Results 11 to 20 of about 82,088 (275)
The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence [PDF]
Open Biology, 2016 AKTIP is a shelterin-interacting protein required for replication of telomeric DNA. Here, we show that AKTIP biochemically interacts with A- and B-type lamins and affects lamin A, but not lamin C or B, expression.
Romina Burla +14 more
doaj +5 more sources
Current Biology, 2016 Xie and Burke discuss the roles of lamins in nuclear morphology and the pathological consequences of defects in these nuclear envelope proteins.
Wei, Xie, Brian, Burke
openaire +2 more sources
Regulation of Lipid Metabolism by Lamin in Mutation-Related Diseases
Frontiers in Pharmacology, 2022 Nuclear lamins, known as type 5 intermediate fibers, are composed of lamin A, lamin C, lamin B1, and lamin B2, which are encoded by LMNA and LMNB genes, respectively.
Yue Peng +4 more
doaj +1 more source
Fundamenta Mathematicae, 2022 Thurston introduced \emph{invariant (quadratic) laminations} in his 1984 preprint as a vehicle for understanding the connected Julia sets and the parameter space of quadratic polynomials. Important ingredients of his analysis of the angle doubling map $ _2$ on the unit circle $\mathbb{S}^1$ were the Central Strip Lemma, non-existence of wandering ...
Bhattacharya, Sourav +2 more
openaire +2 more sources
PCAF Involvement in Lamin A/C-HDAC2 Interplay during the Early Phase of Muscle Differentiation
Cells, 2020 Lamin A/C has been implicated in the epigenetic regulation of muscle gene expression through dynamic interaction with chromatin domains and epigenetic enzymes. We previously showed that lamin A/C interacts with histone deacetylase 2 (HDAC2).
Spartaco Santi +4 more
doaj +1 more source
Cold Spring Harbor Perspectives in Biology, 2010 The nuclear lamins are type V intermediate filament proteins that are critically important for the structural properties of the nucleus. In addition, they are involved in the regulation of numerous nuclear processes, including DNA replication, transcription and chromatin organization.
Thomas, Dechat +4 more
openaire +2 more sources
Down-regulation of the Lamin A/C in neuroblastoma triggers the expansion of tumor initiating cells [PDF]
, 2015 Tumor-initiating cells constitute a population within a tumor mass that shares properties with normal stem cells and is considered responsible for therapy failure in many cancers.
AMENDOLA, Donatella +20 more
core +2 more sources
Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes. [PDF]
, 2020 The nucleus of oocytes (germinal vesicle) is unusually large and its nuclear envelope (NE) is densely packed with nuclear pore complexes (NPCs) stockpiled for embryonic development. We showed that breakdown of this specialized NE is mediated by an Arp2/3-
Avilov, I. +6 more
core +1 more source
Lamins and lamin-associated proteins
Current Opinion in Cell Biology, 1994 A variety of morphological and biochemical studies have established that the nuclear lamins play an important role in nuclear structure and dynamics. Recent work reveals the existence of specialized lamin isotypes and novel pathways of modulation of lamin import into the nucleus via phosphorylation by protein kinase C.
Georgatos, S. D., Meier, J., Simos, G.
openaire +3 more sources
Promoter hypermethylation as a mechanism for Lamin A/C silencing in a subset of neuroblastoma cells. [PDF]
PLoS ONE, 2017 Nuclear lamins support the nuclear envelope and provide anchorage sites for chromatin. They are involved in DNA synthesis, transcription, and replication.
Ines Rauschert +7 more
doaj +1 more source