Results 21 to 30 of about 1,616 (166)

Sialic acid content of low density lipoprotein and its relation to lipid concentrations and metabolism of low density lipoprotein and cholesterol

Journal of Lipid Research, 2000
A low sialic acid content in low density lipoprotein (LDL) has been associated with atherogenicity and coronary artery disease (CAD) in many but not all studies. We investigated associations of the sialic acid-to-apolipoprotein B (apoB) ratio of LDL with
Nina Lindbohm, Helena Gylling, Tatu A. Miettinen   +2 more
doaj   +1 more source

Long-term effects of sterol depletion in C. elegans

Journal of Lipid Research, 2004
Three major long-term effects of sterol deprivation in Caenorhabditis elegans are described. 1) The life expectancy of sterol-deprived wild-type animals is decreased by more than 40%. Similar decreases are found in animals carrying mutations in the daf-9,
Mark Merris, Jessica Kraeft, G.S. Tint, John Lenard   +3 more
doaj   +1 more source

Cholesterol absorption and synthesis markers in individuals with and without a CHD event during pravastatin therapy: insights from the PROSPER trial

Journal of Lipid Research, 2010
Cholesterol homeostasis, defined as the balance between absorption and synthesis, influences circulating cholesterol concentrations and subsequent coronary heart disease (CHD) risk.
Nirupa R. Matthan, Nancy Resteghini, Michele Robertson, Ian Ford, James Shepherd, Chris Packard, Brendan M. Buckley, J. Wouter Jukema, Alice H. Lichtenstein, Ernst J. Schaefer   +9 more
doaj   +1 more source

Genetic Analysis of Indicators of Cholesterol Synthesis and Absorption: Lathosterol and Phytosterols in Dutch Twins and Their Parents [PDF]

Twin Research, 2003
Significant familial aggregation was observed for plasma levels of lathosterol (an indicator of whole-body cholesterol synthesis) and plant sterols campesterol and beta-sitosterol (indicators of cholesterol absorption) in 160 Dutch families consisting of adolescent mono- and dizygotic twin pairs and their parents.
Boomsma, D.I., Princen, H.M., Frants, R.R., Leuven, J.A.G., Kempen, H.J.M.   +4 more
openaire   +4 more sources

Differential gene expression of Caenorhabditis elegans grown on unmethylated sterols or 4α-methylsterols

Journal of Lipid Research, 2007
Transcriptional profiles of Caenorhabditis elegans grown on unmethylated sterols (desMSs) or on 4α-methylsterols (4MSs) were compared using microarrays.
Merris Mark, Wang Tongsheng, Soteropoulos Patricia, Lenard John   +3 more
doaj   +1 more source

The Plasma Distribution of Non-cholesterol Sterol Precursors and Products of Cholesterol Synthesis and Phytosterols Depend on HDL Concentration

Frontiers in Nutrition, 2022
Non-cholesterol sterols are transported in plasma lipoproteins and are consequently important in cholesterol metabolism. We investigated the distribution of non-cholesterol sterol precursors of cholesterol synthesis (NCSPCS), oxysterols, and phytosterols
Valéria Sutti Nunes, Eliton Juniro da Silva, Guilherme da Silva Ferreira, Sayonara Ivana Santos de Assis, Patrícia Miralda Cazita, Edna Regina Nakandakare, Vanessa Helena de Souza Zago, Eliana Cotta de Faria, Eder Carlos Rocha Quintão   +8 more
doaj   +1 more source

Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity

Journal of Lipid Research, 2004
The roles of polymorphisms of the sitosterolemia genes ABCG5 and ABCG8 in the regulation of cholesterol metabolism and insulin sensitivity were studied in mildly hypercholesterolemic noncoronary subjects (n = 263, 144 men and 119 women) divided into ...
Helena Gylling, Maarit Hallikainen, Jussi Pihlajamäki, Jyrki Ågren, Markku Laakso, Radhakrishnan A. Rajaratnam, Rainer Rauramaa, Tatu A. Miettinen   +7 more
doaj   +1 more source

Endogenous cholesterol synthesis is associated with VLDL-2 apoB-100 production in healthy humans

Journal of Lipid Research, 2003
Subjects with high plasma cholesterol levels exhibit a high production of VLDL apolipoprotein B-100 (apoB-100), suggesting that cholesterol is a mediator for VLDL production.
Berthil H.C.M.T. Prinsen, Johannes A. Romijn, Peter H. Bisschop, Martina M.J. de Barse, P.Hugh R. Barrett, Marie¨tte Ackermans, Ruud Berger, Ton J. Rabelink, Monique G.M. de Sain-van der Velden   +8 more
doaj   +1 more source

Severe Genotype, Pancreatic Insufficiency and Low Dose of Pancreatic Enzymes Associate with Abnormal Serum Sterol Profile in Cystic Fibrosis

Biomolecules, 2021
Background: Several factors could lead to lipid disturbances observed in cystic fibrosis (CF). This study aimed to assess sterol homeostasis in CF and define potential exogenous and endogenous determinants of lipid dysregulation.
Sławomira Drzymała-Czyż, Patrycja Krzyżanowska-Jankowska, Krzysztof Dziedzic, Aleksandra Lisowska, Szymon Kurek, Joanna Goździk-Spychalska, Victoria Kononets, Dagmara Woźniak, Edyta Mądry, Jarosław Walkowiak   +9 more
doaj   +1 more source

Biosynthesis of squalene and sterols by rat aorta

Journal of Lipid Research, 1971
The synthesis of nonsaponifiable compounds from radioactive mevalonate by segments of adult rat aorta was studied in vitro. The labeled products consisted largely of substances with the chromatographic and chemical behavior of squalene, lanosterol ...
MARIE M. DALY
doaj   +1 more source