Results 101 to 110 of about 10,232,392 (268)

Guanosine‐Quadruplex Hydrogels as Dynamic, Mechanically Tunable and Ion Conductive 3D Scaffolds for Cell Culture Applications

open access: yesAdvanced Functional Materials, EarlyView.
Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur   +10 more
wiley   +1 more source

Ultra‐Thin Tow‐Based Discontinuous Composites—Material Overview and Aspirations

open access: yesAdvanced Functional Materials, EarlyView.
Tow‐based discontinuous composites made from ultra‐thin tapes offer outstanding in‐plane mechanical properties. This material, inspired by Nacre, has high volume fraction of tapes exceeding 90 % and allows for quasi‐isotropic material plates less than 100 micrometer in thickness.
Ioannis Katsivalis   +8 more
wiley   +1 more source

Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford Progeria Syndrome

open access: yes, 2019
Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder characterized by the onset of some age-related phenotypes including arthritis, lipodystrophy and atherosclerosis at a very early age. Cells from HGPS patients express a mutant version of the nuclear envelope component Lamin A (termed Progerin) and have previously been reported to ...
openaire   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar   +6 more
wiley   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez   +12 more
wiley   +1 more source

A sub-set of guanine- and cytosine-rich genes are actively transcribed at the nuclear lamin B1 region

open access: yesCellular and Molecular Life Sciences
Chromatin organization in the mammalian cell nucleus plays a vital role in the regulation of gene expression. The lamina-associated domain at the inner nuclear membrane has been shown to harbor heterochromatin, while the nuclear interior has been shown ...
Gayan I. Balasooriya   +3 more
doaj   +1 more source

Overexpression of the heterochromatinization factor BAHD1 in HEK293 cells differentially reshapes the DNA methylome on autosomes and X chromosome.

open access: yesFrontiers in Genetics, 2015
BAH domain-containing protein 1 (BAHD1) is involved in heterochromatin formation and gene repression in human cells. BAHD1 also localizes to the inactive X chromosome (Xi), but the functional significance of this targeting is unknown. So far, research on
Emanuele eLibertini   +21 more
doaj   +1 more source

LAMINA: a tool for rapid quantification of leaf size and shape parameters-0

open access: yes, 2011
Comparison of leaf area data generated using ImageJ and LAMINA.Copyright information:Taken from "LAMINA: a tool for rapid quantification of leaf size and shape parameters"http://www.biomedcentral.com/1471-2229/8/82BMC Plant Biology 2008;8():82-82 ...
Petter Gustafsson (3296)   +7 more
core   +1 more source

Modeling Early Metastatic Progression in Breast Cancer Using a Barrier‐Free, Perfusable Spheroid‐on‐a‐Chip Platform

open access: yesAdvanced Healthcare Materials, EarlyView.
Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko   +7 more
wiley   +1 more source

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