Results 101 to 110 of about 8,574 (229)

Langerin+ DCs regulate innate IL-17 production in the oral mucosa during Candida albicans-mediated infection.

PLoS Pathogens, 2018
The opportunistic fungal pathogen Candida albicans frequently causes diseases such as oropharyngeal candidiasis (OPC) in immunocompromised individuals. Although it is well appreciated that the cytokine IL-17 is crucial for protective immunity against OPC,
Florian Sparber, Tamas Dolowschiak, Sarah Mertens, Laura Lauener, Björn E Clausen, Nicole Joller, Patrizia Stoitzner, Roxane Tussiwand, Salomé LeibundGut-Landmann   +8 more
doaj   +1 more source

Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract [PDF]

, 2013
Developing efficacious vaccines against enteric diseases is a global challenge that requires a better understanding of cellular recruitment dynamics at the mucosal surfaces.
Brane, Lucas, Cheong, Cheolho, Choi, Jae-Hoon, Do, Yoonkyung, Lavelle, Ed C., Mayer, Lloyd, Mehandru, Saurabh, Mucida, Daniel, Poles, Jordan, Reis, Bernardo Sgarbi, Ruane, Darren, Steinman, Ralph M., Studt, Natalie, Velinzon, Klara, Zhu, Hongfa   +14 more
core   +2 more sources

Usutu virus escapes langerin-induced restriction to productively infect human Langerhans cells, unlike West Nile virus [PDF]

, 2021
Marie Martin, Ghizlane Maarifi, Hervé Abiven, Marine Seffals, Nicolas Mouchet, Cécile Beck, Charles Bodet, Nicolas Lévêque, Nathalie J. Arhel, Fabien P. Blanchet, Yannick Simonin, Sébastien Nisole   +11 more
openalex   +1 more source

Tissue‐Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts

American Journal of Hematology, Volume 100, Issue 12, Page 2305-2319, December 2025.
ABSTRACT Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age, sex, and genetic and epigenetic signatures.
Peter Valent, Johann Wojta, Petri T. Kovanen, Olivier Hermine, Falko Fend, Karl Sotlar, Hildegard Greinix, Klaus Geissler, Karin Hartmann, Juliana Schwaab, Marco Herling, Laura Boccuni, Lukas Kazianka, Max Vincent John, Wolfgang R. Sperr, Carina Zierfuss, Alexandar Tzankov, Christian Sillaber, Milen Minkov, Gregor Hoermann, Matthew Collin, Hans‐Peter Horny, Torsten Haferlach, Maria Sibilia, Julien Haroche, Paul La Rosée, Alberto Orfao, Michel Arock   +27 more
wiley   +1 more source

Exploiting the role of endogenous lymphoid-resident dendritic cells in the priming of NKT cells and CD8+ T cells to dendritic cell-based vaccines.

PLoS ONE, 2011
Transfer of antigen between antigen-presenting cells (APCs) is potentially a physiologically relevant mechanism to spread antigen to cells with specialized stimulatory functions.
Troels R Petersen, Dianne Sika-Paotonu, Deborah A Knight, Helen M A Simkins, Ian F Hermans   +4 more
doaj   +1 more source

Duality of β-glucan microparticles: antigen carrier and immunostimulants [PDF]

, 2016
Designing efficient recombinant mucosal vaccines against enteric diseases is still a major challenge. Mucosal delivery of recombinant vaccines requires encapsulation in potent immunostimulatory particles to induce an efficient immune response. This paper
Baert, Kim, Cox, Eric, De Geest, Bruno, De Greve, Henri, Devriendt, Bert   +4 more
core   +2 more sources

Tumoral Stage of Mycosis Fungoides, Misdiagnosed With Wells Syndrome and Langerhans Cell Histiocytosis Histologically: A Challenging Case and Review of the Literature

Cancer Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background Mycosis fungoides (MF) is a type of cutaneous T‐cell lymphoma (CTCL) with slow progression, usually presenting with patches and plaques. The infiltration of histiocytes and eosinophils in skin cancers can mask the underlying condition, posing a diagnostic challenge.
Seyed Mohammad Vahabi, Sahar Montazeri, Elnaz Pourgholi, Saeed Bahramian, Alireza Ghanadan, Kambiz Kamyab Hesari, Ifa Etesami   +6 more
wiley   +1 more source

Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model

Barrier Immunity, Volume 1, Issue 1, Page 27-44, December 2025.
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia, Mathias Hochgerner, Qingzhen Wei, Xian'ge Zhong, Jiucun Wang   +4 more
wiley   +1 more source

The Role of Langerin⁺ CD8α⁺ Dendritic Cells in Tumour Immunotherapy [PDF]

, 2021
<p>The immune system has the potential to selectively target and eliminate tumours cells. However, the induction of an immunosuppressive environment by factors released by tumours cells, or by the tumour stroma, in combination with difficulties in differentiating between healthy and malignant cells, contributes to inefficient or disabled anti ...
openaire   +1 more source

Systematic Chemoenzymatic Synthesis of O-Sulfated Sialyl Lewis x Antigens. [PDF]

, 2015
O-Sulfated sialyl Lewis x antigens play important roles in nature. However, due to their structural complexity, they are not readily accessible by either chemical or enzymatic synthetic processes.
Chen, Xi, Kenyond, Nicholas J, Li, Yanhong, Louie, Angelique Y, Muthana, Musleh M, Santra, Abhishek, Tasnima, Nova, Yu, Hai, Zeng, Jie   +8 more
core   +1 more source