Molecular Mechanism of LC3 Lipidation and the Role of LC3 in Autophagosome Biogenesis
Molecular Mechanism of LC3 Lipidation and the Role of LC3 in Autophagosome Biogenesis総研大甲第1165号
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Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review
Photochemistry and Photobiology, EarlyView.Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima +6 more
wiley +1 more source
Regulatory mechanism of O-linked N-acetylglucosamine protein modification on autophagy in cancer. [PDF]
Clin Transl MedLi Y +5 more
europepmc +1 more source
Muscle wasting in cancer cachexia: Mechanisms and the role of exercise
Experimental Physiology, EarlyView.Abstract Cancer cachexia (CC) is a multifactorial disease marked by a severe and progressive loss of lean muscle mass and characterized further by inflammation and a negative energy/protein balance, ultimately leading to muscle atrophy and loss of muscle tissue.
Zoe P. Libramento +2 more
wiley +1 more source
Recent Update Targeting Autophagy-Apoptosis Crosstalk Using Bioactive Natural Products for Ovarian Cancer Treatment. [PDF]
BiomedicinesHarrath AH +3 more
europepmc +1 more source
One day of environment‐induced heat stress causes injury to the murine kidney
Experimental Physiology, EarlyView.Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths +3 more
wiley +1 more source
Autophagy cargo profiles in skeletal muscle during starvation and exercise. [PDF]
Autophagy RepFarhan M +10 more
europepmc +1 more source
Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse
Experimental Physiology, EarlyView.Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley +1 more source
Dexmedetomidine Suppresses Mitochondrial Autophagy and Apoptosis While Promoting Proliferation in Breast Cancer Cells in vitro via PI3K/AKT Signaling. [PDF]
Breast Cancer (Dove Med Press)Gu M +6 more
europepmc +1 more source
Cell Toxicity and Autophagy in A549 Cells Treated With Surface‐Functionalized Graphene Derivatives
Journal of Applied Toxicology, Volume 46, Issue 3, Page 821-832, March 2026.ABSTRACT Graphene oxide and its derivatives have unique physical and chemical properties with applications in many different fields. However, their biological effects and mechanisms of intracellular toxicity have not been completely clarified. In this study, we investigated the cytotoxic and autophagic activities of graphene oxide and its derivatives ...
Tae Yun Park +6 more
wiley +1 more source