Results 21 to 30 of about 6,528 (248)

Insights in the Antimicrobial Potential of the Natural Nisin Variant Nisin H

Frontiers in Microbiology, 2020
Lantibiotics are a growing class of antimicrobial peptides, which possess antimicrobial activity against mainly Gram-positive bacteria including the highly resistant strains such as methicillin-resistant Staphylococcus aureus or vancomycin-resistant ...
Jens Reiners, Jens Reiners, Marcel Lagedroste, Julia Gottstein, Emmanuel T. Adeniyi, Rainer Kalscheuer, Gereon Poschmann, Kai Stühler, Kai Stühler, Sander H. J. Smits, Sander H. J. Smits, Lutz Schmitt   +11 more
doaj   +1 more source

The N-terminal Region of Nisin Is Important for the BceAB-Type ABC Transporter NsrFP from Streptococcus agalactiae COH1

Frontiers in Microbiology, 2017
Lantibiotics are (methyl)-lanthionine-containing antimicrobial peptides produced by several Gram-positive bacteria. Some human pathogenic bacteria express specific resistance proteins that counteract this antimicrobial activity of lantibiotics.
Jens Reiners, Marcel Lagedroste, Katja Ehlen, Selina Leusch, Julia Zaschke-Kriesche, Sander H. J. Smits   +5 more
doaj   +1 more source

Potentiating the activity of nisin against Escherichia coli

Frontiers in Cell and Developmental Biology, 2016
Lantibiotics are antimicrobial (methyl) lanthionine-containing peptides produced by various Gram-positive bacteria. The model lantibiotic, nisin, binds lipid II in the cell membrane.
Liang eZhou, Auke J. van Heel, Manuel eMontalban-Lopez, Oscar P. Kuipers   +3 more
doaj   +1 more source

Antimicrobial antagonists against food pathogens; a bacteriocin perspective [PDF]

, 2015
peer-reviewedEfforts are continuing to find novel bacteriocins with enhanced specificity and potency. Traditional plating techniques are still being used for bacteriocin screening studies, however, the availability of ever more bacterial genome sequences
Cotter, Paul D., Hill, Colin, O'Connor, Paula M., Ross, R Paul   +3 more
core   +1 more source

Subcellular Localization and Assembly Process of the Nisin Biosynthesis Machinery in Lactococcus lactis

mBio, 2020
Nisin, a class I lantibiotic, is synthesized as a precursor peptide by a putative membrane-associated lanthionine synthetase complex consisting of the dehydratase NisB, the cyclase NisC, and the ABC transporter NisT. Here, we characterize the subcellular
Jingqi Chen, Auke J. van Heel, Oscar P. Kuipers   +2 more
doaj   +1 more source

Bioprocess Development for Lantibiotic Ruminococcin-A Production in Escherichia coli and Kinetic Insights Into LanM Enzymes Catalysis [PDF]

, 2019
Ruminococcin-A (RumA) is a peptide antibiotic with post-translational modifications including thioether cross-links formed from non-canonical amino acids, called lanthionines, synthesized by a dedicated lanthionine-generating enzyme RumM.
Adrian, Lorenz, Neubauer, Peter, Ongey, Elvis L., Riedel, Sebastian L., Santolin, Lara, Waldburger, Saskia   +5 more
core   +1 more source

Kunkecin A, a New Nisin Variant Bacteriocin Produced by the Fructophilic Lactic Acid Bacterium, Apilactobacillus kunkeei FF30-6 Isolated From Honey Bees

Frontiers in Microbiology, 2020
Apilactobacillus kunkeei FF30-6 isolated from healthy honey bees synthesizes the bacteriocin, which exhibits antimicrobial activity against Melissococcus plutonius.
Takeshi Zendo, Chihiro Ohashi, Shintaro Maeno, Xingguo Piao, Seppo Salminen, Kenji Sonomoto, Akihito Endo   +6 more
doaj   +1 more source

Microbisporicin (NAI-107) protects Galleria mellonella from infection with Neisseria gonorrhoeae

Microbiology Spectrum, 2023
Due to the increasing incidence of antibiotic-resistant bacterial pathogens, the need for the development of alternative compounds is of utmost importance. Bacteriocins are considered a promising alternative to antibiotics.
Nele Hofkens, Zina Gestels, Said Abdellati, Irith De Baetselier, Philippe Gabant, Anandi Martin, Christopher Kenyon, Sheeba Santhini Manoharan-Basil   +7 more
doaj   +1 more source

Design and Expression of Specific Hybrid Lantibiotics Active Against Pathogenic Clostridium spp.

Frontiers in Microbiology, 2019
Clostridium difficile has been reported as the most common cause of nosocomial diarrhea (antibiotic-associated diarrhea), resulting in significant morbidity and mortality in hospitalized patients.
Rubén Cebrián, Alicia Macia-Valero, Afif P. Jati, Oscar P. Kuipers   +3 more
doaj   +1 more source

Immobilization of Bacteriocins from Lactic Acid Bacteria and Possibilities for Application in Food Biopreservation [PDF]

, 2018
Bacteriocins are biologically active compounds produced by a large number of bacteria, including lactic acid bacteria (LAB), which exhibit antimicrobial activity against various saprophytic and pathogenic microorganisms.
Krastanov, Albert, Lante, Anna, Tumbarski, Yulian   +2 more
core   +1 more source