Results 51 to 60 of about 149,549 (315)

A cell membrane model that reproduces cortical flow-driven cell migration and collective movement [PDF]

open access: yes, 2023
Many fundamental biological processes are dependent on cellular migration. Although the mechanical mechanisms of single-cell migration are relatively well understood, those underlying migration of multiple cells adhered to each other in a cluster, referred to as cluster migration, are poorly understood.
arxiv   +1 more source

Common clonal origin of an acute B-lymphoblastic leukemia and a Langerhans’ cell sarcoma: evidence for hematopoietic plasticity

open access: yesHaematologica, 2010
Background The hierarchical organization of hematopoiesis with unidirectional lineage determination has become a questionable tenet in view of the experimental evidence of reprogramming and transdifferentiation of lineage-determined cells.
Richard Ratei   +10 more
doaj   +1 more source

Langerhans cell histiocytosis

open access: yesКлинический разбор в общей медицине, 2023
Langerhans cell histiocytosis is a rare proliferative disease of histiocyte-like cells, the peak incidence of which occurs in early childhood. Pulmonary Langerhans Cell Histiocytosis is one of the forms of this disease, but it usually affects young ...
Victor V. Fomin   +4 more
doaj   +1 more source

Quantitation of Cutaneous Langerhans Cells of Sarcoidosis Patients [PDF]

open access: yes, 1983
Langerhans cells play a role in cell-mediated immune reactions which are often depressed in sarcoidosis. We examined the epidermis of 17 anergic patients with sarcoidosis (Kveim-reactive and/or biopsy-proved) for the number of Langerhans cells in ...
Berman, Brian   +4 more
core   +1 more source

The Origin of Langerhans Cells

open access: yesJournal of Investigative Dermatology, 1980
Langerhans cells constitute a morphologically well-characterized subpopulation (3--8%) of mammalian epidermal cells and, in contrast to the bulk of epidermal cells, bear Fc-IgG and C3 receptors, express immune response associated (Ia) antigens, and function as antigen presenting cells and allogeneic stimulatory cells to primed T lymphocytes.
Kunihiko Tamaki   +2 more
openaire   +3 more sources

A Local Counter-Regulatory Motif Modulates the Global Phase of Hormonal Oscillations [PDF]

open access: yes, 2016
Counter-regulatory elements maintain dynamic equilibrium ubiquitously in living systems. The most prominent example, which is critical to mammalian survival, is that of pancreatic {\alpha} and {\beta} cells producing glucagon and insulin for glucose homeostasis.
arxiv   +1 more source

Langerhans cell histiocytosis of the maxillae in a child treated only with chemotherapy: a case report

open access: yesJournal of Medical Case Reports, 2017
Background Langerhans cell histiocytosis is a sporadic disease caused by an uncontrolled pathogenic clonal proliferation of dendritic cells that have Langerhans cell characteristics.
Angela Pia Cazzolla   +9 more
doaj   +1 more source

Mafb lineage tracing to distinguish macrophages from other immune lineages reveals dual identity of Langerhans cells [PDF]

open access: yes, 2016
Current systems for conditional gene deletion within mouse macrophage lineages are limited by ectopic activity or low efficiency. In this study, we generated a Mafb-driven Cre strain to determine whether any dendritic cells (DCs) identified by Zbtb46-GFP
Abram   +78 more
core   +2 more sources

Evaluation of serum miR‐216a and miR‐375 as biomarkers in dogs with acute pancreatitis

open access: yesJournal of Veterinary Internal Medicine, Volume 37, Issue 1, Page 92-100, January/February 2023., 2023
Abstract Background Serum microRNAs have emerged as biomarkers of various diseases. Overexpression of serum miR‐216a and miR‐375 occurs in dogs with experimentally induced acute pancreatitis (AP). Objectives To identify the possibility of using serum miR‐216a and miR‐375 as biomarkers for the diagnosis and evaluation of treatment response in dogs with ...
Dohee Lee   +7 more
wiley   +1 more source

Physical Confinement and Cell Proximity Increase Cell Migration Rates and Invasiveness: A Mathematical Model of Cancer Cell Invasion through Flexible Channels [PDF]

open access: yes, 2022
Cancer cell migration between different body parts is the driving force behind cancer metastasis, which is the main cause of mortality of patients. Migration of cancer cells often proceeds by penetration through narrow cavities in locally stiff, yet flexible tissues. In our previous work, we developed a model for cell geometry evolution during invasion,
arxiv   +1 more source

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