Results 71 to 80 of about 17,586 (206)

Mycochemical Diversity and Therapeutic Potential of Hymenochaetoid Fungi from Central Asia: Regional and Global Perspectives

New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov, Milena Rašeta, Sylvie Rapior, Manzura Yarasheva, Oksana Mykchaylova, Rustamjon Allaberdiev, Şule İnci, Dilfuza Berdieva, Arshad Mehmood Abbasi, Shikhnazar Khodjaev, Dian‐Ming Hu, Weijun Yang, Abudujilili Abuduaini, Maria Letizia Taddei, Mengcen Wang, Islomjon Urinboev, Jiajia Chen   +16 more
wiley   +1 more source

Isoprenoids increase bovine endometrial stromal cell tolerance to the cholesterol-dependent cytolysin from Trueperella pyogenes† [PDF]

, 2018
Preventing postpartum uterine disease depends on the ability of endometrial cells to tolerate the presence of the bacteria that invade the uterus after parturition.
Amos, Ayres, Bergstrom, Bergstrom, Bicalho, Billington, Bloch, Bonnett, Bustin, Christian, Cronin, Forman, Fukuchi, Gan, Gareth D Healey, Goldstein, Goldstein, Gonzalez, Griffin, Gurcel, Hardie, Healy, Hiyoshi, Huffman, I Martin Sheldon, Jost, Kalaany, Karstrup, Keller, Lange, LeBlanc, LeBlanc, Liao, Maxfield, McCusker, Mihaylova, Moore, Morgan, Mosmann, Park, Peraro, Preta, Preta, Read, Repa, Schneider, Sharpe, Sheldon, Sheldon, Sholeem Griffin, Statt, Turner, Turner, Tweten, Vander Heiden, Wang, Wathes, Westermann, Zoncu, Zwald   +59 more
core   +1 more source

NUDT21‐mediated Alternative Polyadenylation of CDK19 Reprograms Cholesterol Biosynthesis to Drive Colorectal Cancer Progression

Advanced Science, Volume 13, Issue 7, 3 February 2026.
NUDT21 is overexpressed in colorectal cancer tumors and promotes colorectal cancer progression. NUDT21 promotes the production of a cyclin‐dependent kinase 19 (CDK19) mRNA isoform with a long 3′ UTR, which enhances cytoplasmic export and translation. Truncation of the CDK19 long 3′ UTR phenocopies NUDT21 loss, recapitulating the defects in cholesterol ...
Yeping Yu, Jixin Ma, Minwei Zhou, Xiaodong Gu, Yiming Zhou, Zhenyang Li, Tianyu Zhang, Wei Gong, Chuanxin Huang, Jianbin Xiang   +9 more
wiley   +1 more source

A genome-wide association meta-analysis of cholesterol synthesis intermediates identifies three associations for lanosterolResearch in context

EBioMedicine
Summary: Background: Cholesterol is a main contributor to coronary artery disease (CAD). Although the genetic basis of blood cholesterol concentration is well studied, there is currently a lack of studies investigating the genetics of its precursors ...
Franz Förster, Katrin Horn, Janne Pott, Graciela E. Delgado, Marcus E. Kleber, Winfried März, Angela Patricia Moissl-Blanke, Günther Silbernagel, Melanie Waldenberger, Harald Grallert, Annette Peters, Christian Gieger, Ronny Baber, Holger Kirsten, Markus Loeffler, Berend Isermann, Joachim Thiery, Peter Kovacs, Anke Tönjes, Michael Stumvoll, Helena Gylling, Mika Kähönen, Terho Lehtimäki, Pashupati Prasad Mishra, Olli Raitakari, Uta Ceglarek, Markus Scholz   +26 more
doaj   +1 more source

Inhibition of cholesterol biogenesis by arsenite: preparation of labeled lanosterol*

Journal of Lipid Research, 1961
When mevalonic acid-2-C14 was incubated with rat liver homogenate with the usual cofactors plus 10−3 M arsenite, the formation of labeled cholesterol was inhibited and labeled lanosterol accumulated.
Mary L. Moller, T.T. Tchen
doaj   +1 more source

Molecular Identification and Evaluation of Resistance to Antifungal Drugs in Candida Species Isolated From Diaper Rash of Neonates

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Diaper dermatitis, also recognized as diaper rash, is one of the most frequent skin conditions in neonates. Materials and Methods A total of 100 babies participated in the study. Eligibility included neonates aged 5–28 days and full‐time diaper wearers.
Fariba Shirvani, Mahsa Fattahi, Abdollah Karimi, Shahnaz Armin, Seyed Alireza Fahimzad, Sedigheh Rafiei Tabatabaei, Roxana Mansour Ghanaei, Fatemeh Fallah, Alireza Firooz, Shahrzad Tabatabaee, Mitra Radfar, Dorsa Kalani, Hossein Foroozan, Afagh firoozgaeean Galoogah, Pegah Tamimi   +14 more
wiley   +1 more source

Study on anti-tumor activity of itraconazole in colon cancer [PDF]

E3S Web of Conferences, 2019
Itraconazole is a common antifungal drug, which inhibiting lanosterol 14 alpha-demethylase, interfering with lanosterol convert to ergosterol or cholesterol, thereby affecting the synthesis of fungal cell membranes.
Li Xiaoqi, Shan Jingbo, Jin Lijun, Li Xinyu, Zhou Sa, Ma Wenjian   +5 more
doaj   +1 more source

Cholesterol and nicotinic acetylcholine receptor: An intimate nanometer-scale spatial relationship spanning the billion year time-scale [PDF]

, 2016
Once the sterol biosynthetic machinery had progressed over the course of several million years to yield cholesterol, this neutral lipid became an omnipresent and essential component of biomembranes in Eukaryotes.
Barrantes, Francisco Jose
core   +1 more source

Emergence of Candida (Candidozyma) auris in Minas Gerais, Brazil: Genomic Surveillance to Guide Rapid Public Health Responses

Mycoses, Volume 69, Issue 2, February 2026.
ABSTRACT Background Candida (Candidozyma) auris is an emerging yeast that poses a significant global health threat due to its multidrug resistance and ability to cause healthcare‐associated outbreaks. Genomic surveillance is essential for monitoring spread, transmission and antifungal resistance.
Luiz Marcelo Ribeiro Tomé, Dhian Renato Almeida Camargo, Rafael Wesley Bastos, Sara Cândida Ferreira dos Santos, Natália Rocha Guimarães, Sílvia Helena Sousa Pietra Pedroso, Paulo Eduardo de Souza da Silva, Aristóteles Góes‐Neto, Lida Jouca de Assis Figueredo, Gabriella da Côrte Castro, Ana Maria Ribeiro Nunes Rodrigues, Flavia Ribeiro Soares Cruzeiro, Nádia Aparecida Campos Dutra, Josiane Barbosa Piedade Moura, Glauco de Carvalho Pereira, Carmem Dolores Faria, Marta Giovanetti, Felipe Campos de Melo Iani, Luiz Carlos Júnior Alcantara, Talita Émile Ribeiro Adelino   +19 more
wiley   +1 more source

Lanosterol regulates abnormal amyloid accumulation in LECs through the mediation of cholesterol pathway metabolism

Biochemistry and Biophysics Reports
Age-related cataract (ARC) is the predominant cause of global blindness, linked to the progressive aging of the lens, oxidative stress, perturbed calcium homeostasis, hydration irregularities, and modifications in crystallin proteins. Currently, surgical
Yingxue Su, Danyuan Sun, Chen Cao, Yandong Wang   +3 more
doaj   +1 more source