Results 51 to 60 of about 6,139 (211)

Harnessing hyperthermostable lactonase from Sulfolobus solfataricus for biotechnological applications [PDF]

Scientific Reports, 2016
AbstractExtremozymes have gained considerable interest as they could meet industrial requirements. Among these, SsoPox is a hyperthermostable enzyme isolated from the archaeon Sulfolobus solfataricus. This enzyme is a lactonase catalyzing the hydrolysis of acyl-homoserine lactones; these molecules are involved in Gram-negative bacterial communication ...
Remy, Benjamin, Plener, Laure, Poirier, Laetitia, Elias, Mikael, Daudé, David, Chabriere, Eric   +5 more
openaire   +3 more sources

Enterobacter Species: Opportunistic Human and Plant Pathogens With Plant‐Beneficial Traits

Molecular Plant Pathology, Volume 27, Issue 3, March 2026.
The pathogen profile on Enterobacter species synthesises current knowledge on host range, disease symptoms, plant‐beneficial traits and compares genomic features within the genus. ABSTRACT Enterobacter species occur across diverse habitats and are best known for causing opportunistic and nosocomial infections in humans.
Sara Jordan, Pieter de Maayer, Theo H. M. Smits, Teresa A. Coutinho   +3 more
wiley   +1 more source

Cloning, Expression And Characterization Of Ahlinactivating aiiA Gene Homologue In Escherichia coli [PDF]

, 2014
Cell-to-cell communication pathway of single-celled microbes is usually coordinated by quorum sensing (QS) system mediated by signal molecules. This cell density-dependent system plays a vital role in functional coordination of most pathogenic ...
Subashini, Muniandy
core  

PvdQ Quorum Quenching Acylase Attenuates Pseudomonas aeruginosa Virulence in a Mouse Model of Pulmonary Infection [PDF]

, 2018
Pseudomonas aeruginosa is the predominant pathogen in pulmonary infections associated with cystic fibrosis. Quorum sensing (QS) systems regulate the production of virulence factors and play an important role in the establishment of successful P ...
Melgert, Barbro N., Quax, Wim J., Setroikromo, Rita, Utari, Putri D.   +3 more
core   +3 more sources

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, Volume 13, Issue 10, 18 February 2026.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

Enzymes with Lactonase Activity against Fungal Quorum Molecules as Effective Antifungals

Biomolecules
Since the growing number of fungi resistant to the fungicides used is becoming a serious threat to human health, animals, and crops, there is a need to find other effective approaches in the eco-friendly suppression of fungal growth.
Elena Efremenko, Aysel Aslanli, Maksim Domnin, Nikolay Stepanov, Olga Senko   +4 more
doaj   +1 more source

Effect of β-lactamase inhibitors on in vitro activity of β-lactam antibiotics against Burkholderia cepacia complex species [PDF]

, 2016
Background: Bacteria belonging to the Burkholderia cepacia complex (Bcc) are an important cause of chronic respiratory tract infections in cystic fibrosis patients. Intrinsic resistance to a wide range of antimicrobial agents, including a variety of beta-
Coenye, Tom, Everaert, Annelien
core   +2 more sources

Statins in Breast Cancer Therapy: Mechanistic Insights and Emerging Evidence

Cancer Innovation, Volume 5, Issue 1, February 2026.
Statins, particularly simvastatin, demonstrate potential as adjuvant agents in breast cancer treatment by disrupting tumour cell signalling and survival pathways. This review highlights emerging evidence supporting their repurposing for improved outcomes, especially in aggressive breast cancer subtypes.
Rohina Alim, H. M. Kasuni Akalanka
wiley   +1 more source

Multiple Quorum Quenching Enzymes Are Active in the Nosocomial Pathogen Acinetobacter baumannii ATCC17978

Frontiers in Cellular and Infection Microbiology, 2018
Acinetobacter baumannii presents a typical luxI/luxR quorum sensing (QS) system (abaI/abaR) but the acyl-homoserine lactone (AHL) signal profile and factors controlling the production of QS signals in this species have not been determined yet.
Celia Mayer, Andrea Muras, Manuel Romero, María López, María Tomás, Ana Otero   +5 more
doaj   +1 more source

Bacterial Quorum-Quenching Lactonase Hydrolyzes Fungal Mycotoxin and Reduces Pathogenicity of Penicillium expansum—Suggesting a Mechanism of Bacterial Antagonism

Journal of Fungi, 2021
Penicillium expansum is a necrotrophic wound fungal pathogen that secrets virulence factors to kill host cells including cell wall degrading enzymes (CWDEs), proteases, and mycotoxins such as patulin. During the interaction between P.
Shlomit Dor, Dov Prusky, Livnat Afriat-Jurnou   +2 more
doaj   +1 more source