Results 171 to 180 of about 76,516 (303)

Enantioselective Synthesis of Spirolactones and Spirolactams Under Low Catalyst Loadings. [PDF]

J Am Chem Soc
Saito T, Navarro A, Davies HML.
europepmc   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Antifungal Activity of Four Medium-Chain Fatty Acids and γ-Undecalactone Against <i>Candida albicans</i>. [PDF]

Curr Issues Mol Biol
Yoshida M, Terada H, Hayashi S, Haraguchi T, Watanabe M, Yamashita M, Yoshii M, Hatanaka Y, Nagao T.   +8 more
europepmc   +1 more source

Patch Test Results With the European Baseline Series, 2021/2022—Joint European Results of the ESSCAA and the EBSB Working Groups of the ESCD, and the GEIDACC

Contact Dermatitis, EarlyView.
ABSTRACT Background Patch test results obtained with the European Baseline Series (EBS) in its current version serve both contact allergy surveillance and (re‐)assessing the diagnostic value of EBS allergens. Objectives To present results of current EBS patch testing, obtained in 59 departments in 14 European countries during 2021 and 2022.
Wolfgang Uter, S. Mark Wilkinson, Olivier Aerts, Andrea Bauer, Leopoldo Borrego, Richard Brans, Timo Buhl, Heinrich Dickel, Aleksandra Dugonik, Francesca Larese Filon, Ana Giménez Arnau, Cataldo Patruno, Györgyi Pónyai, Stamatis Gregoriou, Steffen Schubert, Dagmar Simon, Luca Stingeni, Skaidra Valiukevičienė, Elke Weisshaar, Thomas Werfel, Margarida Gonçalo, Marie‐L. A. Schuttelaar, ESSCAA and EBSB ESCD Working Groups, and the GEIDACC, Birger Kränke, Alexander Navarini, Philip Spring, Ulrike Beiteke, Cecilia Dietrich, Sibylle Schliemann, Detlef Becker, Swen Malte John, Nicola Wagner, Dimitra Koumaki, Maddalena Napolitano, Anna Belloni Fortina, Francesca Larese Filon, Rosella Gallo, Thomas Rustemeyer, Radoslaw Spiewak, Maja Kalac Pandurovic, Tanja Kmecl, Mojca Simončič Godnič, Nada Kecelj, Philippa Cousen, Ella Dendooven, Juan Francisco Silvestre Salvador, José Manuel Carrascosa Carrillo, Mónica Munera Campos, Esther Serra Baldrich, Gemma Melé‐Ninot, Cristina Barrabés Torrella, David Pesqué, María Antonia Pastor Nieto, Francisco Navarro Triviño, Inmaculada Ruiz Gonzales, Enrique Gómez de la Fuente, Susana Córdoba Guijarro, Francisco Javier Ortiz de Frutos, Fátima Tous Romero, Tatiana Sanz Sánchez, Pablo Chicharro Manso, Marta Andreu Barasoain, Marta Elosua González, Araceli Sánchez Gilo, Paloma Sánchez‐Pedreño Guillén, Pedro Mercader‐García, Carmen Paredes Suárez, María Elena Gatica Ortega, José Juan Pereyra Rodríguez, Javier Miquel Miquel, Mercedes Rodríguez Serna, Violeta Zaragoza Ninet, Ricardo González Pérez   +73 more
wiley   +1 more source

The Approximate Subcutaneous LD₅₀ and Associated Lesions Induced by Ivalin, Extracted and Purified from <i>Geigeria aspera</i> Harv., in Sprague-Dawley Rats. [PDF]

Molecules
Locke S, Botha C, Clift S, Lensink A.
europepmc   +1 more source

Patch Testing in Individuals With Diabetes Using Medical Devices. Part 2—Contact Allergy to Medical Device Allergens and New Patch Test Recommendations

Contact Dermatitis, EarlyView.
This study aimed to describe the prevalence of contact allergy to allergens found in diabetes medical devices (MDs) among diabetes MD users and suggest an updated MD patch test series. Of the 204 diabetes MD users (114 with skin rash to diabetes MDs and 90 without), 16.2% were positive to allergens found in diabetes MDs, which underlines the urgent ...
Josefin Ulriksdotter, Martin Mowitz, Thanisorn Sukakul, Magnus Bruze, Nils Hamnerius, Cecilia Svedman   +5 more
wiley   +1 more source

Desymmetrization of Malonic Monoesters and Malonic Acids via Enantioselective Catalytic C(sp³)─H Oxidation. [PDF]

Angew Chem Int Ed Engl
Siakavaras N, Call A, Bietti M, Costas M.   +3 more
europepmc   +1 more source

Contact Sensitization in Patients With Frontal Fibrosing Alopecia: Patch Test Results With an Extended Baseline Series in Consecutive Patients

Contact Dermatitis, EarlyView.
Sensitization to propolis, shellac and gallate mix is FFA‐associated, but its relevance is largely unknown. Sensitization to salicylates is frequent and associated with symptoms of intolerance to sun exposure or sunscreens. No significant improvement by allergen avoidance is identified.
María‐Antonia Pastor‐Nieto, María Elena Gatica Ortega, Anna María Giménez‐Arnau, Tatiana Sanz‐Sánchez, Pedro Mercader García, Inmaculada Ruíz‐González, Gemma Melé‐Ninot, Pablo Chicharro, Paloma Sánchez‐Pedreño, Marina de Vega, Miguel Ángel Gallego Descalzo, Leopoldo Borrego   +11 more
wiley   +1 more source

Novel DAG-Lactone-Based Vav1 Inhibitors Show Anti-proliferative Activity in Pancreatic Cancer Models. [PDF]

ChemMedChem
Bellomo A, Toruner M, Elhalem E, Peach ML, Gandolfi Donadío L, Giordano L, Hogenson TL, Fernandez-Zapico ME, Comin MJ.   +8 more
europepmc   +1 more source

Bacterial quorum sensing peptides and the inter-kingdom communication with human cancer cells [PDF]

, 2016
De Spiegeleer, Bart, Janssens, Yorick, Verbeke, Frederick, Wynendaele, Evelien   +3 more
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