Results 101 to 110 of about 16,901 (224)

Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage [PDF]

open access: yes, 2010
Background Several arenaviruses cause severe hemorrhagic fever and aseptic meningitis in humans for which no licensed vaccines are available. A major obstacle for vaccine development is pathogen heterogeneity within the Arenaviridae family.
Maya F Kotturi   +12 more
core   +2 more sources

Outbreak of lassa fever in Nigeria: measures for prevention and control

open access: yesThe Pan African Medical Journal, 2016
Lassa fever, an acute viral haemorrhagic fever, extremely virulent and often infectious, occurs very frequently in different parts of Nigeria [1-4] and affects approximately 100,000-500,000 persons per year in West Africa.
Kehinde Charles Mofolorunsho
doaj   +1 more source

Arbovirus infections and viral haemorrhagic fevers in Uganda : a serological survey in Karamoja district, 1984 [PDF]

open access: yes, 1989
Présentation des résultats de l'enquête effectuée sur 132 habitants du district de Karamoja en Ouganda, qui ont été examinés pour la recherche d'anticorps contre certains arbovirus dont la fièvre ...
Gonzalez, Jean-Paul   +5 more
core   +1 more source

Lassa fever in West African sub-region: an overview [PDF]

open access: yesJournal of Vector Borne Diseases, 2007
Lassa fever is an acute viral zoonotic illness caused by Lassa virus, an arenavirus known to beresponsible for a severe haemorrhagic fever characterised by fever, muscle aches, sore throat, nausea,vomiting and, chest and abdominal pain.
O. Ogbu, E. Ajuluchukwu, C.J. Uneke
doaj  

Infection of type I interferon receptor-deficient mice with various old world arenaviruses: a model for studying virulence and host species barriers.

open access: yesPLoS ONE, 2013
Lassa virus causes hemorrhagic Lassa fever in humans, while the related Old World arenaviruses Mopeia, Morogoro, and Mobala are supposedly apathogenic to humans and cause only inapparent infection in non-human primates.
Toni Rieger   +2 more
doaj   +1 more source

An Agent-Based Spatially Explicit Epidemiological Model in MASON [PDF]

open access: yes
This paper outlines the design and implementation of an agent-based epidemiological simulation system. The system was implemented in the MASON toolkit, a set of Java-based agent-simulation libraries.
Jill Bigley Dunham
core  

The role of myristoylation in the membrane association of the Lassa virus matrix protein Z

open access: yesVirology Journal, 2006
The Z protein is the matrix protein of arenaviruses and has been identified as the main driving force for budding. Both LCMV and Lassa virus Z proteins bud from cells in the absence of other viral proteins as enveloped virus-like particles. Z accumulates
Eichler Robert   +5 more
doaj   +1 more source

Development and Testing of the Method for the Detection of Lassa virus RNA, Based on real-Time Polymerase Chain reaction with reverse Transcription

open access: yesПроблемы особо опасных инфекций, 2018
. Objective of the study was the development of a method for the detection and quantitative analysis (realtime RT-PCR) to identify genetic markers of Lassa virus - LASV-Fl. Materials and methods.
V. G. Dedkov   +11 more
doaj   +1 more source

Emerging Challenges and Opportunities in Infectious Disease Epidemiology. [PDF]

open access: yes, 2019
Much of the intellectual tradition of modern epidemiology stems from efforts to understand and combat chronic diseases persisting through the 20th century epidemiologic transition of countries such as the United States and United Kingdom.
Lewnard, Joseph A, Reingold, Arthur L
core  

Innate and adaptive immune control of genetically engineered live-attenuated arenavirus vaccine prototypes [PDF]

open access: yes, 2017
Arenaviruses such as Lassa virus (LASV) cause significant morbidity and mortality in endemic areas. Using a glycoprotein (GP) exchange strategy, we have recently developed live-attenuated arenavirus vaccine prototypes (rLCMV/VSVG) based on lymphocytic ...
Bergthaler, Andreas   +7 more
core  

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