Results 211 to 220 of about 5,526 (234)

Global Profiling of Lactylation Proteomics and Specific Lactylated Site Validation in Rheumatoid Arthritis Patients

Journal of Proteome Research
Protein lactylation is a novel post-translational modification that has rarely been investigated in rheumatoid arthritis (RA). This study aimed to explore lactylation proteomics in RA patients and validate sorted candidate lactylation sites. Synovial tissues from ten RA and six osteoarthritis (OA) patients were subjected to lactylation proteomics via ...
Jiaqi Hu, Zhengyi Jin, Ying Gao, Qilong Liu, Yiyi Yu, Ruina Kong, Dongbao Zhao, Jie Gao   +7 more
openaire   +2 more sources

The role of lactylation in virology

Virology
Lactylation, a novel post-translational protein modification, is increasingly recognized for its widespread occurrence on lysine residues in both histone and non-histone proteins. Recent research has primarily focused on its implications in specific human diseases, particularly cancer progression, metabolic disorders, neurodegenerative diseases, and ...
Sirui Wang, Leiliang Zhang
openaire   +2 more sources

Both L-lactyl and D-lactyl enantiomers modify histones in mouse testis

Abstract Dynamic histone post-translational modifications are crucial to precisely orchestrate gene expression programs. The recently discovered histone lysine lactylation has already been explored in various pathological contexts, but less in normal tissues.
Julie Manessier, Hassan Hijazi, Sabine Brugière, Marie Courçon, Christophe Masselon, Alberto de la Iglesia, Julie Cocquet, Delphine Pflieger   +7 more
openaire   +1 more source

KDM6B-Mediated HADHA Demethylation/Lactylation Regulates Cementogenesis

Journal of Dental Research
Cementum, a bone-like tissue, is an essential component of periodontium, and periodontitis can lead to degenerative changes in the cementum, eventually resulting in tooth loss. The therapeutic strategy for advanced periodontitis is to achieve periodontal regeneration, of which cementum regeneration is a key criterion. Cementoblasts are responsible for
Z. Yang, H. Wang, J. Xiao, Q. Yang, J. Sun, H. Liu, L. Ma, X. Huang, C. Wang, X. Wang, Z. Cao   +10 more
openaire   +2 more sources

lactyl, n.

2023
openaire   +1 more source

Efficient synthesis of lactylated histone peptides enabled by a pre-prepared protected lactylated-lysine

Tetrahedron Letters, 2023
Qingyao Shu, Jian Fan, Bingji Wang, Jing Shi   +3 more
openaire   +1 more source

Lactylation constrains OXPHOS under hypoxia

Cell Research
Haowen Ren, Di Zhang
openaire   +2 more sources

Role of TFEB lactylation

Nature Cell Biology
openaire   +2 more sources

Myristoyl Lactylic Acid

2007
openaire   +1 more source

Sodium Cocoyl Lactylate

2007
openaire   +1 more source