Results 71 to 80 of about 6,201 (226)

Statins in Breast Cancer Therapy: Mechanistic Insights and Emerging Evidence

Cancer Innovation, Volume 5, Issue 1, February 2026.
Statins, particularly simvastatin, demonstrate potential as adjuvant agents in breast cancer treatment by disrupting tumour cell signalling and survival pathways. This review highlights emerging evidence supporting their repurposing for improved outcomes, especially in aggressive breast cancer subtypes.
Rohina Alim, H. M. Kasuni Akalanka
wiley   +1 more source

Biofunctionalization of Silver Nanoparticles With Lactonase Leads to Altered Antimicrobial and Cytotoxic Properties

Frontiers in Molecular Biosciences, 2019
Background: N-acylated homoserine lactone lactonase which cleave the Acyl homoserine lactone molecules produced by biofilm-forming pathogens and silver nano-particles (AgNPs), are known for their antibacterial effect against several Gram-positive and ...
Kshitiz Gupta, Sanjay Chhibber
doaj   +1 more source

Deciphering Pigmented Rice Varieties as Sustainable and Unexplored Valuable Sources of Bioactive Components With Health‐Related Properties and Technological Applications—A Systematic Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT The interest in pigmented grains has grown substantially in recent years. Pigmented rice is crucial for diversifying agricultural production and promoting healthier, more balanced diets. This systematic review updates and discusses literature published between 2019 and 2024 on the bioactive compounds in pigmented rice, their potential health ...
Adolfo Pinheiro de Oliveira, Thatyane Mariano Rodrigues de Albuquerque, Evandro Leite de Souza   +2 more
wiley   +1 more source

Enzymes with Lactonase Activity against Fungal Quorum Molecules as Effective Antifungals

Biomolecules
Since the growing number of fungi resistant to the fungicides used is becoming a serious threat to human health, animals, and crops, there is a need to find other effective approaches in the eco-friendly suppression of fungal growth.
Elena Efremenko, Aysel Aslanli, Maksim Domnin, Nikolay Stepanov, Olga Senko   +4 more
doaj   +1 more source

New PON1-based biosensor for the detection of homocysteine-thiolactone in human plasma [PDF]

, 2015
Poster presented at the XXIII International Symposium on Bioelectrochemistry and Bioenergetics, 14-18 June 2015, Malmo ...
Almeida, M. Gabriela, Monteiro, Tiago, Oliveira, Francisco, Pereira, Sofia A., Silveira, Célia M.   +4 more
core  

Purification and characterisation of a quorum quenching AHL-lactonase from the endophytic bacterium Enterobacter sp. CS66. [PDF]

, 2018
The quorum quenching (QQ) activity of endophytic bacteria associated with medicinal plants was explored. Extracts of the Gram-negative Enterobacter sp. CS66 possessed potent N-acylhomoserine lactone (AHL) hydrolytic activity in vitro.
Abdelhamid, Yassmin, Dolan, Stephen K, Shastry, Rajesh Padumane, Vittal, Ravishankar Rai, Welch, Martin   +4 more
core   +1 more source

Genomic and Phenotypic Bases of Salt Tolerance in Sinorhizobium meliloti: Candidate Traits for Bioinoculant Development Addressing Saline Soils

Microbial Biotechnology, Volume 19, Issue 1, January 2026.
Genome‐wide association analysis on 49 Sinorhizobium meliloti strains (21 de novo sequenced) reveals extensive phenotypic heterogeneity in salt tolerance, closely associated with quorum sensing, cell surface stability and adaptation. Salt‐tolerant strains exhibit a wider metabolic capacity, especially in carbon sources exploitation, underscoring their ...
Agnese Bellabarba, Camilla Fagorzi, Giovanni Bacci, Francesca Decorosi, Alice Checcucci, Gaio Cesare Pacini, Abdelkader Bekki, Amina El Hadj Mimoune, Khalid Azim, Majida Hafidi, Alessio Mengoni, Francesco Pini, Carlo Viti   +12 more
wiley   +1 more source

Molecular Mechanisms of Plant Growth–Promoting Rhizobacteria (PGPR) in Biofertilization and Disease Suppression of Crops

International Journal of Agronomy, Volume 2026, Issue 1, 2026.
Plant growth–promoting rhizobacteria (PGPR) are beneficial soil bacteria that colonize the rhizosphere and enhance plant growth through direct and indirect mechanisms, including nutrient solubilization, phytohormone production, suppression of phytopathogens, and activation of plant defense mechanisms.
Etsay Mesele, Gebremedhin Gebreslassie, Ashenafi Teklay Yaekob, Tesfakiros Semere, Maria Serrano   +4 more
wiley   +1 more source

Quorum Quenching Lactonase Strengthens Bacteriophage and Antibiotic Arsenal Against Pseudomonas aeruginosa Clinical Isolates

Frontiers in Microbiology, 2019
Many bacteria use quorum sensing (QS), a bacterial communication system based on the diffusion and perception of small signaling molecules, to synchronize their behavior in a cell-density dependent manner.
Sonia Mion, Benjamin Rémy, Benjamin Rémy, Laure Plener, Fabienne Brégeon, Fabienne Brégeon, Eric Chabrière, David Daudé   +7 more
doaj   +1 more source

Omics Analysis of Lignin Degradation by the Gut Microbiomes of Wood‐Eating Hypomeces squamosus Fabricius

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
(1) The dominant lignin‐degrading genus taxon was Pantoea. (2) The key genes MHS‐HN_11398_2 (protocatechuate 2,3‐dioxygenase) and MHS‐HN_4821_1 (muconolactone d‐isomerase) were identified. (3) Three degrading pathways, ortho‐cleavage and meta‐cleavage of catechol, and ring‐opening of protocatechuate, were found. ABSTRACT Microbial degradation of lignin
Chunlan Mao, Qing Zhang, Jing Zhang, Xiangkai Li   +3 more
wiley   +1 more source