Results 71 to 80 of about 18,858 (196)
Efficacy of Lamotrigin in Treatment of Avoidance / Numbing in Post-traumatic Stress Disorders
: Introduction & Objective: Post-traumatic stress disorder (PTSD) is a chronic illness which is difficult to treat yet, it is a common disorder which is associated with significant morbidity and mortality. The hypothesis that exposure to traumatic events
S Amanat, H Afshar
doaj
Abstract Objective Early response to anti‐seizure medication (ASM) is associated with a favorable prognosis in patients with epilepsy. Research is required to confirm existing data on the clinical use of perampanel as first adjunctive therapy in different patient groups and different regions.
Stefano Meletti +10 more
wiley +1 more source
Older individuals may be more susceptible to cognitive side effects of antiepileptic drugs than are younger adults. This randomized, double-blind study compared the cognitive effects of lamotrigine (median maintenance dosage, 500.0 mg/d) and topiramate ...
Steve S. Chung +3 more
doaj +1 more source
Cardiovascular morbidity following epilepsy: A nationwide retrospective cohort study in South Korea
Abstract Objective This study evaluated the long‐term risk of major cardiovascular diseases (CVDs) in patients with epilepsy using a nationwide cohort, aiming to address critical gaps in population‐based evidence on brain–heart interactions. Methods Data from the Korean National Health Insurance Service (2002–2013) were analyzed.
Youngoh Bae +5 more
wiley +1 more source
Abstract Objective Artificial intelligence (AI)‐powered chatbots are increasingly used for patient education and mental health support, yet their effectiveness in epilepsy care remains underexplored. This study examines text‐based interactions between users and EpiloBot, an epilepsy‐focused chatbot, to understand conversational patterns and emotional ...
Keiichi Watanuki +10 more
wiley +1 more source
Stiripentol use in Dravet syndrome patients in the USA: Results of a real‐world study
Abstract Objective Dravet syndrome (DS) is a severe developmental and epileptic encephalopathy with a high seizure burden and mortality risk. Stiripentol, one of the first DS‐specific therapies, received FDA approval in 2018 but its real‐world use and impact post‐approval in the USA remain insufficiently characterized.
Elaine Wirrell +11 more
wiley +1 more source
The treatment recommendations in obsessive-compulsive disorder (OCD) after lack of response to selective serotonin reuptake inhibitors (SSRIs) include augmentation with other drugs, particularly clomipramine, a more potent serotonin reuptake inhibitor ...
Manuel Arrojo-Romero +2 more
doaj +1 more source
Ultra‐refractory epilepsy: The newly described entity
Abstract Objective Drug‐resistant epilepsy (DRE) is defined as the failure of two antiseizure medications (ASMs) to achieve complete seizure control, affecting approximately 30% of epilepsy patients. In some cases, additional ASMs and surgical approaches are also unsuccessful.
Jan Vinklárek +13 more
wiley +1 more source
Highly purified cannabidiol (CBD) in CDKL5 deficiency disorder (CDD): Open‐label prospective study
Abstract Objective CDKL5 deficiency disorder (CDD) is an early‐onset developmental and epileptic encephalopathy characterized by frequent drug‐resistant seizures, cerebral visual impairment, motor dysfunction, and sleep and gastrointestinal disturbances.
Marco Perulli +12 more
wiley +1 more source

