Results 81 to 90 of about 41,627 (225)
Cytoskeleton, EarlyView.ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves +3 more
wiley +1 more source
iScienceSummary: Lamins A and C are components of the lamina at the nuclear periphery and associate with heterochromatin. A distinct, relatively mobile pool of lamin A/C in the nuclear interior associates with euchromatic regions and with lamin-associated ...
Daria Filipczak +4 more
doaj +1 more source
Binding of lamin A to polynucleosomes
Journal of Biological Chemistry, 1991 Morphological observations suggest a close association between heterochromatin and the nuclear lamina. To investigate the molecular aspects of this association, we have established a simple sedimentation assay employing purified lamin proteins, or their 125I-labeled derivatives, and polynucleosomal particles isolated from avian erythrocytes.
Yuan, J. +3 more
openaire +3 more sources
Cytoskeleton, EarlyView.ABSTRACT Elastic tethers connect telomeres of separating chromosomes in anaphase of animal cells. Immunofluorescence staining of titin in crane‐fly spermatocytes, using 4 different antibodies, shows that the giant elastic protein titin seems to be a component of mitotic tethers: titin “strands” extend between separating chromosomes, connecting their ...
Demetra Economopoulos +5 more
wiley +1 more source
The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle
ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley +1 more source
Nature CommunicationsAlterations in nuclear structure and function are hallmarks of cancer cells. Little is known about these changes in Cancer-Associated Fibroblasts (CAFs), crucial components of the tumor microenvironment. Loss of the androgen receptor (AR) in human dermal
Soumitra Ghosh +8 more
doaj +1 more source
Lamin A/C and PI(4,5)P2—A Novel Complex in the Cell Nucleus
CellsLamins, the nuclear intermediate filaments, are important regulators of nuclear structural integrity as well as nuclear functional processes such as DNA transcription, replication and repair, and epigenetic regulations.
Sara Escudeiro-Lopes +3 more
doaj +1 more source
Micro Pattern‐Based 3D Cell Culture Platform: An Overview of Technologies and Applications
Exploration, EarlyView.Micro patterns are characterized as a coating of specific adhesion matrices on substrates to support cell growth. An overview of micropattern technology to regulate single cell morphology and fates, further focusing on the micro pattern‐based 3D cell culture platform used in the non‐tumor and tumor researches.
Xinglong Zhu +8 more
wiley +1 more source
Lamin A/C, laminopathies and premature ageing.
Histology and histopathology, 2008 Lamin A/C belongs to type V intermediate filaments and constitutes the nuclear lamina and nuclear matrix, where a variety of nuclear activities occur. Lamin A/C protein is firstly synthesized as a precursor and is further proteolytically processed by the zinc metallo-proteinase Ste24 (Zmpste24).
Zhou, Z, Liu, B
openaire +4 more sources
Journal of Experimental & Clinical Cancer Research, 2019 Background Macroautophagy (hereafter referred to as autophagy) is an evolutionarily conserved intracellular mechanism for lysosomal degradation of damaged cellular components.
Yunong Li +9 more
doaj +1 more source