Results 161 to 170 of about 76,516 (303)

Correction: Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cells. [PDF]

PLoS One
Lohberger B, Rinner B, Stuendl N, Kaltenegger H, Steinecker-Frohnwieser B, Bernhart E, Rad EB, Weinberg AM, Leithner A, Bauer R, Kretschmer N.   +10 more
europepmc   +1 more source

CRISPR/Cas9 Genome Engineering in Non‐Conventional Oleaginous Yeasts: Applications, Challenges, and Prospects

Yeast, EarlyView.
ABSTRACT Given the biotechnological potential of yeast‐derived oils for oleochemical production, genes encoding lipid metabolism enzymes are key targets for metabolic engineering. Genetic engineering tools such as Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9, Transcription Activator‐Like Effector Nucleases (TALENs), Zinc ...
Rodrigo Gonçalves Dias, Fernanda Pinheiro Moreira Freitas, Eduardo Luís Menezes de Almeida, Luciano Gomes Fietto, Agustin Zsögön, Wendel Batista da Silveira   +5 more
wiley   +1 more source

Dynamic Enantioconvergent Desaturation of 4,5-Disubstituted γ-Lactones in Whole Cells of <i>Rhodococcus erythropolis</i>. [PDF]

J Am Chem Soc
Cancellieri MC, Boratyński F, Serra S, Hernik D, Gatti FG.   +4 more
europepmc   +1 more source

Root exudates mediate microorganisms to improve rhizosphere nutrient availability and crop productivity under straw mulching and slow‐release nitrogen fertilizer

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Root exudates play a key role as signals and nutrients in mediating plant–microbe communication. However, critical knowledge gaps remain regarding how root exudates mediate soil–microbe–plant interactions to regulate crop yield under long‐term straw mulching combined ...
Jiajie Song, Shahzad Haider, Jianheng Song, Dingding Zhang, Gaihe Yang, Guangxin Ren, Xing Wang, Yongzhong Feng   +7 more
wiley   +1 more source

Sesquiterpene lactones in micropropagated Arnica montana shoots after elicitation-insights into metabolite accumulation and transcriptional regulation. [PDF]

Sci Rep
Sozoniuk M, Trendafilova A, Mishev K, Geneva M, Miladinova-Georgieva K, Ivanova V, Dimitrova L, Dimitrova M, Petrova M.   +8 more
europepmc   +1 more source

Anthelmintic resistance in sheep nematodes in Australia: a compilation of recent test results

Australian Veterinary Journal, EarlyView.
Objective The results of recent faecal egg count reduction tests (FECRTs) were collated to provide an indication of the prevalence and severity of anthelmintic resistance in sheep nematodes across Australia and of changes in comparison to earlier testing reports.
RB Besier, NM Rolls
wiley   +1 more source

Hyptolactones and Their Biological Potential: A Systematic Review. [PDF]

J Nat Prod
Julião FGH, da Silva JA.
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

In Vitro Evaluation of Natural Sesquiterpene Lactones and Naphthoquinones Against Pancreatic Ductal Adenocarcinoma Cells. [PDF]

Molecules
Mirakian NT, Iácono RF, Pulido VB, Pibuel MA, Lompardía SL, Laurella LC, Pérez-Mauad N, Catalán CAN, Lombardo T, Ledesma MM, Carlucci A, Sülsen VP, Papademetrio DL.   +12 more
europepmc   +1 more source

Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways

British Journal of Pharmacology, EarlyView.
Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck, Mario van der Stelt   +1 more
wiley   +1 more source