Structural and Biochemical Characterization of AidC, a Quorum-Quenching Lactonase With Atypical Selectivity [PDF]
, 2015 Quorum-quenching catalysts are of interest for potential application as biochemical tools for interrogating interbacterial communication pathways, as antibiofouling agents, and as anti-infective agents in plants and animals.
Fast, Walter +6 more
core +2 more sources
AhlX, an N-acylhomoserine Lactonase with Unique Properties [PDF]
Marine Drugs, 2019 N-Acylhomoserine lactonase degrades the lactone ring of N-acylhomoserine lactones (AHLs) and has been widely suggested as a promising candidate for use in bacterial disease control. While a number of AHL lactonases have been characterized, none of them has been developed as a commercially available enzymatic product for in vitro AHL quenching due to ...
Pengfu Liu +8 more
openaire +3 more sources
Modulation of paraoxonase 1 and 3 expression after moderate exercise training in the rat
Journal of Lipid Research, 2009 Paraoxonases (PONs) are a small family of antioxidant enzymes whose antiatherogenic activity is well known. The aim of the present study was the evaluation of the effects of moderate aerobic training on their expression using a rat model.
Rita Romani +8 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 IntroductionBurkholderia thailandensis is a study model for Burkholderia pseudomallei, a highly virulent pathogen, known to be the causative agent of melioidosis and a potential bioterrorism agent.
Mélanie Gonzales +6 more
doaj +1 more source
\u3cem\u3eArabidopsis thaliana\u3c/em\u3e GLX2-1 Contains a Dinuclear Metal Binding Site, but Is Not a Glyoxalase 2 [PDF]
, 2009 In an effort to probe the structure and function of a predicted mitochondrial glyoxalase 2, GLX2-1, from Arabidopsis thaliana, GLX2-1 was cloned, overexpressed, purified and characterized using metal analyses, kinetics, and UV–visible, EPR, and 1H-NMR ...
Bennett, Brian +3 more
core +2 more sources
Microbiology Spectrum, 2022 Quorum sensing (QS) is a cell-density-dependent, intercellular communication system mediated by small diffusible signaling molecules. QS regulates a range of bacterial behaviors, including biofilm formation, virulence, drug resistance mechanisms, and ...
Rakesh Sikdar, Mikael H. Elias
doaj +1 more source
The symbiotic biofilm of Sinorhizobium fredii SMH12, necessary for successful colonization and symbiosis of glycine max cv osumi, is regulated by quorum sensing systems and inducing Flavonoids via NodD1 [PDF]
, 2014 Bacterial surface components, especially exopolysaccharides, in combination with bacterial Quorum Sensing signals are crucial for the formation of biofilms in most species studied so far.
Baena Ropero, Irene +8 more
core +1 more source
Effects of Signal Disruption Depends on the Substrate Preference of the Lactonase
Frontiers in Microbiology, 2020 Many bacteria produce and use extracellular signaling molecules such as acyl homoserine lactones (AHLs) to communicate and coordinate behavior in a cell-density dependent manner, via a communication system called quorum sensing (QS).
Kathleen Mahan +6 more
doaj +1 more source
Biotechnological applications of functional metagenomics in the food and pharmaceutical industries [PDF]
, 2015 peer-reviewedMicroorganisms are found throughout nature, thriving in a vast range of environmental conditions. The majority of them are unculturable or difficult to culture by traditional methods.
Alvarez-Ordonez, Avelino +3 more
core +1 more source
Differential active site loop conformations mediate promiscuous activities in the lactonase SsoPox.
PLoS ONE, 2013 Enzymes are proficient catalysts that enable fast rates of Michaelis-complex formation, the chemical step and products release. These different steps may require different conformational states of the active site that have distinct binding properties ...
Julien Hiblot +3 more
doaj +1 more source