admitted to the pediatric intensive care unit (PICU) with profound lactic acidosis.
Tolga Besci +5 more
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