Results 141 to 150 of about 53,308 (249)

Architecture and regulation of nanoscale chromatin domains. [PDF]

Nat Commun
Vinayak V, Lakadamyali M, Shenoy VB.
europepmc   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

Advanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du, Yinming Li, Ziyue Li, Yuedan Wang, Shaopeng Li, Yijie Wang, Yingying Qu, Bingyang Lv, Ying Li, Ting Chen, Yu Zhou, Xuan Xiao   +11 more
wiley   +1 more source

Histologic signatures as predictors of intestinal barrier impairment in inflammatory bowel disease: integration with endoscopic and molecular markers. [PDF]

J Crohns Colitis
Lo Bello A, Zammarchi I, Pugliano CL, Majumder S, Hughes R, Crotty R, Hayes B, Burke L, Ghosh S, Iacucci M.   +9 more
europepmc   +1 more source

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

Advanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo, Yuanyuan Meng, Qixiang Gui, Xi‐Tao Yang, Yong Fan, Xiaodong Zhu   +5 more
wiley   +1 more source

Gravity as a Boundary Condition for the Evolution of Three-Dimensional Multicellularity. [PDF]

Life (Basel)
Ullrich O, Thiel CS.
europepmc   +1 more source

An Edible Biohybrid Platform Accomplishes In Situ Fenton‐Mediated Enteral Nanoplastics Aging and Excretion

Advanced Science, EarlyView.
An edible biohybrid platform triggers nanoplastics (NPs) aging and agglomeration by in situ generating hydroxyl radicals within the intestine. The enlarged NPs are unable to penetrate the intestine and are subsequently excreted. Simultaneously, probiotic biofilms reinforce the intestinal barrier.
Su Zhou, Anran Yan, Haowei Guo, Ping Chen, Qiang Chu   +4 more
wiley   +1 more source

Exploration of the signaling pathway involving OsCSN8 in regulating the leaf angle of rice. [PDF]

Theor Appl Genet
Yu X, Wang Z, Li C, Zhang C, Liu Y, Zhang C, Xu M, Wu M, Guo L.   +8 more
europepmc   +1 more source

Accurately Deciphering Tissue Heterogeneity From Spatial Multi‐Modal and Multi‐Omics With STransformer

Advanced Science, EarlyView.
STransformer is a unified deep learning framework designed to seamlessly accommodate a comprehensive landscape of spatial data. By simultaneously capturing short‐range cellular interactions and tissue‐wide semantic patterns, it extracts robust representations to accurately dissect complex tissue heterogeneity.
Xingyi Li, Jialuo Xu, Gaoyuan Du, Xiangting Jia, Dongmin Zhao, Chunyan Zhou, Kexin Xiao, Jia Gu, Junnan Zhu, Xuequn Shang   +9 more
wiley   +1 more source

Lamin A/C as a Molecular Link Between Nuclear Organization, Chromatin Dynamics, and Tumor Progression. [PDF]

Cells
Foglini C, Scotlandi K, Pasello M.
europepmc   +1 more source

Pressure‐Induced Drift Artifacts in Stretchable Liquid Metal ThinFilm Electrocardiogram Electrodes

Advanced Science, EarlyView.
A stretchable LM electrode integrated with a strain sensor enables in situ quantitative investigation of drift artifact and skin deformation. This reveals the significance of pressure‐induced drift artifact and its intimate relationship with the skin potential model.
Ding Li, Zi‐Gan Xu, Zhi‐Kang Chen, Shuo‐Yan Xu, Jia‐Yi Cui, Si‐Yuan Wo, Zi‐Xu Wang, Yi‐Kun Liu, Jia‐Ju Yin, Hou‐Fang Liu, Xiao‐Ming Wu, Lu‐Qi Tao, Yi Yang, Tian‐Ling Ren   +13 more
wiley   +1 more source