Results 51 to 60 of about 6,528 (248)

The length of a lantibiotic hinge region has profound influence on antimicrobial activity and host specificity

open access: yesFrontiers in Microbiology, 2015
Lantibiotics are ribosomally synthesized (methyl)lanthionine containing peptides which can efficiently inhibit the growth of Gram-positive bacteria. As lantibiotics kill bacteria efficiently and resistance to them is difficult to be obtained, they have ...
Liang eZhou   +2 more
doaj   +1 more source

Engineering Dehydrated Amino Acid Residues in the Antimicrobial Peptide Nisin [PDF]

open access: yes, 1992
The small antimicrobial peptide nisin, produced by Lactococcus lactis, contains the uncommon amino acid residues dehydroalanine and dehydrobutyrine and five thio ether bridges.
Boot, Hein J.,   +5 more
core   +1 more source

Fracturing Rings to Understand Lantibiotics

open access: yesChemistry & Biology, 2008
Haloduracin is a bacterially produced antibiotic system of two alkali-stable peptides (Halalpha and Halbeta) that have extensive posttranslational modifications, including lanthionine rings. Now, Cooper et al. (2008) revise the structure of Halbeta and demonstrate that some of the lanthionine rings are not essential for bioactivity.
Yoganathan, Sabesan, Vederas, John C.
openaire   +2 more sources

A Comprehensive Review on the Significance of Antioxidants and Their Influence on Biopolymer Packaging Films: Recent Advances and Challenges

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
Influence of antioxidants‐loaded biopolymer films on food security and extended shelf life. ABSTRACT Autooxidation is a significant cause of quality deterioration in food systems, leading to nutrient loss, off‐flavor formation, textural changes, and overall spoilage.
Sai Kumar Tammina   +5 more
wiley   +1 more source

Large Scale Production and Downstream Processing of Labyrinthopeptins from the Actinobacterium Actinomadura namibiensis

open access: yesBioengineering, 2018
A method was established for the production of 1.2-fold and 4.2-fold increased amounts of the antiviral and central nervous system-active lantipeptides, labyrinthopeptins A1 and A2, respectively, isolated from the actinobacterium Actinomadura namibiensis,
Zeljka Rupcic   +4 more
doaj   +1 more source

Unveiling the Probiotic Properties of Lacticaseibacillus paracasei UFTM 2.9 Through Probiogenomic Analysis

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 6, 29 March 2026.
Probiogenomic and in vitro analyses revealed that Lacticaseibacillus paracasei UFTM 2.9 does not exhibit virulence determinants, produces inhibitory compounds against pathogenic bacteria, and possesses 170 genes associated with probiotics, which corroborates its metabolic versatility and potential for survival and functionality in the gastrointestinal ...
Bárbara R. Fonseca   +10 more
wiley   +1 more source

Lantibiotics as prospective antimycobacterial agents [PDF]

open access: yesBioengineered Bugs, 2010
Mycobacteria contribute substantially to human infectious disease, most notably the primary pathogens of tuberculosis (TB), leprosy and Bureli ulcer. Global prospects for TB control are challenged by the emergence of drug-resistant strains. If we are to stay ahead of mycobacterial strains developing resistance to chemotherapeutic regimens, all new ...
openaire   +2 more sources

Clinical experience of Streptococcus salivarius K12 use for the prevention of pharyngotonsillitis and respiratory infections in children

open access: yesZdorovʹe Rebenka, 2018
Background. Streptococcus salivarius K12 (SsK12) is an oral colonizing, persistent, antibiotic-sensitive and safe strain that produces two megaplasmid-encoded class I lantibiotics, namely salivaricin A2 and salivaricin B, which expression inhibits the ...
T.O. Kryuchko, O.Ya. Tkachenko
doaj   +1 more source

Quorum sensing-controlled gene expression in lactic acid bacteria [PDF]

open access: yes, 1998
Quorum sensing in lactic acid bacteria (LAB) involves peptides that are directly sensed by membrane-located histidine kinases, after which the signal is transmitted to an intracellular response regulator. This regulator in turn activates transcription of
Brurberg   +25 more
core   +2 more sources

Dysbiosis in the Pathogenesis of Atopic Dermatitis

open access: yesThe Journal of Dermatology, Volume 53, Issue 3, Page 388-398, March 2026.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by epidermal barrier dysfunction and immune dysregulation. Recent research highlights cutaneous dysbiosis as a critical factor in its pathogenesis. In this review, we summarize the interplay between the skin microbiota and host immunity, contrasting the homeostatic ...
Hiroki Okamoto, Yuumi Nakamura
wiley   +1 more source

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