Active microrheology using pulsed optical tweezers to probe viscoelasticity of Lamin A towards diagnosis of laminopathies [PDF]
, 2021 C. D. Mukherjee +4 more
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The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle
ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley +1 more source
Deciphering Nuclear Mechanobiology in Laminopathy
Cells, 2019 Extracellular mechanical stimuli are translated into biochemical signals inside the cell via mechanotransduction. The nucleus plays a critical role in mechanoregulation, which encompasses mechanosensing and mechanotransduction.
Jungwon Hah, Dong-Hwee Kim
doaj +1 more source
The effects of environmental and classroom noise on the academic attainments of primary school children [PDF]
, 2008 While at school children are exposed to various types of noise including external, environmental noise and noise generated within the classroom. Previous research has shown that noise has detrimental effects upon children?s performance at school ...
Dockrell, Julie, Shield, Bridget
core +1 more source
Food Frontiers, EarlyView.The diagram of the mechanism of action by which UroA regulates RF. ABSTRACT The global prevalence and mortality rates associated with chronic kidney disease (CKD) have been on a continuous rise over recent decades. Renal fibrosis (RF) serves as a critical factor in the progression of CKD to end‐stage renal disease.
Xue Wu +8 more
wiley +1 more source
152: Development of DNA damage foci, loss of Lamin B and activation of pp38MAPK in pPROM: classic signs of senescence in human amniochorion [PDF]
, 2014 Eryn Dutta +5 more
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Food Frontiers, EarlyView.A schematic illustration for the protective effects of AOS on OTA‐induced liver injury in mice. AOS, alginate oligosaccharides; CAT, catalase; GSTT1, glutathione S‐transferase theta 1; HO‐1, heme oxygenase 1; IκBα, inhibitor kappa B alpha; IL‐1β, interleukin‐1β; IL‐6, interleukin‐6; Keap1, kelch‐like ech‐associated protein 1; NF‐κB, nuclear factor ...
Yue Zhao +8 more
wiley +1 more source
Protein kinase C activity modulates nuclear Lamin A/C dynamics in HeLa cells
Scientific ReportsThe nuclear lamina serves important functions in the nucleus, providing structural support to the nuclear envelope and contributing to chromatin organization. The primary proteins that constitute the lamina are nuclear lamins whose functions are impacted
Chase C. Wesley +2 more
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ABHD7-mediated depalmitoylation of lamin A promotes myoblast differentiation
Cell ReportsSummary: LMNA gene mutation can cause muscular dystrophy, and post-translational modification plays a critical role in regulating its function. Here, we identify that lamin A is palmitoylated at cysteine 522, 588, and 591 residues, which are reversely ...
Yuan Shen +10 more
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Isoprenylation is required for the processing of the lamin A precursor. [PDF]
, 1990 Lawrence A. Beck +2 more
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