Results 71 to 80 of about 17,219,459 (310)
Frontiers in Immunology, 2023 Background Immune cell expression profiling from patient samples is critical for the successful development of immuno-oncology agents and is useful to understand mechanism-of-action, to identify exploratory biomarkers predictive of response, and to guide
Bradley Garman +13 more
semanticscholar +1 more source
Cutting-Edge: Preclinical and Clinical Development of the First Approved Lag-3 Inhibitor
Cells, 2022 Immune checkpoint inhibitors (ICIs) have revolutionized medical practice in oncology since the FDA approval of the first ICI 11 years ago. In light of this, Lymphocyte-Activation Gene 3 (LAG-3) is one of the most important next-generation immune ...
L. Chocarro +11 more
semanticscholar +1 more source
TIM-3 expression in breast cancer
OncoImmunology, 2018 Tumor-infiltrating lymphocytes (TILs) are predominantly present in breast cancer patients with estrogen receptor negative tumors, among whom increasing levels correlate with favorable outcomes.
Samantha Burugu +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu +20 more
wiley +1 more source
Cancers, 2021 Simple Summary Patients with chronic lymphocytic leukemia (CLL), the most frequent B cell malignancy in western countries, develop a progressive immunosuppression, leading to diminished anti-tumor immunity.
Christian Sordo-Bahamonde +6 more
semanticscholar +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li +9 more
wiley +1 more source
On the role of dissipating inhibition in task switching [PDF]
, 2013 The n-2 repetition cost has been explained by persisting inhibition of a previously valid task set which dissipates over time. This account has two implications, namely that the switch cost decreases with the number of tasks involved in switching and ...
Vandierendonck, André
core +1 more source
Science Translational Medicine, 2021 Peripheral blood LAG+CD8+ T cells are more commonly identified in immunotherapy-treated patients with cancer who have less favorable outcomes. Pinpointing checkpoint response Immune checkpoint inhibitors can aid the immune system of some to effectively ...
R. Shen +23 more
semanticscholar +1 more source
Expression of LAG‐3 and efficacy of combination treatment with anti‐LAG‐3 and anti‐PD‐1 monoclonal antibodies in glioblastoma [PDF]
International Journal of Cancer, 2018 Like in many tumor types, immunotherapy is currently under investigation to assess its potential efficacy in glioblastoma patients. Trials are under way to assess the efficacy of new immune checkpoint inhibitors including anti‐PD‐1 or CTLA4. We here investigate the expression and efficacy of a novel immune‐checkpoint inhibitor, called LAG‐3.
Sarah Harris‐Bookman +20 more
openaire +2 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül +2 more
wiley +1 more source