Results 31 to 40 of about 6,528 (248)

Lantibiotics from Geobacillus thermodenitrificans [PDF]

Proceedings of the National Academy of Sciences, 2012
The lantibiotic nisin has been used as an effective food preservative to combat food-borne pathogens for over 40 y. Despite this successful use, nisin’s stability at pH 7 is limited. Herein, we describe a nisin analog encoded on the genome of the thermophilic bacterium Geobacillus thermodenitrificans NG80-2.
Neha, Garg, Weixin, Tang, Yuki, Goto, Satish K, Nair, Wilfred A, van der Donk   +4 more
openaire   +2 more sources

Diverse Bacteriocins Produced by Strains From the Human Milk Microbiota

Frontiers in Microbiology, 2020
Microbial colonization of the infant gut is a convoluted process dependent on numerous contributing factors, including age, mode of delivery and diet among others that has lifelong implication for human health.
Angeliki Angelopoulou, Angeliki Angelopoulou, Alicja K. Warda, Paula M. O’Connor, Paula M. O’Connor, Stephen R. Stockdale, Andrey N. Shkoporov, Des Field, Des Field, Lorraine A. Draper, Catherine Stanton, Catherine Stanton, Colin Hill, Colin Hill, R. Paul Ross, R. Paul Ross, R. Paul Ross   +16 more
doaj   +1 more source

Probiotics and Their Antimicrobial Metabolites: A Collegial Strategy for Food Bio-Preservation - A Review. [PDF]

Food Sci Nutr
Illustrates the potential of probiotics and their antimicrobial metabolites in food bio‐preservation. ABSTRACT Ensuring food safety and extending the shelf life of perishable products remain major challenges for the global food industry. The escalating consumer demand for natural food preservatives has intensified research into biological alternatives ...
Wang L, Ren S, Behan AA, Arain MA, Ujjan NA, Zeng D, Li Y, Ma X.   +7 more
europepmc   +2 more sources

In Vitro Activities of Nisin and Nisin Derivatives Alone and In Combination with Antibiotics against Staphylococcus Biofilms [PDF]

, 2016
peer-reviewedThe development and spread of pathogenic bacteria that are resistant to the existing catalog of antibiotics is a major public health threat.
Cotter, Paul D., Field, Des, Hill, Colin, O'Connor, Rory, Ross, R Paul   +4 more
core   +1 more source

Evaluation of analogs of mutacin 1140 in systemic and cutaneous methicillin-resistant Staphylococcus aureus infection models in mice

Frontiers in Microbiology, 2022
Mutacin 1140 (Mu1140) is a potent antibiotic against Gram-positive bacteria, such as Staphylococcus aureus. The antibiotic is produced by the oral bacterium Streptococcus mutans and is a member of the epidermin family of type AI lantibiotics.
Min Ju, Thushinari Joseph, Nopakorn Hansanant, Mengxin Geng, McKinley Williams, Andrew Cothrell, Andrew Riley Buhrow, Andrew Riley Buhrow, Frank Austin, Leif Smith, Leif Smith   +10 more
doaj   +1 more source

In silico identification of bacteriocin gene clusters in the gastrointestinal tract, based on the Human Microbiome Project’s reference genome database [PDF]

, 2015
peer-reviewedBackground The human gut microbiota comprises approximately 100 trillion microbial cells which significantly impact many aspects of human physiology - including metabolism, nutrient absorption and immune function ...
Cotter, Paul D., Guinane, Caitriona M., Hill, Colin, O'Toole, Paul W., Ross, R Paul, Walsh, Calum J.   +5 more
core   +1 more source

Cyclo19,31[D-Cys19]-uPA19-31 is a potent competitive antagonist of the interaction of urokinase-type plasminogen activator with its receptor (CD87) [PDF]

, 2001
Urokinase-type plasminogen activator (uPA) represents a central molecule in pericellular proteolysis and is implicated in a variety of physiological and pathophysiological processes such as tissue remodelling, wound healing, tumor invasion, and ...
Arroyo de Prada, Nuria, Bürgle, Markus, Degitz, Klaus, Kellermann, Josef, Kessler, Horst, Magdolen, Viktor, Riemer, Christoph, Schmiedeberg, Niko, Schmitt, Manfred, Schroeck, Florian, Wilhelm, Olaf G.   +10 more
core   +1 more source

Tonsillar Microbiome‐Derived Lantibiotics Induce Structural Changes of IL‐6 and IL‐21 Receptors and Modulate Host Immunity

Advanced Science, 2022
Emerging evidence emphasizes the functional impacts of host microbiome on the etiopathogenesis of autoimmune diseases, including rheumatoid arthritis (RA).
Jing Li, Jiayang Jin, Shenghui Li, Yan Zhong, Yuebo Jin, Xuan Zhang, Binbin Xia, Yinhua Zhu, Ruochun Guo, Xiaolin Sun, Jianping Guo, Fanlei Hu, Wenjing Xiao, Fei Huang, Hua Ye, Ru Li, Yunshan Zhou, Xiaohong Xiang, Haihong Yao, Qiulong Yan, Li Su, Lijun Wu, Tuoping Luo, Yudong Liu, Xiaohuan Guo, Junjie Qin, Hai Qi, Jing He, Jun Wang, Zhanguo Li   +29 more
doaj   +1 more source

Bacteriocins: Novel Solutions to Age Old Spore-Related Problems? [PDF]

, 2016
peer-reviewedBacteriocins are ribosomally synthesized antimicrobial peptides produced by bacteria, which have the ability to kill or inhibit other bacteria. Many bacteriocins are produced by food grade lactic acid bacteria (LAB).
Cotter, Paul D., Egan, Kevin, Field, Des, Hill, Colin, Rea, Mary, Ross, R Paul   +5 more
core   +1 more source

Quorum sensing in group A streptococcus

Frontiers in Cellular and Infection Microbiology, 2014
Quorum sensing is a widespread phenomenon in the microbial world that has important implications in the coordination of population-wide responses in several bacterial pathogens.
Michael J. Federle, Juan Cristobal Jimenez   +1 more
doaj   +1 more source