Results 41 to 50 of about 17,586 (206)

Exploring hidden dimensions of soil fungal biodiversity: A simple technique to detect soil fungi resistant to antifungal compounds [PDF]

open access: yes, 2010
Soils are known to be ultimate and complex reservoirs of microbial diversity. The complex dimensions of bacterial and fungal diversity in tropical soils and microbial community dynamics are underexplored.
Nandkumar M. Kamat   +1 more
core   +2 more sources

Lanosterol Synthase Pathway Alleviates Lens Opacity in Age-Related Cortical Cataract

open access: yesJournal of Ophthalmology, 2018
Purpose. Lanosterol synthase (LSS) abnormity contributes to lens opacity in rats, mice, dogs, and human congenital cataract development. This study examined whether LSS pathway has a role in different subtypes of age-related cataract (ARC). Methods.
Xinyue Shen   +8 more
doaj   +1 more source

Metabolomics of dietary fatty acid restriction in patients with phenylketonuria [PDF]

open access: yes, 2012
Patients with phenylketonuria (PKU) have to follow a lifelong phenylalanine restricted diet. This type of diet markedly reduces the intake of saturated and unsaturated fatty acids especially long chain polyunsaturated fatty acids (LC-PUFA).
Berthold Koletzko   +10 more
core   +3 more sources

Sterol Metabolism and Transport in Atherosclerosis and Cancer

open access: yesFrontiers in Endocrinology, 2018
Cholesterol is a vital lipid molecule for mammalian cells, regulating fluidity of biological membranes, and serving as an essential constituent of lipid rafts. Mammalian cells acquire cholesterol from extracellular lipoproteins and from de novo synthesis.
Yoshio Yamauchi   +2 more
doaj   +1 more source

Vitamin D in plants: a review of occurrence, analysis, and biosynthesis. [PDF]

open access: yes, 2013
The major function of vitamin D in vertebrates is maintenance of calcium homeostasis, but vitamin D insufficiency has also been linked to an increased risk of hypertension, autoimmune diseases, diabetes and cancer. Therefore, there is a growing awareness
Jakobsen, Jette, Jäpelt, Rie Bak
core   +2 more sources

Development of an analytical method for detecting triterpene alcohols in camellia oil and evaluation of their anti‐inflammatory effects

open access: yesJSFA reports, EarlyView.
Abstract Background Camellia oil is a characteristic Chinese plant oil and is hailed as “the olive oil of the East”. However, there is a significant difference in the active ingredient between it and olive oil, which consequently leads to different effects.
Hengguang Cheng   +5 more
wiley   +1 more source

Triterpenoids from The Bark of Garcinia porecta and their Cytotoxic Activity against MCF7 Breast Cancer Lines

open access: yesAlchemy, 2019
The Garcinia genus is a well known tropical plant in the Indo-Malesiana region and mainly distributed in tropical countries including Indonesia, Thailand, and Malaysia. Previous phytochemical studies on Garcinia species have led to the identification and
Darwati Darwati   +6 more
doaj   +1 more source

Azole antifungal contaminants disrupt mycorrhizal function and risk agricultural sustainability

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Global food production is increasingly threatened by soil degradation, climate change and the rising costs of synthetic fertilisers. Circular agriculture, which promotes resource reuse, is a promising solution, but using treated wastewater and biosolids in farming introduces risks from emerging contaminants like pharmaceutical residues.
Emily K. Durant   +5 more
wiley   +1 more source

Bioinspired Synthesis of Twin abeo‐Steroids Bufogargarizins A and B via a Divergent Intramolecular Aldol Addition Reaction

open access: yesAngewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Twin natural products. This manuscript describes a concise biomimetic synthesis of twin abeo‐steroids bufogargarizins A and B with an unusual [7.5.6.5] and [5.7.6.5] skeletons in 19 steps (LLS). The described synthetic approach features the application of a bioinspired regiodivergent intramolecular aldol addition reaction and a selective singlet oxygen‐
Zoey J. Surma   +7 more
wiley   +2 more sources

Data on molecular docking of tautomers and enantiomers of ATTAF-1 and ATTAF-2 selectivty to the human/fungal lanosterol-14α-demethylase

open access: yesData in Brief, 2020
The data have been obtained for tautomers and enantiomers of ATTAF-1 and ATTAF-2 that were developed based on antifungal standard drugs with triazole scaffold. These compounds were docked into the human and fungal lanosterol-14α-demethylase.
Hamid Irannejad   +3 more
doaj   +1 more source

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