Results 161 to 170 of about 388,981 (242)

Schlafen 12 restricts HIV-1 latency reversal by a codon-usage dependent post-transcriptional block in CD4+ T cells. [PDF]

Commun Biol, 2023
Kobayashi-Ishihara M, Frazão Smutná K, Alonso FE, Argilaguet J, Esteve-Codina A, Geiger K, Genescà M, Grau-Expósito J, Duran-Castells C, Rogenmoser S, Böttcher R, Jungfleisch J, Oliva B, Martinez JP, Li M, David M, Yamagishi M, Ruiz-Riol M, Brander C, Tsunetsugu-Yokota Y, Buzon MJ, Díez J, Meyerhans A.   +22 more
europepmc   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

Interleukin-2 is a potent latency reversal agent in people with treated HIV-1. [PDF]

Sci Adv
Freeman ML, Clagett BM, Leskov K, Moisi D, Yendewa GA, Sieg SF, Laird GM, Karn J, Jacobson JM, Rodriguez B, Lederman MM.   +10 more
europepmc   +1 more source

Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C. [PDF]

Sci Adv, 2023
Soliman SHA, Cisneros WJ, Iwanaszko M, Aoi Y, Ganesan S, Walter M, Zeidner JM, Mishra RK, Kim EY, Wolinsky SM, Hultquist JF, Shilatifard A.   +11 more
europepmc   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

Harziachalasins A-G, polycyclic-fused cytochalasins from the endophytic fungus Trichoderma harzianum MLJ-4 with HIV latency reversal activity. [PDF]

Nat Prod Bioprospect
Zhang YJ, Yang XY, Fu YF, Liao Q, Chen JQ, Chen XA, Huang D, Yuan T, Chen X, Yin S, Tang GH.   +10 more
europepmc   +1 more source

Defining stable reference genes in HIV latency reversal experiments. [PDF]

J Virol, 2021
Ceriani C, Streeter GS, Lemu KJ, James KS, Ghofrani S, Allard B, Shook-Sa BE, Margolis DM, Archin NM.   +8 more
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

The effect of combining HIV latency reversal with inhibition of phosphoinositide-3 kinases or B-cell lymphoma-2 on the HIV reservoir. [PDF]

PLoS Pathog
Kim Y, Anderson JL, Tumpach C, Solomon A, Ong J, Tanaka K, Zerbato JM, Tan T, Teh CE, Gray DHD, Arandjelovic P, McMahon J, Meagher N, Price D, Pellegrini M, Roche M, Lewin SR.   +16 more
europepmc   +1 more source

Off-Target Effect of Activation of NF-κB by HIV Latency Reversal Agents on Transposable Elements Expression. [PDF]

Viruses, 2022
Curty G, Iniguez LP, Soares MA, Nixon DF, de Mulder Rougvie M.   +4 more
europepmc   +1 more source