Results 241 to 250 of about 1,866,196 (278)
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SUV39h‐ and A‐type lamin‐dependent telomere nuclear rearrangement
Journal of Cellular Biochemistry, 2010AbstractTelomeres are specialized chromatin structures that are situated at the end of linear chromosomes and play an important role in cell senescence and immortalization. Here, we investigated whether changes in histone signature influence the nuclear arrangement and positioning of telomeres.
Radka, Uhlírová +10 more
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A-type nuclear lamins, progerias and other degenerative disorders
Mechanisms of Ageing and Development, 2005Nuclear lamins were identified as core nuclear matrix constituents over 20 years ago. They have been ascribed structural roles such as maintaining nuclear integrity and assisting in nuclear envelope formation after mitosis, and have also been linked to nuclear activities including DNA replication and transcription. Recently, A-type lamin mutations have
Erica D, Smith +3 more
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A-type lamin-linked lipodystrophies.
Novartis Foundation symposium, 2005Lipodystrophies represent a group of diseases characterized by altered body fat repartition and major metabolic alterations with insulin resistance. Genetic forms of partial lipodystrophy are currently recognized as two syndromes with subcutaneous lipoatrophy but preserved or increased fat at the level of face and neck (Dunnigan syndrome or FPLD due to
Corinne, Vigouroux, Jacqueline, Capeau
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Identification of novel phosphorylation sites in murine A‐type lamins
European Journal of Biochemistry, 1993We report the distribution of phosphorylation sites in murine lamins A and C (A‐type lamins) in vitro and in vivo followed by reverse‐phase high‐performance liquid chromatography and micro‐sequencing of peptides spanning the almost complete lamin sequence. We show that two distinct protein kinases, cell‐division‐cycle‐2 kinase (cdc2 kinase) and protein
M, Eggert +5 more
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Chromosoma, 1990
Previous analyses of the nuclear lamina of mammalian cells have revealed three major protein components (lamins A, B and C) that have been identified by protein sequence homology as members of the intermediate filament (IF) protein family. It has been claimed that mammalian cells contain either all three lamins or lamin B alone.
T H, Höger +3 more
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Previous analyses of the nuclear lamina of mammalian cells have revealed three major protein components (lamins A, B and C) that have been identified by protein sequence homology as members of the intermediate filament (IF) protein family. It has been claimed that mammalian cells contain either all three lamins or lamin B alone.
T H, Höger +3 more
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Memory-type boundary control of a laminated Timoshenko beam
Mathematics and Mechanics of Solids, 2020In this paper, we consider a laminated Timoshenko beam with boundary conditions of a memory type. This structure is given by two identical uniform layers, one on top of the other, taking into account that an adhesive of small thickness bonds the two surfaces and produces an interfacial slip.
Baowei Feng, Abdelaziz Soufyane
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[Research progress in A-type lamins].
Sheng li ke xue jin zhan [Progress in physiology], 2012A-type lamins are encoded by LMNA and a major component of the nuclear lamina, a dynamic meshwork located just under the nuclear envelope, providing essential mechanical support. In addition, A-type lamins associate with chromatin both directly and indirectly and have been suggested to play important roles in chromatin organization, transcription, DNA ...
Chun-Hai, Gao +2 more
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Chromosoma, 1992
Nuclear lamins are intermediate filament (IF) type proteins that form a fibrillar network underlying the inner nuclear membrane. The existence of multiple subtypes of lamins in vertebrates has been interpreted in terms of functional specialization during cell division and differentiation.
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Nuclear lamins are intermediate filament (IF) type proteins that form a fibrillar network underlying the inner nuclear membrane. The existence of multiple subtypes of lamins in vertebrates has been interpreted in terms of functional specialization during cell division and differentiation.
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A-type lamin dynamics in bovine somatic cell nuclear transfer embryos
Reproduction, Fertility and Development, 2010The persistence of A-type nuclear lamin in somatic cell nuclear transfer (SCNT) embryos has been proposed as a marker for incomplete nuclear reprogramming. Using monoclonal antibodies to A/C- (A/C-346 and A/C-131C3) and B-type lamin, we compared distribution during early development of bovine IVF, parthenogenetic and SCNT embryos.
Richard D W, Kelly +2 more
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Journal of Cell Science, 1991
ABSTRACT The nuclear lamina is an intermediate filament-type network underlying the inner nuclear membrane. It is believed to be important for nuclear envelope integrity and the organization of interphase chromatin. On the basis of biochemical properties and sequence criteria, vertebrate lamin proteins are classified as either A- or B ...
Peter, M., Nigg, E. A.
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ABSTRACT The nuclear lamina is an intermediate filament-type network underlying the inner nuclear membrane. It is believed to be important for nuclear envelope integrity and the organization of interphase chromatin. On the basis of biochemical properties and sequence criteria, vertebrate lamin proteins are classified as either A- or B ...
Peter, M., Nigg, E. A.
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