Results 181 to 190 of about 95,231 (345)

Chemoenzymatic Route toward a De Novo Enantioselective Total Synthesis of (S)‐Baclofen Based on Metal‐Catalyzed Hydroformylation and Enzymatic Transamination

open access: yesChemBioChem, EarlyView.
A unique chemoenzymatic synthesis route toward (S)‐baclofen is presented, which highlights a hydroformylation and biocatalysis step toward the synthesis of such a challenging β‐chiral amino acid. The shown methodology exhibits high conversions and enantiomeric excess and is transferable to other β‐chiral amines and amino acids.
Feodor Belov   +6 more
wiley   +1 more source

Synthesis of a Lactone [PDF]

open access: yesJournal of Chemical Education, 1998
openaire   +2 more sources

Diastereoselective, Diversifiable Synthesis and Biological Evaluation of the Virginiamycin Inducers, the Virginiae Butanolides

open access: yesChemBioChem, EarlyView.
Production of natural products is tightly regulated, resulting in many silent biosynthetic gene clusters. BarA is a repressor that downregulates production of the virginiamycin antibiotics. The VBs are ligands for BarA that reverse its repression of virginiamycin production.
Kylie G. Castator   +3 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

From Biomass to Polymers: Kinetic Analysis and Sustainable Synthesis of Lignin‐Polycaprolactone Copolymers

open access: yesChemCatChem, EarlyView.
Lignin‐polycaprolactone (PCL) copolymers were prepared using a highly efficient and nontoxic zinc catalyst. The reaction kinetics were investigated and differ from those usually observed in ring‐opening polymerization. Depending on the chain length of the copolymer, an acceleration of the reaction was found.
Tim Langletz   +3 more
wiley   +1 more source

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