Results 21 to 30 of about 96,178 (343)
Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS
bioRxiv, 2022 In mammalian cell nuclei, the nuclear lamina (NL) underlies the nuclear envelope (NE) to maintain nuclear structure. The nuclear lamins, the major structural components of the NL, are involved in the protection against NE rupture induced by mechanical ...
Yohei Kono +7 more
semanticscholar +1 more source
Lamin B1 sequesters 53BP1 to control its recruitment to DNA damage
Science Advances, 2021 Lamin B1 controls 53BP1 recruitment to DNA damage.
Laure Etourneaud +21 more
semanticscholar +1 more source
Down-regulation of the Lamin A/C in neuroblastoma triggers the expansion of tumor initiating cells [PDF]
, 2015 Tumor-initiating cells constitute a population within a tumor mass that shares properties with normal stem cells and is considered responsible for therapy failure in many cancers.
AMENDOLA, Donatella +20 more
core +6 more sources
Frontiers in Cell and Developmental Biology, 2021 A-type lamins are the main structural components of the nucleus, which are mainly localized at the nucleus periphery. First of all, A-type lamins, together with B-type lamins and proteins of the inner nuclear membrane, form a stiff structure—the nuclear ...
A. Malashicheva, K. Perepelina
semanticscholar +1 more source
Regulation of Lipid Metabolism by Lamin in Mutation-Related Diseases
Frontiers in Pharmacology, 2022 Nuclear lamins, known as type 5 intermediate fibers, are composed of lamin A, lamin C, lamin B1, and lamin B2, which are encoded by LMNA and LMNB genes, respectively.
Yue Peng +4 more
doaj +1 more source
PCAF Involvement in Lamin A/C-HDAC2 Interplay during the Early Phase of Muscle Differentiation
Cells, 2020 Lamin A/C has been implicated in the epigenetic regulation of muscle gene expression through dynamic interaction with chromatin domains and epigenetic enzymes. We previously showed that lamin A/C interacts with histone deacetylase 2 (HDAC2).
Spartaco Santi +4 more
doaj +1 more source
Fundamenta Mathematicae, 2022 Thurston introduced \emph{invariant (quadratic) laminations} in his 1984 preprint as a vehicle for understanding the connected Julia sets and the parameter space of quadratic polynomials. Important ingredients of his analysis of the angle doubling map $ _2$ on the unit circle $\mathbb{S}^1$ were the Central Strip Lemma, non-existence of wandering ...
Bhattacharya, Sourav +2 more
openaire +2 more sources
Cold Spring Harbor Perspectives in Biology, 2010 The nuclear lamins are type V intermediate filament proteins that are critically important for the structural properties of the nucleus. In addition, they are involved in the regulation of numerous nuclear processes, including DNA replication, transcription and chromatin organization.
Thomas, Dechat +4 more
openaire +2 more sources
Nucleic Acids Research, 2021 Telomere maintenance is essential to preserve genomic stability and involves telomere-specific proteins, DNA replication and repair proteins. Lamins are key components of the nuclear envelope and play numerous roles, including maintenance of the nuclear ...
Gaëlle Pennarun +11 more
semanticscholar +1 more source
Lamin A/C: Function in Normal and Tumor Cells
Cancers, 2020 Simple Summary The aim of this review is to summarize lamin A/C’s currently known functions in both normal and diseased cells. Lamin A/C is a nuclear protein with many functions in cells, such as maintaining a cell’s structural stability, cell motility ...
N. Dubik, S. Mai
semanticscholar +1 more source