Results 181 to 190 of about 63,437 (218)

Avian pathogenic Escherichia coli virulence protein Hcp2a induces incomplete autophagy in chicken HD11 cells. [PDF]

Poult Sci
Tian Y, Zhang Y, Lu L, Wang S, Dai L, Wang H, Nawaz S, Sun J, Shao Y, Wang Z, Tu J, Song X.   +11 more
europepmc   +1 more source

Dual‐Targeting Cuproptosis and Mitophagy via a Flavopiridol‐Copper Nanoplatform Potentiates Immunotherapy Against Uveal Melanoma

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren, Zhihong Deng, Sheng Lu, Jing Zhang, Wenbin Liu, Jia Tan   +5 more
wiley   +1 more source

Estrogen Regulates Microtubule-Associated Protein 1 Light Chain 3 in Mouse Uterine Endometrial Epithelium. [PDF]

Dev Reprod
Moon S, Lee S, Choi Y.
europepmc   +1 more source

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

Advanced Science, Volume 13, Issue 36, 29 June 2026.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou, Qiming Zhai, Zhihao Yao, Qing Li, Yan Yang, Si Wang, Chao Huang, Liangjing Xin, Tao Chen, Jinlin Song   +9 more
wiley   +1 more source

Caffeic Acid Counteracts LPS-Induced Inflammatory Damage in Yak Mammary Epithelial Cells Associated with NF-κB-Mediated Autophagy Regulation. [PDF]

Animals (Basel)
Li Y, Li X, Chen Z, Cen Y, Zhang C, Wang Y, Zeng R, Zhang D, Wang X, Li J, Xiong X.   +10 more
europepmc   +1 more source

Bacterial Pigments as Potential Antitumor Agents Against Gastrointestinal Cancers: A Comprehensive Systematic Review

Biotechnology and Applied Biochemistry, Volume 73, Issue 3, Page 1626-1646, June 2026.
ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara, Ricardo F. S. Pereira, Carla C. C. R. de Carvalho, Jose Prados, Consolación Melguizo, Raul Ortiz   +5 more
wiley   +1 more source

Quantitative analysis of autophagic flux reveals radiation-induced activation of SQSTM1-mediated degradation of protein aggregates and ER-phagy. [PDF]

J Radiat Res
Moriwaki T, Masuda T.
europepmc   +1 more source

USP5‐C‐MAF Axis Regulates Autophagy‐Dependent Neuronal Ferroptosis in Spinal Cord Injury Therapeutics

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
SCI induces significant upregulation of USP5 in neurons. The overexpressed USP5 stabilizes c‐MAF protein expression through its deubiquitinase activity, activating autophagy and accelerating the degradation of autophagic ferritin, thereby mediating neuronal ferroptosis. This ultimately leads to impaired functional recovery in SCI mice.
Shiyang Weng, Kai Wu, Yinjun Huang, Lei Cao, Huichao Fu   +4 more
wiley   +1 more source

Berbamine sensitizes hepatocellular carcinoma to chemotherapy by inhibiting autophagy <i>via</i> modulating SIRT1-mediated acetylation. [PDF]

Front Pharmacol
Peng Q, Xiao L, Huang X, Huang Z, Zhang G, Zhou J, Tan Y.   +6 more
europepmc   +1 more source