Results 61 to 70 of about 1,615,318 (318)
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
IEEE AccessThe rapid expansion of Internet of Things (IoT) devices in healthcare has increased data volumes, creating challenges for the efficiency and latency of real-time monitoring systems.
Mohammed Alaa Ala'anzy +4 more
doaj +1 more source
Bioactive molecules released from cells infected with the Human Cytomegalovirus
Frontiers in Microbiology, 2016 Following primary infection in humans, the Human Cytomegalovirus (HCMV) persists in a latent state throughout the host’s lifetime despite a strong and efficient immune response.
Anna eLuganini +2 more
doaj +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Cell Reports, 2017 Latent replication-competent HIV-1 persists in individuals on long-term antiretroviral therapy (ART). We developed the Full-Length Individual Proviral Sequencing (FLIPS) assay to determine the distribution of latent replication-competent HIV-1 within ...
Bonnie Hiener +18 more
doaj +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Frontiers in ImmunologyAfter primary infection with varicella, varicella-zoster virus (VZV) establishes a latent state that precedes the clinical manifestation of herpes zoster.
Dong-Gyun Han
doaj +1 more source
Interplay of Murine Gammaherpesvirus 68 with NF-kappaB Signaling of the Host
Frontiers in Microbiology, 2016 Herpesviruses establish a chronic infection in the host characterized by intervals of lytic replication, quiescent latency, and reactivation from latency.
Laurie T Krug +3 more
doaj +1 more source
Multi-CAP Assisted Intelligent Mobile Edge Computing Networks for Internet of Things
IEEE Access, 2020 In this paper, we investigate intelligent mobile edge computing networks (MEC) with multiple computational access points (CAPs) for Internet of Things (IoT), where the user with limited computational capability has some tasks to be computed with the help
Liming Chen +5 more
doaj +1 more source
Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu +16 more
wiley +1 more source