The role of lamin A and emerin in mediating genome organisation [PDF]
, 2010 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The nuclear matrix (NM) is proposed to be a permanent network of core filaments underlying thicker fibres, present regardless of transcriptional activity ...
Godwin, Lauren Sarah
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Parameters optimization of heterojunction ZnSe/CdS/CIGS/Si solar cells using SCAPS-1D software
Revue des Énergies Renouvelables, 2022 It is required to simulate the performance of a photovoltaic solar cell performance to enhance it. Simulation optimization has the benefit of being inexpensive and straightforward, and it allows us to identify the optimum parameters that contribute to ...
Moussaab Belarbi +2 more
doaj +1 more source
Space Jam-Ming: Generating Interstitial Space Using Fragmented Granular GelMA to Investigate Novel Paradigms of Cancer Metastasis. [PDF]
Adv Sci (Weinh)Microgels enable independent control of stiffness and interstitial space, overcoming limitations of conventional 3D hydrogels. Using fragmented gelatin methacryloyl microgels, we show that stiffness does not restrict non‐metastatic breast cancer growth, contrary to bulk hydrogels, and reveal the role of adherent‐to‐suspension transition in cancer ...
Vahala D +15 more
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Lamin A, lamin B, and lamin B receptor analogues in yeast. [PDF]
The Journal of cell biology, 1989 Previous studies have shown that turkey erythrocyte lamin B is anchored to the nuclear envelope via a 58-kD integral membrane protein termed p58 or lamin B receptor (Worman H. J., J. Yuan, G. Blobel, and S. D. Georgatos. 1988. Proc. Natl. Acad. Sci. USA. 85:8531-8534). We now identify a p58 analogue in the yeast Saccharomyces cerevisiae.
Georgatos, S. D. +2 more
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The Dynamics of Lamin a During the Cell Cycle
Frontiers in Molecular Biosciences, 2021 Lamin proteins play an essential role in maintaining the nuclear organization and integrity; and lamin A, in particular, plays a major role in the whole volume of the nuclear interior.
Anat Vivante +3 more
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Lamins and lamin-associated proteins
Current Opinion in Cell Biology, 1994 A variety of morphological and biochemical studies have established that the nuclear lamins play an important role in nuclear structure and dynamics. Recent work reveals the existence of specialized lamin isotypes and novel pathways of modulation of lamin import into the nucleus via phosphorylation by protein kinase C.
Georgatos, S. D., Meier, J., Simos, G.
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Involvement of the lamin rod domain in heterotypic lamin interactions important for nuclear organization [PDF]
, 2001 The nuclear lamina is a meshwork of intermediate-type filament proteins (lamins) that lines the inner nuclear membrane. The lamina is proposed to be an important determinant of nuclear structure, but there has been little direct testing of this idea.
Tinglu Guan +5 more
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Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression [PDF]
, 2007 Copyright @ 2007 The Rockefeller UniversityRadial organization of nuclei with peripheral gene-poor chromosomes and central gene-rich chromosomes is common and could depend on the nuclear boundary as a scaffold or position marker. To test this, we studied
Vaux, DJ +9 more
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Expression of chicken lamin B2 in Escherichia coli : characterization of its structure, assembly, and molecular interactions [PDF]
, 1991 Chicken lamin B2, a nuclear member of the intermediate-type filament (IF) protein family, was expressed as a full-length protein in Escherichia coli.
Aebi, U. +17 more
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Lamin-B protein marks the onset of physiological decline in young adult male Drosophila.
, 2022 (A-B) Western blot and quantification of the head lysates from different ages across male w1118 lifespan (blue, n = 180). Each biological replicate (diamond) has five heads.
Chin-Tong Ong (271233) +3 more
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