Results 241 to 250 of about 98,587 (340)

Isolation and characterization of two 16-membered lactones: 20-deoxorosaramicin and 20-deoxo-12,13-desepoxy-12,13-dehydrorosaramicin aglycones, from a mutant strain of Micromonospora rosaria.

, 1982
Richard W. Vaughan, Jason Lotvin, Mohindar S. Puar, Mahesh Patel, Allan Kershner, M. G. Kalyanpur, JOSEPH A. MARQUEZ, J. Allan Waitz   +7 more
openalex   +2 more sources

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl, Mies Bethäuser, Daniela Nürnberger, Stefan Oswald, Andreas Moritz, Melanie Hamann, Joachim Geyer   +6 more
wiley   +1 more source

Modular esterification of unstrained carbonyls through palladium-catalyzed alkyne bridging C-C bond activation. [PDF]

Nat Commun
Ding M, Niu M, Hu L, Guan Q, Yuan S, Yu Y, Xiao M, Huang S, Lu G, Huang X.   +9 more
europepmc   +1 more source

On the Reactions of 4-Membered Lactones and Amines

, 1951
Yoshio Iwakura, Kuniji Nagakubo, Haruo Kawasumi, Sukeyasu Kigawa   +3 more
openalex   +2 more sources

Jasmonate‐Activated AaWRKY9–AabHLH93/AabHLH93–AaMYB7 Complexes Balance Artemisinin Biosynthesis in Artemisia annua

Plant Biotechnology Journal, EarlyView.
ABSTRACT Artemisinin, an antimalarial sesquiterpene lactone, is biosynthesized in glandular trichomes of Artemisia annua. Although numerous transcription factors have been demonstrated to regulate artemisinin biosynthesis, the molecular mechanisms underlying the high expression of artemisinin‐associated biosynthetic enzyme and transcription factor ...
Xueqing Fu, Han Zheng, Yaojie Zhang, Muyao Yu, Shu Li, Hang Liu, Pin Liu, Ling Li, Xiaofen Sun, Jingya Zhao, Yuliang Wang, Kexuan Tang   +11 more
wiley   +1 more source

The economic impact of endo- and ectoparasites in dairy cattle. [PDF]

Parasit Vectors
Strydom T, Lavan RP, Torres S, Pinilla JC.   +3 more
europepmc   +1 more source

The use of 'pi'-allyltricarbonyliron lactone complexes in organic synthesis

, 1995
Graham Meek
openalex   +1 more source

Mass Spectrometry Imaging Combined With Single‐Cell Transcriptional Profiling Reveals the Multidimensional Spatial Distributions and Biosynthetic Pathways of Medicinal Components in Andrographis paniculata

Plant Biotechnology Journal, EarlyView.
ABSTRACT The synthesis and accumulation of active ingredients in medicinal plants are distributed in specific organs, tissues, and cell types, which are important for the exploitation of medicinal plants. However, the fine distribution of active ingredients is difficult to know. Here, the system of mass spectrometry imaging (MSI) integrated with single‐
HaiSheng Zeng, MeiHui Shi, ZhiRong Chen, XueJing Sun, HuiJie Zhang, Yue Huang, YuCheng Chen, Jun Ren, HuiLing Huang, Almaz Borjigidai, Man Zhang, SuJuan Duan, Yi‐Jun Chen, Hong‐Lei Jin, Hong‐Bin Wang   +14 more
wiley   +1 more source

A new paradigm for valorization of waste poly(glycolic acid): facile coupling with epoxides and synthesis of copolyesters with enhanced performance. [PDF]

Chem Sci
Ren F, Liang Z, Jia Y, Li B, Sun Z, Hu C, Pang X, Chen X.   +7 more
europepmc   +1 more source

Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum

Plant Biotechnology Journal, EarlyView.
ABSTRACT Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of diosgenin biosynthesis could enhance its production.
Jongbu Lim, Keunhwa Kim, Jung Heo, Seung Mo Seo, Sungjun Choung, Hyeonjin Kim, Yuri Choi, Kyungsun Park, Hyejung Yun, Dongha Kim, Eun Song Lee, Junwoo Lee, Smita Mirsyad Warsadiharja, Saet Buyl Lee, Sunkyu Han, Soon Ju Park, Sang‐Gyu Kim   +16 more
wiley   +1 more source