Results 31 to 40 of about 39,048 (228)
Entrapment of Cultured Pancreas Islets in Three-Dimensional Collagen Matrices
In vitro culture of islets of Langerhans decreases their immunogenecity, presumably by eliminating passenger leukocytes and other Ia+ presenting cells within the islets.
Seh-Huang Chao +3 more
doaj +1 more source
The creation of a cell-engineered pancreatic construct (CEPC) from islets of Langerhans and biocompatible matrix carrier (framework/scaffold), which imitates the native microenvironment of pancreatic tissue, is an approach to the treatment of type I ...
N. V. Baranova +6 more
doaj +1 more source
The effect of ghrelin on Kiss-1 and KissR gene transcription and insulin secretion in rat islets of Langerhans and CRI-D2 cell line [PDF]
Objective(s): Ghrelin is a peptide hormone that has been shown to have numerous central and peripheral effects. The central effects including GH secretion, food intake, and energy homeostasis are partly mediated by Kiss1- KissR signaling pathway. Ghrelin
Mandana Mahmoodzaeh Sagheb +2 more
doaj +1 more source
The types of endocrine cells in the pancreas of Sunda porcupine (Hystrix javanica) [PDF]
Aim: To identify the types of endocrine cells in the pancreas of the Sunda porcupine (Hystrix javanica) and its immunolocalization. Materials and Methods: Five adult H. javanica were used without sexual distinction.
Teguh Budipitojo +2 more
doaj +1 more source
Cyclic AMP signalling in pancreatic islets [PDF]
Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Furman, Brian +2 more
core +1 more source
Size Distribution of Mouse Langerhans Islets [PDF]
Pancreatic beta-cells are clustered in islets of Langerhans, which are typically a few hundred micrometers in a variety of mammals. In this study, we propose a theoretical model for the growth of pancreatic islets and derive the islet size distribution, based on two recent observations: First, the neogenesis of new islets becomes negligible after some ...
Jo, Junghyo +2 more
openaire +2 more sources
Potential of [11C]UCB-J as a PET tracer for islets of Langerhans
Biomarkers for the measurement of islets of Langerhans could help elucidate the etiology of diabetes. Synaptic vesicle glycoprotein 2 A (SV2A) is a potential marker reported to be localized in the endocrine pancreas.
Emmi Puuvuori +5 more
doaj +1 more source
Pancreatic islet transplantation after upper abdominal exeriteration and liver replacement [PDF]
Nine patients who became diabetic after upper-abdominal exenteration and liver transplantation were given pancreatic islet-cell grafts obtained from the liver donor (eight cases), a third-party donor (one), or both (four). Two patients were diabetic when
Alejandro, R +8 more
core +1 more source
Negative Feedback Synchronizes Islets of Langerhans [PDF]
Insulin is released from the pancreas in pulses with a period of ~ 5 min. These oscillatory insulin levels are essential for proper liver utilization and perturbed pulsatility is observed in type 2 diabetes. What coordinates the many islets of Langerhans throughout the pancreas to produce unified oscillations of insulin secretion?
Dhumpa, Raghuram +4 more
openaire +2 more sources
Introduction: Calorie consumption that exceeds normal limits each year can be a risk factor in causing diabetes mellitus (DM). This condition causes the body to be in a state of hyperglycemia, which will trigger changes in the diameter and number of ...
Eny Wulan Sari +3 more
doaj +1 more source

