Results 11 to 20 of about 2,892 (211)

Studies in hypertriglyceridaemia VI: serum lathosterol concentration is raised in hypertriglyceridaemic non‐diabetic males with hyperinsulinaemia [PDF]

Journal of Internal Medicine, 1999
Abstract.Objectives. To assess the cholesterol synthesis rate in primary hypertriglyceridaemia using the serum unesterified lathosterol concentration as an indicator.Design. A cross‐sectional, case–control study.Setting. The Karolinska Hospital, Stockholm.Subjects. Randomly selected hyper‐ (n = 53) and normotriglyceridaemic (n = 57) males, 40–50 years,
Ingemar Björkhem
exaly   +3 more sources

Prognostic significance of serum cholesterol, lathosterol, and sitosterol in old age; a 17-year population study

Annals of Medicine, 2011
BACKGROUND. Low serum total cholesterol is frequently associated with worse survival in older people, but mechanisms of this association are poorly understood. AIMS. Characteristics of cholesterol metabolism were related to survival in a random 75 + population sample. METHODS.
Timo E Strandberg
exaly   +3 more sources

Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency [PDF]

Human Molecular Genetics, 2003
Lathosterol 5-desaturase catalyzes the conversion of lathosterol to 7-dehydrocholesterol in the next to last step of cholesterol synthesis. Inborn errors of cholesterol synthesis underlie a group of human malformation syndromes including Smith-Lemli-Opitz syndrome, desmosterolosis, CHILD syndrome, CDPX2 and lathosterolosis. We disrupted the lathosterol
Christopher A Wassif, Lisa Kratz, Martina Kovarova   +2 more
exaly   +3 more sources

Markers of cholesterol synthesis to cholesterol absorption across the spectrum of non‐dialysis CKD: An observational study

Pharmacology Research & Perspectives, 2021
In dialysis patients, cholesterol‐lowering therapy with statins is less effective than in other high‐risk patients. This may be explained by a shift from cholesterol synthesis toward cholesterol absorption. In line, markers of cholesterol absorption—such
Insa E. Emrich, Gunnar H. Heine, P. Christian Schulze, Kyrill S. Rogacev, Danilo Fliser, Stefan Wagenpfeil, Michael Böhm, Dieter Lütjohann, Oliver Weingärtner   +8 more
doaj   +1 more source

Presence of Cholesterol in Non-Animal Organisms: Identification and Quantification of Cholesterol in Crude Seed Oil from Perilla frutescens and Dehydrated Pyropia tenera

Molecules, 2021
Studies have reported that cholesterol, a molecule found mainly in animals, is also present in some plants and algae. This study aimed to determine whether cholesterol exists in three dehydrated algae species, namely, Pyropia tenera, Saccharina japonica,
Min-Ji Oh, Hee-Jin So, Eun-Sik Hong, Jung-Ah Shin, Ki-Teak Lee   +4 more
doaj   +1 more source

Plasma Cholesterol and Lathosterol Levels in Term Infants in the Early Neonatal Period [PDF]

Pediatric Research, 1992
Plasma cholesterol concentrations increase after birth. Whether this is due to increased cholesterol synthesis has not been reported. Additionally, it is not known if formulas, which lack cholesterol, result in higher rates of cholesterol synthesis than feeding breast milk.
J J, Hamilton, A, Synnes, S M, Innis
openaire   +2 more sources

Besnoitia besnoiti infection alters both endogenous cholesterol de novo synthesis and exogenous LDL uptake in host endothelial cells [PDF]

, 2008
Besnoitia besnoiti, an apicomplexan parasite of cattle being considered as emergent in Europe, replicates fast in host endothelial cells during acute infection and is in considerable need for energy, lipids and other building blocks for offspring ...
Silva, Liliana M. R., Lütjohann, Dieter, Hamid, Penny, Velasquez, Zahady D., Kerner, Katharina, Larrazabal, Camilo, Failing, Klaus, Hermosilla, Carlos, Taubert, Anja   +8 more
core   +2 more sources

Serum lathosterol levels in human subjects reflect changes in whole body cholesterol synthesis induced by lovastatin but not dietary cholesterol.

Journal of Lipid Research, 1995
We measured serum lathosterol levels and whole body cholesterol synthesis by sterol balance in 12 human subjects on a metabolic ward in four randomly allocated, 6-7 week periods: 1) lovastatin (40 mg b.i.d.) + low cholesterol diet (mean 246 mg/day); 2 ...
W C Duane
doaj   +1 more source

Plasma Levels of Lathosterol and Phytosterols in Relation to Age, Sex, Anthropometric Parameters, Plasma Lipids and Apolipoprotein E Phenotype in 160 Dutch Families [PDF]

, 1991
In this study, the relation of plasma levels of lathosterol (an indicator of whole body cholesterol synthesis) and plant sterols (indicator of cholesterol absorption) with age, sex, weight, height, plasma lipids, and lipoproteins, and with apolipoprotein
Alberts, Assmann, Bjorkhem, Endo, Friedewald, Frishman, Goodman, Gylling, Havekes, Havel, Kempen, Kesaniemi, Lopes-Virella, Miettinen, Miettinen, Miettinen, Miettinen, Nestel, Palmer, Sing, Smit, Stasse-Wolthuis, Tilvis, Utermann   +23 more
core   +1 more source

Age-associated alterations in cholesterol homeostasis: evidence from a cross-sectional study in a Northern Italy population. [PDF]

, 2014
BACKGROUND: The modifications of cholesterol metabolism associated with aging are ill-defined. The objective of this study was to define age-associated alterations of the different metabolic pathways controlling cholesterol homeostasis by analyzing ...
Anzivino C, BALDELLI, Enrica, BERTOLOTTI, Marco, Carulli N., CARULLI, Lucia, Del Puppo M, LORIA, Paola, Magni A, MUSSI, Chiara, OGNIBENE, Silvia, Pellegrini E   +10 more
core   +1 more source