Results 121 to 130 of about 106,553 (247)

Pathogenesis, Immunology, and Diagnosis of Latent Mycobacterium tuberculosis Infection

Clinical and Developmental Immunology, 2011
Phagocytosis of tubercle bacilli by antigen-presenting cells in human lung alveoli initiates a complex infection process by Mycobacterium tuberculosis and a potentially protective immune response by the host. M.
Suhail Ahmad
doaj   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

The Dual Immunoregulatory Role of CREB3L1 Underlying Latent and Severe Tuberculosis Clinical Manifestation

Immunology, Volume 177, Issue 4, Page 810-823, April 2026.
RNA‐seq of lungs and livers from Mycobacterium tuberculosis ‐infected mice with distinct disease outcomes revealed organ‐specific responses driven by differences in immune activity and bacterial burden. Meta‐analysis identified orthologous genes shared with human latent TB and mouse liver, with Creb3l1, Myo7b, Cyyr1 and Cbs differentially expressed and
Felipe T. Lima, Ricardo C. Castro, Francisco R. Javier, Caroline Fontanari, Valdes R. Bollela, Rogerio S. Rosada, Célio L. Silva, Lúcia H. Faccioli, Luiz G. Gardinassi, Fabiani G. Frantz   +9 more
wiley   +1 more source

Mortality from cancer and non‐cancer diseases in the Lithuanian cohort of Chernobyl cleanup workers (2001–2020)

International Journal of Cancer, Volume 158, Issue 6, Page 1498-1506, 15 March 2026.
What's new? Following the Chernobyl disaster, workers were recruited from formerly Soviet‐occupied areas, including Lithuania, to participate in clean‐up efforts. Radiation exposure incurred by workers during these efforts offers a unique opportunity for the study of long‐term health effects.
Rita Steponaviciene, Ausrele Kesminiene, Auguste Kaceniene, Giedre Smailyte   +3 more
wiley   +1 more source

Sparse Probit Linear Mixed Model

, 2017
Linear Mixed Models (LMMs) are important tools in statistical genetics. When used for feature selection, they allow to find a sparse set of genetic traits that best predict a continuous phenotype of interest, while simultaneously correcting for various ...
Cunningham, John P., Kloft, Marius, Lippert, Christoph, Mandt, Stephan, Nakajima, Shinichi, Wenzel, Florian   +5 more
core   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, Volume 15, Issue 10, 13 March 2026.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Paucibacillary Pleural Tuberculosis Presenting as Subpleural Nodules: A Diagnostic Challenge With Negative PCR and Smear Tests

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Pleural tuberculosis is a common manifestation of extrapulmonary tuberculosis; however, its diagnosis remains challenging in paucibacillary disease, where clinical presentation may be atypical and microbiological tests frequently yield negative results.
Omar Al Ayoubi, Mohammad Alaa Aldakak, Bassel Ibrahim, Raneem Ahmad, Youness Souleiman   +4 more
wiley   +1 more source

Passive Versus Active Tuberculosis Case Finding and Isoniazid Preventive Therapy Among Household Contacts in a Rural District of Malawi. [PDF]

, 2003
SETTING: Thyolo district, rural Malawi. OBJECTIVES: To compare passive with active case finding among household contacts of smear-positive pulmonary tuberculosis (TB) patients for 1) TB case detection and 2) the proportion of child contacts aged under 6 ...
Bakali, E, Gomani, P, Graham, S, Harries, A D, Humblet, P, Spielmann M P, Zachariah, R   +6 more
core   +1 more source

Tuberculosis Presenting as Migratory Arthritis: A Case Report from Iraq

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Extrapulmonary tuberculosis is uncommon, and musculoskeletal involvement presenting as migratory arthritis is particularly rare in immunocompetent individuals, often leading to misdiagnosis and delayed treatment. We report the case of a 66‐year‐old man with diabetes mellitus who presented with recurrent migratory inflammatory arthritis ...
Farah Jaafar Mahdi, Mariam Salem Othman, Ahmed Dheyaa Al‐Obaidi, Mustafa Almusawi, Marafi Jammaa Ahmed, Aya Ahmed Shimal, Elian Khalafalla Awadalla, Marwah Algodi   +7 more
wiley   +1 more source

Holmes Tremor Following Thalamic Tuberculoma—A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Tremor is the most common movement disorder, defined as a rhythmical oscillatory involuntary movement that can affect almost any body part. Holmes Tremor (HT) is an irregular, slow‐frequency (< 4.5 Hz) tremor that may include one or a combination of resting, postural, and action tremors.
Abera Kuma, Amanuel Anegagregn, Misganaw Yiglete Damte, Adugna Getahun Deboch, Yishak Endalew, Melat Demisse, Yegzeru Belete   +6 more
wiley   +1 more source