Results 91 to 100 of about 6,201 (226)

Relationship of paraoxonase-1 and paraoxonase-3 with routine laboratory tests and oxidative stress in type 2 diabetes mellitus

Türk Biyokimya Dergisi
We aimed to investigate the relationship between serum paraoxonase-1 (PON1) and paraoxonase-3 (PON3) levels and activities with hemoglobin A1c (HbA1c), serum fasting blood glucose, lipid profile, and oxidative stress in patients with type 2 diabetes ...
Ucar Yagcı Yagmur, Yılmaz Bulbul Buket, Sut Necdet, Ozgun Eray   +3 more
doaj   +1 more source

Human paraoxonase 2 [PDF]

Human paraoxonase 2 (PON2), which is a member of the paraoxonase family, possesses unique properties that distinguish it from PON1 and PON3. PON2 is ubiquitously expressed in many different tissue types and is highly expressed in the vital organs, such
Permpongpaiboon, Thinnakorn, Porntadavity, Sureerut, Sukketsiri, Wanida   +2 more
core   +1 more source

PvdQ Quorum Quenching Acylase Attenuates Pseudomonas aeruginosa Virulence in a Mouse Model of Pulmonary Infection [PDF]

, 2018
Pseudomonas aeruginosa is the predominant pathogen in pulmonary infections associated with cystic fibrosis. Quorum sensing (QS) systems regulate the production of virulence factors and play an important role in the establishment of successful P ...
Melgert, Barbro N., Quax, Wim J., Setroikromo, Rita, Utari, Putri D.   +3 more
core   +3 more sources

Degradation of Bacterial Quorum Sensing Signaling Molecules by the Microscopic Yeast Trichosporon loubieri Isolated from Tropical Wetland Waters

Sensors, 2013
Proteobacteria produce N-acylhomoserine lactones as signaling molecules, which will bind to their cognate receptor and activate quorum sensing-mediated phenotypes in a population-dependent manner.
Cheng-Siang Wong, Chong-Lek Koh, Choon-Kook Sam, Jian Woon Chen, Yee Meng Chong, Wai-Fong Yin, Kok-Gan Chan   +6 more
doaj   +1 more source

Negative association between paraoxonase 2, anthropometric markers and metabolic syndrome

Open Life Sciences, 2015
Background Metabolic syndrome (MS) has a great impact on cardiovascular mortality and morbidity. Our aim was to investigate the association of MS with some oxidant and antioxidant markers, including pro-and antioxidant status of peripheral blood ...
Mihai Andrada, Lixandru Daniela, Alexandru Petruta, Stoian Irina, Carniciu Simona, Mitu Manuela, Guja Cristian, Ionescu-Tirgoviste Constantin   +7 more
doaj   +1 more source

Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer. [PDF]

, 2018
Ovarian cancer (OC) is most lethal malignancy among all gynecological cancer. Large bodies of evidences suggest that mitochondrial-derived ROS play a critical role in the development and progression of OC.
Devarajan, Asokan, Farias-Eisner, Gina, Farias-Eisner, Robin, Fogelman, Alan M, Gao, Feng, Grijalva, Victor, Nwokedi, Josephine, Reddy, Srinivasa T, Su, Feng, Trost, Hannah, Yalamanchi, Ashna, Yalamanchi, Meghna   +11 more
core   +3 more sources

Degradation of pathogen quorum-sensing molecules by soil bacteria: a preventive and curative biological control mechanism [PDF]

, 2017
The plasmid pME6863, carrying the aiiA gene from the soil bacterium Bacillus sp. A24 that encodes a lactonase enzyme able to degrade N-acyl-homoserine lactones (AHLs), was introduced into the rhizosphere isolate Pseudomonas fluorescens P3. This strain is
Constantinescu, Florica, Duffy, Brion, Défago, Geneviève, Michel, Laurent, Molina, Lázaro, Reimmann, Cornelia   +5 more
core  

Identification of QuiP, the Product of Gene PA1032, as the Second Acyl-Homoserine Lactone Acylase of Pseudomonas aeruginosa PAO1 [PDF]

, 2006
The relevance of the acyl homoserine lactone (acyl-HSL) quorum signals N-3-oxododecanoyl-homoserine lactone (3OC12HSL) and N-butanoyl-homoserine lactone to the biology and virulence of Pseudomonas aeruginosa is well investigated.
Huang, Jean J., Leadbetter, Jared R., Petersen, Ashley, Whiteley, Marvin   +3 more
core   +1 more source

Arylesterase activity of Paraoxonase 1 - prognostic factor for one-year survival in patients with acute myocardial infarction

Romanian Journal of Laboratory Medicine, 2018
Introduction: Reduced serum levels of paraoxonase 1 (PON1) activities are associated with diseases involving increased oxidative stress, such as acute coronary syndrome.
Ciumărnean Lorena, Greavu Mihai, Vesa Ştefan C, Tanțău Alina I, Dogaru Gabriela B, Alexescu Teodora G, Milaciu Mircea V, Saraci George V, Macarie Antonia E, Para Ioana   +9 more
doaj   +1 more source

Active site loop conformation regulates promiscuous activity in a lactonase from Geobacillus kaustophilus HTA426.

PLoS ONE, 2015
Enzyme promiscuity is a prerequisite for fast divergent evolution of biocatalysts. A phosphotriesterase-like lactonase (PLL) from Geobacillus kaustophilus HTA426 (GkaP) exhibits main lactonase and promiscuous phosphotriesterase activities.
Yu Zhang, Jiao An, Guang-Yu Yang, Aixi Bai, Baisong Zheng, Zhiyong Lou, Geng Wu, Wei Ye, Hai-Feng Chen, Yan Feng, Giuseppe Manco   +10 more
doaj   +1 more source