Results 111 to 120 of about 125,401 (357)
Journal of Materials Research and Technology, 2021 Limestone calcined clay cement (LC3) is a new type of low-carbon cement that can reduce energy consumption and carbon dioxide emissions while meeting the performance requirements of ordinary cement.
Jun Liu +5 more
semanticscholar +1 more source
Glutamate induces autophagy via the two-pore channels in neural cells [PDF]
, 2016 NAADP (nicotinic acid adenine dinucleotide phosphate) has been proposed as a second messenger for glutamate in neuronal and glial cells via the activation of the lysosomal Ca2+ channels TPC1 and TPC2.
+11 more
core +4 more sources
Autophagy-independent LC3 function in vesicular traffic [PDF]
Autophagy, 2010 As protein folding is an imperfect process, the endoplasmic reticulum (ER) contains folding as well as ER-associated degradation (ERAD) machineries. In order to prevent premature interruption of folding, ERAD regulators and effectors such as EDEM1 and OS-9 are selectively cleared from the ER in so-called EDEMosomes to downregulate the degradative ...
de Haan Cornelis A M +2 more
openaire +3 more sources
Advanced Science, EarlyView.This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia +5 more
wiley +1 more source
Civil and Environmental EngineeringSupplementary cementitious materials (SCMs) has become an important alternative for engineers to mitigate the carbon footprint caused by cement production, by a full or a partial replacement of cement with eco-friendly binders to be used in construction ...
Husain Muhammed A. +1 more
doaj +1 more source
Nucleocytoplasmic distribution and dynamics of the autophagosome marker EGFP-LC3. [PDF]
PLoS ONE, 2010 The process of autophagy involves the formation of autophagosomes, double-membrane structures that encapsulate cytosol. Microtubule-associated protein light chain 3 (LC3) was the first protein shown to specifically label autophagosomal membranes in ...
Kimberly R Drake +2 more
doaj +1 more source
Autophagy in Microglia and Alzheimer's disease [PDF]
, 2019 Alzheimer’s disease (AD) is the most common neurodegenerative disease, characterized by amyloid-beta plaques, neurofibrillary tangles and neuroinflammation. Autophagy has been associated with several neurodegenerative diseases.
Houtman, Judith
core +1 more source
Halofuginone is a Molecular Glue Degrader of Integrin β4
Advanced Science, EarlyView.Integrin β4 overexpression is linked to aggressive tumors and poor prognosis, but targeted therapies are lacking. We identified halofuginone (HF) as a molecular glue degrader that promotes integrin β4 degradation via the CRL4BWDR18 E3 ligase. HF suppresses tumor progression in vitro and in vivo, offering a new strategy for targeting oncogenic ...
Wei Gong +8 more
wiley +1 more source
Crystal structure of 25,27-dibenzyloxy-26-benzoyloxy-28-hydroxycalix[ 4]arene, C49H40O5
Zeitschrift für Kristallographie - New Crystal Structures, 2006 C49H40O5, triclinic, P1̅ (no. 2), a = 10.8865(2) Å, b = 18.2743(3) Å, c = 18.3545(3) Å, α = 85.166(1)°, β = 86.233(1)°, γ = 84.268(1)°, V = 3614.3 Å3, Z = 4, Rgt(F) = 0.054, wRref(F2) = 0.148, T = 120 K.
Kuhn P., Matt D., Toupet L., Louati A.
doaj +1 more source
Advanced Science, EarlyView.Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang +8 more
wiley +1 more source