Results 31 to 40 of about 3,664 (121)

Presynaptic Paraneoplastic Disorders of the Neuromuscular Junction: An Update

open access: yesBrain Sciences, 2021
The neuromuscular junction (NMJ) is the target of a variety of immune-mediated disorders, usually classified as presynaptic and postsynaptic, according to the site of the antigenic target and consequently of the neuromuscular transmission alteration ...
Maria Pia Giannoccaro   +2 more
doaj   +1 more source

Update on treatment options for Lambert–Eaton myasthenic syndrome: focus on use of amifampridine

open access: yesNeuropsychiatric Disease and Treatment, 2011
Sabine Lindquist, Martin StangelSection Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, Hannover, GermanyAbstract: In Lambert–Eaton myasthenic syndrome (LEMS), antibodies against presynaptic ...
Lindquist S, Stangel M
doaj  

Gender issues of antibody-mediated diseases in neurology: (NMOSD/autoimmune encephalitis/MG)

open access: yesTherapeutic Advances in Neurological Disorders, 2020
Neuromyelitis optica spectrum disorder (NMOSD), autoimmune encephalitis (AE), myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) are antibody-mediated neurological diseases.
Ayse Altintas   +9 more
doaj   +1 more source

Myasthenia gravis and Lambert-Eaton myasthenic syndrome: treatment options and guidance for management during COVID-19 pandemic

open access: yesNeurologijos seminarai, 2020
Myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) are immune-mediated neurologic disorders characterized by muscle weakness and fatigue. MG is the most common neuromuscular junction disorder while LEMS is an extraordinary rare disease.
A. Klimašauskienė , R. Bunevičiūtė
doaj   +1 more source

Adenocarcinoma of Lung Presenting as Lambert-Eaton Myasthenic Syndrome

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2017
Lambert-Eaton myasthenic syndrome (LEMS) is a paraneoplastic neuromuscular junction disorder. LEMS presents with muscular weakness and fatigability, mainly involving the proximal lower limbs.
Sumera Bukhari MD   +4 more
doaj   +1 more source

Lamber-Eaton myasthenic syndrome associated with multiple myeloma: A case report

open access: yesCurrent Problems in Cancer: Case Reports
Background: Lambert-Eaton myasthenic syndrome (LEMS) is an uncommon illness of the neuromuscular junction. It typically manifests as a combination of proximal muscular weakness, autonomic dysfunction, and areflexia.
Sebastian S Casillas-Berumen   +7 more
doaj   +1 more source

Anti-CV2/CRMP5 antibody-positive paraneoplastic neurological syndromes with chronic intestinal pseudo-obstruction in a small-cell lung cancer patient: a case report and literature review

open access: yesJournal of International Medical Research, 2020
Patients with anti-CV2/collapsin response mediator protein (CRMP)5 antibodies present with more frequent chorea, cerebellar ataxia, uveo/retinal symptoms, and Lambert–Eaton myasthenic syndrome or myasthenia gravis.
Jinhua Yan   +7 more
doaj   +1 more source

Diaphragmatic Palsy Due to a Paraneoplastic Autoimmune Syndrome Revealed by Checkpoint Inhibitors

open access: yesReports
Background and Clinical Significance: Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment but may underlie diverse and potentially life-threatening immune-related adverse events (irAEs).
Jean-Baptiste Destival   +6 more
doaj   +1 more source

Pseudomyopathic Changes in Needle Electromyography in Lambert-Eaton Myasthenic Syndrome

open access: yesCase Reports in Neurological Medicine, 2013
Lambert-Eaton myasthenic syndrome (LEMS) is a rare presynaptic disorder of the neuromuscular junction in association with cancer and subsequently in cases in which no neoplasm has been detected (O’Neill et al., 1988).
Teppei Komatsu   +4 more
doaj   +1 more source

Clinical and genetic basis of congenital myasthenic syndromes

open access: yesArquivos de Neuro-Psiquiatria
Neuromuscular junction disorders represent a wide group of neurological diseases characterized by weakness, fatigability and variable degrees of appendicular, ocular and bulbar musculature involvement.
Paulo Victor Sgobbi de Souza   +5 more
doaj   +1 more source

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