Results 21 to 30 of about 52,713 (325)
Frontiers in Cell and Developmental Biology, 2021 A-type lamins are the main structural components of the nucleus, which are mainly localized at the nucleus periphery. First of all, A-type lamins, together with B-type lamins and proteins of the inner nuclear membrane, form a stiff structure—the nuclear ...
A. Malashicheva, K. Perepelina
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Lamin A, lamin B, and lamin B receptor analogues in yeast. [PDF]
The Journal of cell biology, 1989 Previous studies have shown that turkey erythrocyte lamin B is anchored to the nuclear envelope via a 58-kD integral membrane protein termed p58 or lamin B receptor (Worman H. J., J. Yuan, G. Blobel, and S. D. Georgatos. 1988. Proc. Natl. Acad. Sci. USA. 85:8531-8534). We now identify a p58 analogue in the yeast Saccharomyces cerevisiae.
Georgatos, S. D. +2 more
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Nucleic Acids Research, 2021 Telomere maintenance is essential to preserve genomic stability and involves telomere-specific proteins, DNA replication and repair proteins. Lamins are key components of the nuclear envelope and play numerous roles, including maintenance of the nuclear ...
Gaëlle Pennarun +11 more
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Lamin A and Prelamin a Counteract Migration of Osteosarcoma Cells
Cells, 2020 A type lamins are fundamental components of the nuclear lamina. Changes in lamin A expression correlate with malignant transformation in several cancers. However, the role of lamin A has not been explored in osteosarcoma (OS).
Camilla Evangelisti +11 more
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Regulation of Lipid Metabolism by Lamin in Mutation-Related Diseases
Frontiers in Pharmacology, 2022 Nuclear lamins, known as type 5 intermediate fibers, are composed of lamin A, lamin C, lamin B1, and lamin B2, which are encoded by LMNA and LMNB genes, respectively.
Yue Peng +4 more
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PCAF Involvement in Lamin A/C-HDAC2 Interplay during the Early Phase of Muscle Differentiation
Cells, 2020 Lamin A/C has been implicated in the epigenetic regulation of muscle gene expression through dynamic interaction with chromatin domains and epigenetic enzymes. We previously showed that lamin A/C interacts with histone deacetylase 2 (HDAC2).
Spartaco Santi +4 more
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Parameters optimization of heterojunction ZnSe/CdS/CIGS/Si solar cells using SCAPS-1D software
Revue des Énergies Renouvelables, 2022 It is required to simulate the performance of a photovoltaic solar cell performance to enhance it. Simulation optimization has the benefit of being inexpensive and straightforward, and it allows us to identify the optimum parameters that contribute to ...
Moussaab Belarbi +2 more
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The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence [PDF]
Open Biology, 2016 AKTIP is a shelterin-interacting protein required for replication of telomeric DNA. Here, we show that AKTIP biochemically interacts with A- and B-type lamins and affects lamin A, but not lamin C or B, expression.
Romina Burla +14 more
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Neddylation modification regulates lamin B1 expression in breast cancer [PDF]
Zhongguo aizheng zazhi, 2022 Background and purpose: The role of neddylation modification in breast cancer has rarely been reported. Previous study found that neddylation modification blocking induced cellular senescence in breast cancer, however, the potential mechanism has not yet
JIA Xiaoqing, SUN Xiaoyin, JIANG Beiqi, MEI Zhangyi, FU Yun, ZHUANG Zhigang
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Lamins and lamin-associated proteins
Current Opinion in Cell Biology, 1994 A variety of morphological and biochemical studies have established that the nuclear lamins play an important role in nuclear structure and dynamics. Recent work reveals the existence of specialized lamin isotypes and novel pathways of modulation of lamin import into the nucleus via phosphorylation by protein kinase C.
Georgatos, S. D., Meier, J., Simos, G.
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