Results 131 to 140 of about 149,549 (315)
Modelling cell-cell collision and adhesion with the Filament Based Lamellipodium Model [PDF]
We extend the live-cell motility Filament Based Lamellipodium Model to incorporate the forces exerted on the lamellipodium of the cells due to cell-cell collision and cadherin induced cell-cell adhesion. We take into account the nature of these forces via physical and biological constraints and modelling assumptions. We investigate the effect these new
arxiv
Introduction A case of Langerhans cell histiocytosis (LGH) involving extensive area of base of skull resulting in panhypopituitarism and diabetes insipidus (DI) is reported.
Anirban Ghosh+2 more
doaj +1 more source
Abstract Aims The NHS Diabetes Prevention Programme (DPP) is a behaviour‐change programme aimed at adults diagnosed with non‐diabetic hyperglycaemia (NDH), who are at higher risk of developing type 2 diabetes mellitus (Diabetes). This paper explores the heterogeneity in the effectiveness of the DPP by age, sex, BMI, and practice location deprivation ...
Rathi Ravindrarajah+3 more
wiley +1 more source
Resting respiratory tract dendritic cells preferentially stimulate T helper cell Type 2(Th2) responses and require obligatory cytokine signals for induction of Th1 immunity [PDF]
Consistent with their role in host defense, mature dendritic cells (DCs) from central lymphoid organs preferentially prime for T helper cell type 1 (Th1)-polarized immunity.
Holt, P.G.+6 more
core +2 more sources
The clinical manifestations of Langerhans cell histiocytosis have been recognized for more than a century. For most of that time, physicians have viewed the disease from different perspectives, interpreting portions of its clinical spectrum as if they were distinct and unrelated entities.
Department of Ophthalmology and Pathology, University of South Florida, College of Medicine, and Section of Ophthalmology James A. Haley Veterans Hospital, Tampa, Florida, USA ( host institution )+2 more
openaire +4 more sources
Abstract Type 1 diabetes is recognized as a chronic disease with a presymptomatic phase that does not require insulin therapy and a clinical phase where insulin treatment becomes necessary. The presymptomatic phase is characterized by the presence of autoantibodies targeting pancreatic islet beta cell antigens (islet autoantibodies).
Ezio Bonifacio+1 more
wiley +1 more source
The cell cycle related rhythms, cells' states correlation and the cancer [PDF]
We consider the decision making by mammalian cells, looking them as dynamic systems with rhythms. We calculate the effective dimension of the cell division model of the healthy mammalian cells consistent with the data: it is described via a four dimensional dynamic system. We assume that the cell's decision making property is strongly affected by the
arxiv
Computational Approach to Identifying Universal Macrophage Biomarkers. [PDF]
Macrophages engulf and digest microbes, cellular debris, and various disease-associated cells throughout the body. Understanding the dynamics of macrophage gene expression is crucial for studying human diseases. As both bulk RNAseq and single cell RNAseq
Dang, Dharanidhar+5 more
core +1 more source
SERIAL RECONSTRUCTION OF THE CHARACTERISTIC GRANULE OF THE LANGERHANS CELL [PDF]
Richard W. Sagebiel, Thomas H. Reed
openalex +1 more source
Macrophages and autophagy: partners in crime
Autophagy is a key regulator of macrophage function, influencing critical processes like polarization, cytokine secretion, and phagocytosis. Its impact on macrophage behavior varies across different tissues and disease contexts, where it can either promote protective responses or contribute to detrimental outcomes, depending on the physiological or ...
Alessandra Vitaliti+2 more
wiley +1 more source