APOE4-Expressing Astrocytes Exhibit Parkinson's Disease-Related Pathology. [PDF]
Lior N +5 more
europepmc +1 more source
Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response
Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril +2 more
wiley +1 more source
Magnetic fields as biophysical activators of autophagy: A preclinical systematic review. [PDF]
Emanuele E +6 more
europepmc +1 more source
Inflammation‐Regeneration Axis of Dental Pulp Stem Cells: Wnt/NF‐κB Crosstalk
ABSTRACT Background Inflammation critically determines dental pulp regenerative outcomes, with dental pulp stem cells (DPSCs) orchestrating tissue homeostasis through differentiation, self‐renewal and immunomodulation processes dynamically regulated by Wnt/β‐catenin and NF‐κB signaling crosstalk.
V. Rajasekar +4 more
wiley +1 more source
The Role of Oxidative Stress in Periodontitis
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
wiley +1 more source
Differential regulation of p62-ubiquitin conjugates in neurons versus astrocytes during cellular stress. [PDF]
Sidibe DK +4 more
europepmc +1 more source
Bone biology in aging periodontal and peri‐implant tissues
Abstract Background Periodontal disease is an age‐related chronic inflammatory condition leading to tooth loss. Dental implants are an option for replacement of lost teeth in older adults. However, age‐related changes to alveolar bone may have pathological implications for its role in supporting the dentition and dental implants.
Dalia Rasheed Issa +2 more
wiley +1 more source
Cross-linked (R)-(+)-lipoic acid nanoparticles loaded with silibinin induce apoptosis and autophagy in glioblastoma cells. [PDF]
Dai X, Liu L, Guo N, Mao C, Yan X.
europepmc +1 more source
Muscle wasting in cancer cachexia: Mechanisms and the role of exercise
Abstract Cancer cachexia (CC) is a multifactorial disease marked by a severe and progressive loss of lean muscle mass and characterized further by inflammation and a negative energy/protein balance, ultimately leading to muscle atrophy and loss of muscle tissue.
Zoe P. Libramento +2 more
wiley +1 more source
SQSTM1/p62 UFMylation Enhances Autophagic Clearance of Pathogenic Mutant Huntingtin. [PDF]
Wang X +11 more
europepmc +1 more source

