Results 181 to 190 of about 26,944 (259)

Synthesis of 5,5,6-Fused Tricyclic Lactones: Stereocontrol of Three Consecutive Stereocenters. [PDF]

Org Lett
Ziari A, Císařová I, Matoušová E.
europepmc   +1 more source

S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea

The FEBS Journal, EarlyView.
S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels, Michael K. F. Mohr, Phillip Nußbaum, Marie Joest, Bianca Wassmer, Laurent Rasquin, Sonja‐Verena Albers, Jennifer N. Andexer   +7 more
wiley   +1 more source

Phytochemical Composition and Overall Taste Modulation in Lettuce: Combination of Cultivar and Biofertiliser. [PDF]

Plants (Basel)
Stojanović M, Milosavljević D, Delcourt A, Hilbert JL, Hance P, Maksimović V, Dragišić Maksimović J.   +6 more
europepmc   +1 more source

Dietary modulation of antimicrobial peptides (HAMP and LEAP2) in Chinook salmon (Oncorhynchus tshawytscha) fed a phytobiotic functional diet: Integrated genomic characterisation and tissue‐specific expression

Journal of Fish Biology, EarlyView.
Abstract Antimicrobial peptides (AMPs) are key components of the innate immune system in fish, providing rapid protection against microbial pathogens. Among these, the liver‐expressed antimicrobial peptides (LEAPs), comprising LEAP‐1 (hepcidin; HAMP) and LEAP‐2, play central roles in host defence and iron regulation.
Roberta Marcoli, Jane E. Symonds, Seumas P. Walker, Cesar Lopez, Mark A. Preece, Christopher Battershill, Steve Bird   +6 more
wiley   +1 more source

Structural Diversification of 14-Membered Macrolides by Chemoenzymatic Synthesis. [PDF]

JACS Au
Curtis BJ, Boesger HA, Schmidt JJ, Adrover-Castellano ML, Momin AN, Glasser CA, Sherman DH.   +6 more
europepmc   +1 more source

Diagnosis and Off‐Label Treatment of Subcutaneous Putative Dracunculoid Nematodes in Apteronotus albifrons Originating From Wild‐Caught Fisheries

Journal of Fish Diseases, EarlyView.
ABSTRACT Apteronotus albifrons (Gymnotiformes: Apteronotidae), commonly known as the black ghost knifefish, is a high‐value ornamental fish that is susceptible to various parasites. The affected fish were wild‐caught fisheries and subsequently introduced into a commercial breeding system.
Pedro Henrique Magalhães Cardoso, Simone de Carvalho Balian, Herbert Sousa Soares, Marcelo Bahia Labruna, Gracienhe Gomes dos Santos, José Blanchard Girão Ribeiro Filho, Mauricio Laterça Martins   +6 more
wiley   +1 more source

Copper-Catalyzed Asymmetric Amino Lactonization of Alkenes: Direct Access to Enantioenriched 1,2-Alkylamino Alcohol Derivatives. [PDF]

J Am Chem Soc
Feng G, Hemric BN, Velopolcek M, Liu C, Wang Q.   +4 more
europepmc   +1 more source

Genomic variation drives plant flavor diversification

Journal of Integrative Plant Biology, EarlyView.
This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu, Yanwei Hao, Yiwei Zhou, Xia Zhang, Rui Xia, Pan Liao   +5 more
wiley   +1 more source

Electrochemical control enables high-concentration, one-pot macrolactonization. [PDF]

Chem Sci
Mao S, Wei D, Xu K, Zeng C.
europepmc   +1 more source

Pharmacokinetics of Moxidectin in Bare‐Nosed Wombats (Vombatus ursinus) After Intravenous, Sub‐Cutaneous and Transdermal Administration

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The anti‐parasitic drug moxidectin is a frontline treatment for sarcoptic mange in bare‐nosed wombats (Vombatus ursinus), a disease causing significant animal welfare issues and instances of local population declines. Despite widespread usage, knowledge of species‐specific pharmacokinetics of moxidectin in bare‐nosed wombats is still limited ...
E. K. Stott, L. F. Skerratt, T. Whittem, M. Leeming, K. Pillay, G. S. Doran, B. Gardner, M. Lynch, M. Klein, P. Holz, T. Chen, J. Hufschmid, A. P. Woodward   +12 more
wiley   +1 more source