Results 51 to 60 of about 6,528 (248)
Lantibiotics are ribosomally synthesized (methyl)lanthionine containing peptides which can efficiently inhibit the growth of Gram-positive bacteria. As lantibiotics kill bacteria efficiently and resistance to them is difficult to be obtained, they have ...
Liang eZhou +2 more
doaj +1 more source
Engineering Dehydrated Amino Acid Residues in the Antimicrobial Peptide Nisin [PDF]
The small antimicrobial peptide nisin, produced by Lactococcus lactis, contains the uncommon amino acid residues dehydroalanine and dehydrobutyrine and five thio ether bridges.
Boot, Hein J., +5 more
core +1 more source
Fracturing Rings to Understand Lantibiotics
Haloduracin is a bacterially produced antibiotic system of two alkali-stable peptides (Halalpha and Halbeta) that have extensive posttranslational modifications, including lanthionine rings. Now, Cooper et al. (2008) revise the structure of Halbeta and demonstrate that some of the lanthionine rings are not essential for bioactivity.
Yoganathan, Sabesan, Vederas, John C.
openaire +2 more sources
Influence of antioxidants‐loaded biopolymer films on food security and extended shelf life. ABSTRACT Autooxidation is a significant cause of quality deterioration in food systems, leading to nutrient loss, off‐flavor formation, textural changes, and overall spoilage.
Sai Kumar Tammina +5 more
wiley +1 more source
A method was established for the production of 1.2-fold and 4.2-fold increased amounts of the antiviral and central nervous system-active lantipeptides, labyrinthopeptins A1 and A2, respectively, isolated from the actinobacterium Actinomadura namibiensis,
Zeljka Rupcic +4 more
doaj +1 more source
Probiogenomic and in vitro analyses revealed that Lacticaseibacillus paracasei UFTM 2.9 does not exhibit virulence determinants, produces inhibitory compounds against pathogenic bacteria, and possesses 170 genes associated with probiotics, which corroborates its metabolic versatility and potential for survival and functionality in the gastrointestinal ...
Bárbara R. Fonseca +10 more
wiley +1 more source
Lantibiotics as prospective antimycobacterial agents [PDF]
Mycobacteria contribute substantially to human infectious disease, most notably the primary pathogens of tuberculosis (TB), leprosy and Bureli ulcer. Global prospects for TB control are challenged by the emergence of drug-resistant strains. If we are to stay ahead of mycobacterial strains developing resistance to chemotherapeutic regimens, all new ...
openaire +2 more sources
Background. Streptococcus salivarius K12 (SsK12) is an oral colonizing, persistent, antibiotic-sensitive and safe strain that produces two megaplasmid-encoded class I lantibiotics, namely salivaricin A2 and salivaricin B, which expression inhibits the ...
T.O. Kryuchko, O.Ya. Tkachenko
doaj +1 more source
Quorum sensing-controlled gene expression in lactic acid bacteria [PDF]
Quorum sensing in lactic acid bacteria (LAB) involves peptides that are directly sensed by membrane-located histidine kinases, after which the signal is transmitted to an intracellular response regulator. This regulator in turn activates transcription of
Brurberg +25 more
core +2 more sources
Dysbiosis in the Pathogenesis of Atopic Dermatitis
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by epidermal barrier dysfunction and immune dysregulation. Recent research highlights cutaneous dysbiosis as a critical factor in its pathogenesis. In this review, we summarize the interplay between the skin microbiota and host immunity, contrasting the homeostatic ...
Hiroki Okamoto, Yuumi Nakamura
wiley +1 more source

