Results 21 to 30 of about 53,083 (269)
Role of C-Terminal Phosphorylation of Lamin A in DNA Damage and Cellular Senescence
Cells, 2023 The nuclear matrix protein lamin A is a multifunctional protein with roles in DNA replication and repair, gene activation, transcriptional regulation, and maintenance of higher-order chromatin structure. Phosphorylation is the main determinant of lamin A
Ying Ao +7 more
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bioRxiv, 2021 The ability of a cell to regulate its mechanical properties is central to its function. Emerging evidence suggests that interactions between the cell nucleus and cytoskeleton influence cell mechanics through poorly understood mechanisms.
A. Vahabikashi +15 more
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Parameters optimization of heterojunction ZnSe/CdS/CIGS/Si solar cells using SCAPS-1D software
Revue des Énergies Renouvelables, 2022 It is required to simulate the performance of a photovoltaic solar cell performance to enhance it. Simulation optimization has the benefit of being inexpensive and straightforward, and it allows us to identify the optimum parameters that contribute to ...
Moussaab Belarbi +2 more
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Neddylation modification regulates lamin B1 expression in breast cancer [PDF]
Zhongguo aizheng zazhi, 2022 Background and purpose: The role of neddylation modification in breast cancer has rarely been reported. Previous study found that neddylation modification blocking induced cellular senescence in breast cancer, however, the potential mechanism has not yet
JIA Xiaoqing, SUN Xiaoyin, JIANG Beiqi, MEI Zhangyi, FU Yun, ZHUANG Zhigang
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Frontiers in Cell and Developmental Biology, 2021 A-type lamins are the main structural components of the nucleus, which are mainly localized at the nucleus periphery. First of all, A-type lamins, together with B-type lamins and proteins of the inner nuclear membrane, form a stiff structure—the nuclear ...
A. Malashicheva, K. Perepelina
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The Dynamics of Lamin a During the Cell Cycle
Frontiers in Molecular Biosciences, 2021 Lamin proteins play an essential role in maintaining the nuclear organization and integrity; and lamin A, in particular, plays a major role in the whole volume of the nuclear interior.
Anat Vivante +3 more
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Nucleic Acids Research, 2021 Telomere maintenance is essential to preserve genomic stability and involves telomere-specific proteins, DNA replication and repair proteins. Lamins are key components of the nuclear envelope and play numerous roles, including maintenance of the nuclear ...
Gaëlle Pennarun +11 more
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Lamin A and Prelamin a Counteract Migration of Osteosarcoma Cells
Cells, 2020 A type lamins are fundamental components of the nuclear lamina. Changes in lamin A expression correlate with malignant transformation in several cancers. However, the role of lamin A has not been explored in osteosarcoma (OS).
Camilla Evangelisti +11 more
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Theoretical Investigation of Structural, Electronic, and Optical Properties of ZnSnP2 Semiconductor
Annals of West University of Timisoara: Physics, 2022 The structural, electronic, and optical properties of ZnSnP2 compound were determined using the first principles calculations. We applied the full-potential enhanced plane wave method (FP-LAPW) within the framework of density functional theory (DFT) as ...
Ouledali M. +7 more
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PCAF Involvement in Lamin A/C-HDAC2 Interplay during the Early Phase of Muscle Differentiation
Cells, 2020 Lamin A/C has been implicated in the epigenetic regulation of muscle gene expression through dynamic interaction with chromatin domains and epigenetic enzymes. We previously showed that lamin A/C interacts with histone deacetylase 2 (HDAC2).
Spartaco Santi +4 more
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