Results 51 to 60 of about 56,167 (240)

Association between hematological inflammatory markers and latent TB infection: insights from NHANES 2011–2012 and transcriptomic data

Frontiers in Cellular and Infection Microbiology
BackgroundLatent tuberculosis infection affects about one-quarter of the global population and can progress to active tuberculosis. Hematological inflammatory markers, such as the systemic immune-inflammation index, neutrophil-to-lymphocyte ratio ...
Yang Liu, Chunyan He, He Zhao, Weiyao Zhong, Shihua Sun, Zhuo Li, Jingwei Shi   +6 more
doaj   +1 more source

Transformative Pathways for Strengthening Climate‐Resilient Health Systems Among Indigenous Communities: Advancing Equity and Sustainability in Global Health

Sustainable Development, EarlyView.
ABSTRACT Most climate‐resilience health interventions are designed at the global level, with minimal attention to Indigenous communities' needs. The lack of consideration can lead to unintended harm and exacerbate health risks. This study aims to identify the capacities of Indigenous communities that can serve as transformative pathways in safely ...
Chrishma D. Perera, Eranga K. Galappaththi, Carol Zavaleta‐Cortijo, Timothy D. Baird, Korine N. Kolivras, James D. Ford, Michelle Dickson, Kerrie Pickering, Guangqing Chi, Joana Bezerra, Dhanya Vijayan, Victoria Chicamana‐Zapata, Cecil Togarepi, Kheminda G. Thilakarathne, Martha M. Hangula, Francis A. Akugre, Richard Nuwagira, Jonathan Nkalubo   +17 more
wiley   +1 more source

Tuberculosis State Is Associated with Expression of Toll-Like Receptor 2 in Sputum Macrophages

mSphere, 2017
During tuberculosis, macrophages are critical for both pathogen survival and host immune activation. Since expression of particular cell surface markers reflects cell function, we used flow cytometry to measure the abundance of surface markers associated
Karim Lakehal, David Levine, Kathleen F. Kerr, Pooja Vir, Natalie Bruiners, Alfred Lardizabal, Maria Laura Gennaro, Richard Pine   +7 more
doaj   +1 more source

Proteomic Profiling of Alveolar Macrophages Identifies Loss of Lysosomal Content as an Indicator of Nanofiber‐Induced Frustrated Phagocytosis

Small, EarlyView.
This proteomic study examines how nanofibers affect lung macrophages by analyzing protein changes following exposure to various fibrous materials. Nanofibers triggered the release of inflammatory enzymes, and importantly, lysosomal content release was identified as an early event associated with frustrated phagocytosis. Seventeen sensitive and relevant
Tobias Stobernack, Antje Vennemann, Carla Ribalta, Julia Schendel, Oliver Gräb, Rico Ledwith, Mario Pink, Andrea Haase, Martin Wiemann, Verónica I. Dumit   +9 more
wiley   +1 more source

Prevalence and risk factors of latent tuberculosis infection among health care workers in Malaysia

BMC Infectious Diseases, 2011
Background Health care workers are exposed to patients with tuberculosis and are at risk of nosocomial infection. The aim of this study was to determine the prevalence and factors associated with latent tuberculosis infection among health care workers in
Rampal Krishna, Rafiza Shaharudin, Tahir Aris   +2 more
doaj   +1 more source

Association between diabetes mellitus and tuberculosis in United States-born and foreign-born populations in San Francisco. [PDF]

PLoS ONE, 2014
The impact of diabetes on tuberculosis in United States and foreign-born populations in San Francisco has not been studied.To determine the characteristics, prevalence and temporal trends of diabetes in US and foreign-born persons attending the San ...
Gompol Suwanpimolkul, Jennifer A Grinsdale, Leah G Jarlsberg, Julie Higashi, Dennis H Osmond, Philip C Hopewell, Midori Kato-Maeda   +6 more
doaj   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

The Prevalence of Latent Tuberculosis Infection and Smear Positive Pulmonary Tuberculosis in People with Household Close Contact with Tuberculosis in North of Iran

Iranian Journal of Medical Sciences, 2015
One of the recommended strategies for preventing tuberculosis is to screen high-risk populations with respect to Mycobacterium tuberculosis (TB) infection. The aim of the present study was to investigate latent infection and active tuberculosis in people
Mahmood Moosazadeh, Narges Khanjani, Mohammadreza Parsaee   +2 more
doaj  

Incidence and risk factors for tuberculosis in people living with HIV: cohort from HIV referral health centers in Recife, Brazil. [PDF]

PLoS ONE, 2013
OBJECTIVE: To identify the incidence of and risk factors for tuberculosis in people living with HIV (PLHIV). DESIGN: Observational, prospective cohort study. METHODS: A total of 2069 HIV-infected patients was observed between July 2007 and December 2010.
Joanna d'Arc Lyra Batista, Maria de Fátima Pessoa Militão de Albuquerque, Magda Maruza, Ricardo Arraes de Alencar Ximenes, Marcela Lopes Santos, Ulisses Ramos Montarroyos, Demócrito de Barros Miranda-Filho, Heloisa Ramos Lacerda, Laura Cunha Rodrigues   +8 more
doaj   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source