Results 211 to 220 of about 53,308 (249)

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

Immune discrimination between commensals and pathogenic bacteria. [PDF]

Virulence
Alanazi HH.
europepmc   +1 more source

Single‐Sensor Vibration Sensing in Anisotropic Composites Enabled by Disordered Metasurfaces

Advanced Science, EarlyView.
This work develops a single‐sensor vibration sensing (SSVS) framework that integrates disordered metasurfaces with compressive sensing. Comprehensive numerical and experimental validations demonstrate that, by manipulating anisotropic guided wave propagation through metasurfaces, the proposed SSVS framework enables high‐fidelity multi‐source vibration ...
Jianjie Zhang, Lanhe Xu, Zhongzheng Zhang, Yongbo Li, Eric Li, Asoke K. Nandi, Bing Li   +6 more
wiley   +1 more source

Faculty Opinions recommendation of A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2018
openaire   +2 more sources

Block-and-Lock Approaches for HIV Cure: Mechanistic Insights, Challenges, and Emerging Role of CPSF6. [PDF]

Int J Mol Sci
Tolomeo M, Cascio A.
europepmc   +1 more source

Dynamic changes in Lamin B1 and heterochromatin coincide with chromatin condensation during human erythropoiesis. [PDF]

Genome Biol
Wen R, Zhang Q, Li Y, Chen Y, Jiang Y, Lu Y, Zhu J, Kong D, Xu Y, Liu X, Qian P, Zhang M, Huang H, Huo D.   +13 more
europepmc   +1 more source

Research progress on pathogenic genes of dilated cardiomyopathy. [PDF]

iScience
Zhang X, Zhang X, Chen Y, Huan N, Wang C, Zhang D.   +5 more
europepmc   +1 more source

Current Topics of Progressive Cardiac Conduction Disease. [PDF]

J Arrhythm
Sumitomo N, Mori H, Kumamoto T, Ishikawa T, Seki A, Makita N, Schott JJ, Wilde AAM.   +7 more
europepmc   +1 more source

Mechanical-biochemical signaling accelerates scleral remodeling in myopia via the LaminA/C-Emerin-MKL1 axis. [PDF]

Cell Commun Signal
Liu Y, Liu X, Liu M, Wang X, Qian W, Zhao T, Li M, Ke B.   +7 more
europepmc   +1 more source

C3 molecular structural and histopathological analyses in a pediatric case of atypical hemolytic uremic syndrome with life-threatening gastrointestinal bleeding-a case report. [PDF]

Front Pediatr
Enya T, Miyazaki K, Kuge S, Morimoto Y, Kondou H, Sakata N, Joh K, Nagano C, Nozu K, Ito N, Hakata Y, Sugimoto K, Miyazawa M.   +12 more
europepmc   +1 more source