Results 131 to 140 of about 110,625 (292)

Hair follicle stem cell fate supports distinct clinical endotypes in hidradenitis suppurativa

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Hair follicles (HFs) were extracted from skin biopsies. From these, original sequencing data were obtained and integrated with two independent studies to build a HF single‐cell transcriptomic atlas. It enabled delineating the fate of HF stem cells.
Audrey Onfroy, Francette Jean‐Louis, Philippe Le Corvoisier, Fanny Coulpier, Kévin Muret, Eric Bonnet, Raphaele Arrouasse, Caroline Boucle, Salwa Abid, Emilie Sbidian, Christina Bergqvist, Pierre Wolkenstein, Véronique Godot, Jean‐François Deleuze, Yves Lévy, Piotr Topilko, Etienne Audureau, Sophie Hue   +17 more
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Paediatric Langerhans cell histiocytosis with diabetes insipidus: remarkable recovery journey

Journal of the Pakistan Medical Association
A rare condition known as Langerhans cell histiocytosis (LCH) is characterised by the clonal growth of dendritic cells called Langerhans cells, which play a significant role in the immune system. A diverse range of clinical presentations are probable as
Versha Rani Rai, Zulqarnain Buriro, Roshia Parveen, Mohsina Noor, Heeranand Rathore   +4 more
doaj   +1 more source

Engineering Marker‐Free Lettuce Chloroplast Genome to Express Functional Glucagon‐Like Peptide‐1 Receptor Agonists Exenatide and Lixisenatide

Plant Biotechnology Journal, EarlyView.
Engineering of marker‐free lettuce chloroplast genome to express CTB‐Exenatide and CTB‐Lixisenatide for oral delivery. Upper panel: Chemically synthesised exenatide or lixisenatide require expensive production, purification, refrigeration and invasive delivery methods.
Rahul Singh, Henry Daniell
wiley   +1 more source

Early antitumor activity of oral Langerhans cells is compromised by a carcinogen

, 2022
Yasmin Saba, Itay Aizenbud, Daniela Matanes, Noam Koren, Or Barel, Khalid Zubeidat, Tal Capucha, Eyal David, Luba Eli‐Berchoer, Patrizia Stoitzner, Asaf Wilensky, Ido Amit, Rakefet Czerninski, Simon Yona, Avi‐Hai Hovav   +14 more
openalex   +1 more source

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

Photochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal, Durdana Muntaqua, Gagan Chhabra, Nihal Ahmad   +3 more
wiley   +1 more source

Partial Regeneration/Proliferation of the .BETA.-Cells in the Islets of Langerhans by Nigella sativa L. in Streptozotocin-Induced Diabetic Rats

, 2003
Mehmet Kanter, İsmail Meral, Zabit Yener, Hanefi Özbek, Halit Demir   +4 more
openalex   +2 more sources

Congenital Adrenal Hyperplasia: A Case Report with Premature Teeth Exfoliation and Bone Resorption [PDF]

, 2015
Congenital adrenal hyperplasia (CAH) is an inherited autosomal recessive disorder characterized by insufficient production of cortisol. The aim of this case report was to present a child with CAH, premature exfoliation of primary teeth and accelerated ...
Angelopoulou, Matina V., Emmanouil, Dimitris E., Kontogiorgos, Elias D.   +2 more
core   +1 more source

Immunomodulatory effects of photodynamic therapy for skin cancer: Potential strategies to improve treatment efficacy and tolerability

Photochemistry and Photobiology, EarlyView.
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio, Sanjay Anand, Jeffrey B. Travers, Edward V. Maytin, Craig A. Rohan   +4 more
wiley   +1 more source