Results 41 to 50 of about 2,892 (211)

Serum 27-hydroxycholesterol in patients with primary biliary cirrhosis suggests alteration of cholesterol catabolism to bile acids via the acidic pathway

Journal of Lipid Research, 1998
Reduced cholesterol synthesis has been reported in patients with primary biliary cirrhosis but no data are available on changes in cholesterol catabolism induced by the disease.
M. Del Puppo, M. Galli Kienle, M.L. Petroni, A. Crosignani, M. Podda   +4 more
doaj   +1 more source

Phylogenomic analysis of integral diiron membrane histidine motif-containing enzymes in ciliates provides insights into their function and evolutionary relationships [PDF]

, 2017
The Integral Membrane Histidine Motif-containing Enzymes (IMHME) are a class of binuclear non-heme iron proteins widely distributed among prokaryotes and eukaryotes.
Cid, Nicolás Gonzalo, Elguero, María Eugenia, Montes, María Guadalupe, Nudel, Berta Clara, Nusblat, Alejandro David, Sánchez Granel, María Luz   +5 more
core   +1 more source

Fecal neutral steroids and bile acids from germfree rats

Journal of Lipid Research, 1969
The amount and composition of fecal neutral sterols and bile acids excreted by adult male germfree and conventional rats have been determined. The amounts of neutral sterols excreted were 12.8 (germfree) and 19.5 (conventional) mg/kg of body wt per day ...
Thomas F. Kellogg, Bernard S. Wostmann
doaj   +1 more source

Metabolomics approach reveals effects of antihypertensives and lipid-lowering drugs on the human metabolism [PDF]

, 2014
The mechanism of antihypertensive and lipid-lowering drugs on the human organism is still not fully understood. New insights on the drugs' action can be provided by a metabolomics-driven approach, which offers a detailed view of the physiological ...
Barbara Thorand, Christian Gieger, Christine Meisinger, Elisabeth Altmaier, Gabi Kastenmüller, Gisela Fobo, Jerzy Adamski, Karsten Suhre, Margit Heier, Melanie Waldenberger, Thomas Illig, Werner Römisch-Margl   +11 more
core   +2 more sources

Phytosterol plasma concentrations and coronary heart disease in the prospective Spanish EPIC cohort

Journal of Lipid Research, 2010
Phytosterol intake with natural foods, a measure of healthy dietary choices, increases plasma levels, but increased plasma phytosterols are believed to be a coronary heart disease (CHD) risk factor.
Verónica Escurriol, Montserrat Cofán, Concepción Moreno-Iribas, Nerea Larrañaga, Carmen Martínez, Carmen Navarro, Laudina Rodríguez, Carlos A. González, Dolores Corella, Emilio Ros   +9 more
doaj   +1 more source

Low density lipoprotein cholesterol is inversely correlated with abdominal visceral fat area: a magnetic resonance imaging study [PDF]

, 2011
Background Visceral Fat Area (VFA) is an independent predictor of coronary disease. While low density lipoprotein cholesterol (LDL-C) is used to determine risk and guide therapy, its accuracy fails in obese patients who may have low LDL-C despite high ...
Michel R Hoenig, Gary Cowin, Raymond Buckley, Christine McHenery, Alan Coulthard   +4 more
core   +1 more source

Impact of simvastatin, niacin, and/or antioxidants on cholesterol metabolism in CAD patients with low HDL

Journal of Lipid Research, 2003
The HDL Atherosclerosis Treatment Study (HATS) demonstrated a clinical benefit in coronary artery disease patients with low HDL cholesterol (HDL-C) levels treated with simvastatin and niacin (S-N) or S-N plus antioxidants (S-N+A) compared with ...
Nirupa R. Matthan, Ann Giovanni, Ernst J. Schaefer, B.Greg Brown, Alice H. Lichtenstein   +4 more
doaj   +1 more source

Relationship between Diabetes Mellitus and Serum Lathosterol and Campesterol Levels: The CACHE Study DM Analysis

Journal of Atherosclerosis and Thrombosis, 2023
Risk of cardiovascular disease is increased in patients with diabetes mellitus (DM). Cholesterol metabolism (hepatic synthesis and intestinal absorption) is known to be associated with cardiovascular risk. Next, we examined the association of DM with cholesterol absorption/synthesis.The CACHE Consortium, which is comprised of 13 research groups in ...
Matsumura, Takeshi, Ishigaki, Yasushi, Nakagami, Tomoko, Akiyama, Yusuke, Ishibashi, Yutaka, Ishida, Tatsuro, Fujii, Hisako, Harada-Shiba, Mariko, Kabata, Daijiro, Kihara, Yasuki, Kotani, Kazuhiko, Kurisu, Satoshi, Masuda, Daisaku, Matoba, Tetsuya, Matsuki, Kota, Mori, Kenta, Nakazato, Masamitsu, Taniuchi, Satsuki, Ueno, Hiroaki, Yamashita, Shizuya, Yoshida, Hiroshi, Yoshida, Hisako, Shoji, Tetsuo   +22 more
openaire   +2 more sources

High cholesterol absorption efficiency enhances proatherogenic properties of low‐density lipoprotein particles

Journal of Internal Medicine, Volume 299, Issue 6, Page 711-725, June 2026.
Abstract Background and Aims High cholesterol absorption efficiency is determined by genetic variation in small intestinal sterol transporters and affects one‐third of individuals. Their risk for atherosclerotic cardiovascular disease (ASCVD) is increased compared with low cholesterol absorbers, despite similar serum lipid concentrations.
Katariina Öörni, Lauri Äikäs, Maija Ruuth, Feven Tigistu‐Sahle, Reijo Käkelä, Ingmar Wester, Helena Gylling, Piia Simonen   +7 more
wiley   +1 more source

Sterols in the small intestine of the rat, guinea pig, and rabbit

Journal of Lipid Research, 1971
The sterol content and composition of the small intestinal mucosa has been studied in the rat, guinea pig, and rabbit. In the three species, noncholesterol sterols formed a large proportion of the total sterol content. In the rat, the contribution due to
NEIL McINTYRE, KATHARINA KIRSCH, J.C. ORR, K.J. ISSELBACHER   +3 more
doaj   +1 more source